SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ozi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 4ozi T-CELL RECEPTOR, S2,
BETA CHAIN
(Homo
sapiens) 		3 / 3 SER F  99
GLU F 126
ASP F 196
 None
 0.85A 2avdB-4oziF:
undetectable		 2avdB-4oziF:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 4ozi T-CELL RECEPTOR, S2,
BETA CHAIN
(Homo
sapiens) 		5 / 12 GLY F 107
GLY F 110
VAL F 108
THR F 113
VAL F   4
 None
 1.21A 4f84A-4oziF:
undetectable		 4f84A-4oziF:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4ozi T-CELL RECEPTOR, S2,
BETA CHAIN
(Homo
sapiens) 		5 / 12 ILE F  78
THR F  88
THR F 120
SER F   5
VAL F   4
 None
 1.20A 6bzoC-4oziF:
undetectable		 6bzoC-4oziF:
12.02