SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ozs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 4ozs ALPHA SOLENOID
PROTEIN
(synthetic
construct) 		4 / 5 LEU A 152
GLY A 151
PHE A 130
ASN A 146
 None
 1.24A 3uq6B-4ozsA:
undetectable		 3uq6B-4ozsA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4ozs ALPHA SOLENOID
PROTEIN
(synthetic
construct) 		5 / 12 THR A  42
GLY A  46
LEU A  12
LEU A  18
ALA A  21
 None
 1.04A 5l0zA-4ozsA:
undetectable		 5l0zA-4ozsA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4ozs ALPHA SOLENOID
PROTEIN
(synthetic
construct) 		5 / 12 THR A 112
GLY A 116
LEU A  82
LEU A  88
ALA A  91
 None
 1.04A 5l0zA-4ozsA:
undetectable		 5l0zA-4ozsA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 4ozs ALPHA SOLENOID
PROTEIN
(synthetic
construct) 		4 / 6 PHE A  60
THR A  74
ASP A  80
GLY A  81
 None
 1.20A 5mraA-4ozsA:
undetectable
5mraB-4ozsA:
undetectable		 5mraA-4ozsA:
20.22
5mraB-4ozsA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 4ozs ALPHA SOLENOID
PROTEIN
(synthetic
construct) 		4 / 6 PHE A  95
THR A 109
ASP A 115
GLY A 116
 None
 1.26A 5mraA-4ozsA:
undetectable
5mraB-4ozsA:
undetectable		 5mraA-4ozsA:
20.22
5mraB-4ozsA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4ozs ALPHA SOLENOID
PROTEIN
(synthetic
construct) 		3 / 3 LYS A  69
PRO A  70
LYS A 101
 None
 0.96A 5y9yA-4ozsA:
undetectable		 5y9yA-4ozsA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4ozs ALPHA SOLENOID
PROTEIN
(synthetic
construct) 		3 / 3 LYS A 104
PRO A 105
LYS A 136
 None
 0.80A 5y9yA-4ozsA:
undetectable		 5y9yA-4ozsA:
20.79