SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ozq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 12 THR A 491
GLY A 482
ALA A 480
ILE A 710
PHE A 436
 None
 1.50A 1vq1A-4ozqA:
undetectable		 1vq1A-4ozqA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 10 LEU A-178
LEU A-175
ILE A-209
GLU A-217
LEU A-219
 None
 0.99A 1wopA-4ozqA:
undetectable		 1wopA-4ozqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 11 ALA A -67
ILE A-262
VAL A-273
LEU A-294
ILE A-291
 None
 1.22A 2h42A-4ozqA:
undetectable		 2h42A-4ozqA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 12 VAL A 416
ILE A 423
VAL A 425
LEU A 727
THR A 726
 None
 1.07A 3fw3B-4ozqA:
undetectable		 3fw3B-4ozqA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		4 / 6 PRO A-244
LEU A-223
ALA A-147
PRO A-245
 None
 1.33A 3gv1A-4ozqA:
undetectable
3gv1C-4ozqA:
undetectable		 3gv1A-4ozqA:
11.89
3gv1C-4ozqA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		4 / 6 LEU A-223
ALA A-147
PRO A-245
PRO A-244
 None
 1.31A 3gv1A-4ozqA:
undetectable
3gv1B-4ozqA:
undetectable		 3gv1A-4ozqA:
11.89
3gv1B-4ozqA:
11.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		4 / 7 GLU A-217
TYR A-215
MET A -40
TRP A -30
 None
 0.84A 3jyrA-4ozqA:
49.8		 3jyrA-4ozqA:
52.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		3 / 3 ASN A-220
ASN A-143
GLU A-156
 None
 0.94A 3kpdC-4ozqA:
undetectable		 3kpdC-4ozqA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 10 ILE A 580
PHE A 471
ALA A 464
LEU A 467
ALA A 470
 None
 1.11A 3lw5B-4ozqA:
1.3		 3lw5B-4ozqA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 12 VAL A-174
LEU A-210
GLY A-183
ALA A-182
LEU A  -9
 None
 0.99A 3n8yB-4ozqA:
undetectable		 3n8yB-4ozqA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 9 ILE A-238
LEU A-172
LYS A-114
ILE A-144
GLY A-179
 None
 1.26A 3sj4X-4ozqA:
undetectable		 3sj4X-4ozqA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 12 GLN A 678
GLY A 702
GLU A 390
ALA A   0
ASN A  -3
 None
 1.33A 3t7sA-4ozqA:
undetectable		 3t7sA-4ozqA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 12 GLN A 678
GLY A 702
GLU A 390
ALA A   0
ASN A  -3
 None
 1.35A 3t7sC-4ozqA:
undetectable		 3t7sC-4ozqA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		6 / 11 GLY A -70
ALA A -69
VAL A-111
GLY A-110
THR A-277
PRO A-263
 None
 1.30A 3ufnA-4ozqA:
undetectable		 3ufnA-4ozqA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 12 THR A  -4
ALA A  -2
ALA A  -6
TRP A-212
TYR A-203
 None
 1.47A 4u15B-4ozqA:
undetectable		 4u15B-4ozqA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		4 / 5 GLU A 410
ALA A 412
GLU A 407
ASN A 719
 None
 1.45A 5dwkC-4ozqA:
undetectable		 5dwkC-4ozqA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		4 / 8 VAL A -27
GLY A-179
LEU A-175
THR A-177
 None
 1.03A 5sxqB-4ozqA:
undetectable		 5sxqB-4ozqA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		4 / 8 VAL A -27
GLY A-179
LEU A-175
THR A-177
 None
 1.00A 5syjA-4ozqA:
undetectable		 5syjA-4ozqA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 12 SER A 700
PHE A 479
LEU A 665
LEU A 639
VAL A 637
 None
 1.02A 5tudA-4ozqA:
undetectable		 5tudA-4ozqA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		6 / 12 ALA A -28
ALA A -32
GLY A-204
ALA A-182
PHE A-201
VAL A-189
 None
 1.45A 5w4zA-4ozqA:
undetectable		 5w4zA-4ozqA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		6 / 12 ALA A -28
ALA A -32
GLY A-204
ALA A-182
PHE A-201
VAL A-189
 None
 1.47A 5w4zB-4ozqA:
undetectable		 5w4zB-4ozqA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		5 / 11 PRO A-237
GLU A-240
PRO A-116
ALA A-207
PRO A-211
 None
 1.36A 6bm5A-4ozqA:
undetectable		 6bm5A-4ozqA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		4 / 7 ASP A -12
ALA A  -8
LYS A-181
LEU A-178
 None
 1.07A 6ci6A-4ozqA:
undetectable		 6ci6A-4ozqA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4ozq CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND KINESIN FAMILY
MEMBER 14 PROTEIN
(Escherichia
coli;
Mus
musculus) 		4 / 6 GLY A 641
SER A 605
ARG A 604
ARG A 591
 None
 1.11A 6dwdA-4ozqA:
undetectable
6dwdC-4ozqA:
undetectable		 6dwdA-4ozqA:
21.44
6dwdC-4ozqA:
21.44