SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ozr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4ozr ECDYSONE RECEPTOR
(Pediculus
humanus) 		4 / 7 VAL E 343
VAL E 371
CYH E 498
ARG E 357
 None
 1.17A 1t46A-4ozrE:
undetectable		 1t46A-4ozrE:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4ozr ECDYSONE RECEPTOR
(Pediculus
humanus) 		5 / 10 LEU E 364
ALA E 346
LEU E 349
ASP E 359
LEU E 355
 None
 1.07A 1yi4A-4ozrE:
undetectable		 1yi4A-4ozrE:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 4ozr ECDYSONE RECEPTOR
(Pediculus
humanus) 		3 / 3 LEU E 413
MET E 373
TYR E 420
 None
 0.67A 4p6xG-4ozrE:
18.4		 4p6xG-4ozrE:
24.91