SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ozu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 7 ARG A 200
ASN A 137
ASP A 183
LYS A 181
 None
 1.30A 1hwiC-4ozuA:
undetectable		 1hwiC-4ozuA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 7 ARG A 200
ASN A 137
ASP A 183
LYS A 181
 None
 1.31A 1hwiD-4ozuA:
undetectable		 1hwiD-4ozuA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 4ozu CORONIN
(Toxoplasma
gondii) 		3 / 3 CYH A 210
CYH A 217
HIS A 211
 None
None
TRS  A 401 (-3.8A)
 0.84A 2iwkA-4ozuA:
20.6		 2iwkA-4ozuA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 8 PHE A 164
LEU A 184
ALA A 145
ALA A 165
 None
 0.75A 2vcvP-4ozuA:
undetectable		 2vcvP-4ozuA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 5 VAL A 390
TYR A 362
VAL A 323
ASP A 324
 None
 1.02A 2x45A-4ozuA:
undetectable		 2x45A-4ozuA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 5 VAL A 390
TYR A 362
VAL A 323
ASP A 324
 None
 1.02A 2x45C-4ozuA:
undetectable		 2x45C-4ozuA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1314_1
(CHOLINE-BINDING
PROTEIN F)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 5 ASP A  91
ARG A  90
TYR A  43
GLU A  42
 None
ACT  A 402 (-4.7A)
None
None
 1.28A 2x8oA-4ozuA:
undetectable		 2x8oA-4ozuA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 4ozu CORONIN
(Toxoplasma
gondii) 		3 / 3 CYH A 210
CYH A 217
HIS A 211
 None
None
TRS  A 401 (-3.8A)
 0.89A 3dtuB-4ozuA:
undetectable		 3dtuB-4ozuA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 4ozu CORONIN
(Toxoplasma
gondii) 		3 / 3 CYH A 210
CYH A 217
HIS A 211
 None
None
TRS  A 401 (-3.8A)
 0.86A 3dtuD-4ozuA:
undetectable		 3dtuD-4ozuA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4ozu CORONIN
(Toxoplasma
gondii) 		3 / 3 ARG A  90
THR A  95
THR A 115
 ACT  A 402 (-4.7A)
None
None
 0.68A 3k2hB-4ozuA:
undetectable		 3k2hB-4ozuA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 4 LEU A 269
GLY A 284
SER A 267
SER A 266
 None
 1.16A 5uunA-4ozuA:
undetectable		 5uunA-4ozuA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 4 LEU A 269
GLY A 284
SER A 267
SER A 266
 None
 1.07A 5uunB-4ozuA:
undetectable		 5uunB-4ozuA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 4ozu CORONIN
(Toxoplasma
gondii) 		5 / 12 ILE A 385
ASP A 183
GLY A 182
ASN A 137
ASP A 274
 None
 1.00A 5x66A-4ozuA:
undetectable
5x66B-4ozuA:
undetectable		 5x66A-4ozuA:
21.78
5x66B-4ozuA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 5 VAL A 341
PRO A  68
GLY A  65
TYR A  22
 None
 1.18A 5x80A-4ozuA:
undetectable
5x80B-4ozuA:
undetectable		 5x80A-4ozuA:
17.01
5x80B-4ozuA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 5 PRO A  68
GLY A  65
TYR A  22
VAL A 341
 None
 1.08A 5x80C-4ozuA:
undetectable
5x80D-4ozuA:
undetectable		 5x80C-4ozuA:
17.01
5x80D-4ozuA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 4ozu CORONIN
(Toxoplasma
gondii) 		5 / 11 GLU A  42
GLY A 113
ALA A  71
ALA A  69
PRO A  68
 None
 1.14A 5yk2A-4ozuA:
undetectable		 5yk2A-4ozuA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4ozu CORONIN
(Toxoplasma
gondii) 		4 / 5 GLN A 106
THR A  95
HIS A  76
LEU A 117
 None
 1.42A 6aphA-4ozuA:
undetectable		 6aphA-4ozuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 4ozu CORONIN
(Toxoplasma
gondii) 		3 / 3 ARG A 200
GLY A 380
GLU A 381
 None
 0.60A 6fgdA-4ozuA:
undetectable		 6fgdA-4ozuA:
23.48