SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p05'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 8 GLY A 218
GLY A  58
PHE A 570
SER A  61
 None
 0.74A 1d0vA-4p05A:
undetectable		 1d0vA-4p05A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 11 ILE A 503
ASN A 358
SER A 519
GLY A 518
GLY A 517
 None
4NS  A 601 (-3.6A)
None
None
None
 1.46A 1ho5A-4p05A:
undetectable		 1ho5A-4p05A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 11 LEU A 264
ASP A 300
VAL A 298
GLY A 246
VAL A 289
 None
 0.90A 1hxwB-4p05A:
undetectable		 1hxwB-4p05A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 11 LEU A 264
GLY A 267
ASP A 300
VAL A 298
VAL A 289
 None
 0.83A 1hxwB-4p05A:
undetectable		 1hxwB-4p05A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 6 PRO A 175
HIS A 138
ILE A 212
SER A 254
 None
 1.10A 1sbrA-4p05A:
undetectable
1sbrB-4p05A:
undetectable		 1sbrA-4p05A:
16.40
1sbrB-4p05A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 5 SER A 519
SER A 498
THR A 501
ASN A 436
 None
None
4NS  A 601 (-4.2A)
4NS  A 601 (-3.3A)
 1.40A 1yvpA-4p05A:
undetectable		 1yvpA-4p05A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		3 / 3 THR A 141
PRO A 175
TYR A 196
 None
 0.96A 2dxrA-4p05A:
undetectable		 2dxrA-4p05A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KI5_A_AC2A1_1
(PROTEIN (THYMIDINE
KINASE))		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 GLU A 253
ILE A 503
ILE A 504
ARG A 213
GLU A 505
 None
 1.31A 2ki5A-4p05A:
undetectable		 2ki5A-4p05A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		3 / 3 GLY A 198
ARG A 206
TYR A 107
 None
 0.65A 2opxA-4p05A:
undetectable		 2opxA-4p05A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 11 TYR A 433
PHE A 429
ASP A 430
TYR A 473
VAL A 485
 None
 1.41A 2vcdA-4p05A:
undetectable		 2vcdA-4p05A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 4 ARG A 469
GLY A 489
GLU A 487
SER A 519
 None
 1.42A 2xctS-4p05A:
undetectable
2xctU-4p05A:
undetectable		 2xctS-4p05A:
22.86
2xctU-4p05A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 8 ASN A 353
ILE A 500
SER A 373
THR A 434
 None
4NS  A 601 (-3.7A)
None
None
 0.93A 2yoeB-4p05A:
undetectable
2yoeC-4p05A:
undetectable		 2yoeB-4p05A:
21.23
2yoeC-4p05A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 GLY A 517
ASN A 436
ASP A 450
ARG A 455
TYR A 497
 None
4NS  A 601 (-3.3A)
None
None
None
 1.42A 3a27A-4p05A:
undetectable		 3a27A-4p05A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 LEU A 264
GLY A 267
ASP A 300
VAL A 298
VAL A 289
 None
 0.79A 3cywA-4p05A:
undetectable		 3cywA-4p05A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 6 ALA A 222
ILE A 212
HIS A 138
ASN A 136
 None
 1.16A 3nneG-4p05A:
undetectable		 3nneG-4p05A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 10 LEU A 264
GLY A 267
ASP A 300
VAL A 298
VAL A 289
 None
 0.97A 3oxwA-4p05A:
undetectable		 3oxwA-4p05A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 10 LEU A 264
GLY A 267
ASP A 300
VAL A 298
VAL A 289
 None
 0.98A 3oy4B-4p05A:
undetectable		 3oy4B-4p05A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		3 / 3 ARG A 283
ARG A 374
ILE A 282
 None
 0.89A 4b7qA-4p05A:
9.4		 4b7qA-4p05A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		3 / 3 ARG A 283
ARG A 374
ILE A 282
 None
 0.91A 4b7qC-4p05A:
8.6		 4b7qC-4p05A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 8 MET A 569
ILE A 179
ARG A 187
VAL A  43
 None
 1.29A 4f4dB-4p05A:
undetectable		 4f4dB-4p05A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		3 / 3 PRO A 393
TYR A 433
GLY A 377
 None
 0.73A 4g2zA-4p05A:
undetectable		 4g2zA-4p05A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ASP A 453
THR A 434
GLN A 333
ASP A 317
GLN A 459
 None
 1.46A 4njhA-4p05A:
undetectable		 4njhA-4p05A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ASP A 453
THR A 434
GLN A 333
ASP A 317
GLN A 459
 None
 1.46A 4njhB-4p05A:
undetectable		 4njhB-4p05A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJI_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ASP A 453
THR A 434
GLN A 333
ASP A 317
GLN A 459
 None
 1.43A 4njiA-4p05A:
undetectable		 4njiA-4p05A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJI_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ASP A 453
THR A 434
GLN A 333
ASP A 317
GLN A 459
 None
 1.43A 4njiB-4p05A:
undetectable		 4njiB-4p05A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJJ_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ASP A 453
THR A 434
GLN A 333
ASP A 317
GLN A 459
 None
 1.42A 4njjA-4p05A:
undetectable		 4njjA-4p05A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJJ_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ASP A 453
THR A 434
GLN A 333
ASP A 317
GLN A 459
 None
 1.45A 4njjB-4p05A:
0.0		 4njjB-4p05A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ASP A 453
THR A 434
GLN A 333
ASP A 317
GLN A 459
 None
 1.44A 4njkA-4p05A:
undetectable		 4njkA-4p05A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJK_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ASP A 453
THR A 434
GLN A 333
ASP A 317
GLN A 459
 None
 1.45A 4njkB-4p05A:
undetectable		 4njkB-4p05A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 LEU A 316
ALA A 392
ASN A 358
ASN A 436
GLY A 452
 None
None
4NS  A 601 (-3.6A)
4NS  A 601 (-3.3A)
None
 0.87A 4r3aB-4p05A:
undetectable		 4r3aB-4p05A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 7 TYR A 488
PHE A 449
ILE A 504
GLY A 517
 None
 0.91A 4ze3A-4p05A:
undetectable		 4ze3A-4p05A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 8 PHE A 231
PHE A 178
TRP A 188
TRP A 189
 None
 1.09A 5amkA-4p05A:
undetectable		 5amkA-4p05A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 8 TYR A 488
PHE A 449
ILE A 504
GLY A 517
 None
 0.91A 5esjA-4p05A:
undetectable		 5esjA-4p05A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 8 SER A 502
PHE A 516
GLY A 515
THR A 137
 None
 0.92A 5flcB-4p05A:
undetectable		 5flcB-4p05A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 8 SER A 502
PHE A 516
GLY A 515
THR A 137
 None
 0.91A 5flcF-4p05A:
undetectable		 5flcF-4p05A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 7 ASP A 146
ASP A 172
TYR A 196
GLY A 198
 None
 1.10A 5hwaA-4p05A:
undetectable		 5hwaA-4p05A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 9 LEU A 264
GLY A 267
ASP A 300
VAL A 298
VAL A 289
 None
 0.96A 5kr0B-4p05A:
undetectable		 5kr0B-4p05A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 6 ILE A 212
PHE A 516
HIS A 558
PHE A 195
 None
 1.03A 5vkqA-4p05A:
undetectable
5vkqB-4p05A:
undetectable		 5vkqA-4p05A:
15.99
5vkqB-4p05A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 6 ILE A 547
ILE A 212
PHE A 516
HIS A 558
 None
 1.04A 5vkqA-4p05A:
undetectable
5vkqB-4p05A:
undetectable		 5vkqA-4p05A:
15.99
5vkqB-4p05A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 6 ILE A 547
ILE A 212
PHE A 516
HIS A 558
 None
 1.03A 5vkqA-4p05A:
undetectable
5vkqD-4p05A:
undetectable		 5vkqA-4p05A:
15.99
5vkqD-4p05A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 6 PHE A 195
ILE A 212
PHE A 516
HIS A 558
 None
 1.04A 5vkqA-4p05A:
undetectable
5vkqD-4p05A:
undetectable		 5vkqA-4p05A:
15.99
5vkqD-4p05A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ALA A 222
PHE A 220
LEU A 209
VAL A 237
GLY A 235
 None
 1.24A 5x24A-4p05A:
undetectable		 5x24A-4p05A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		5 / 12 ILE A 173
THR A 139
THR A 529
VAL A 530
VAL A 135
 None
 1.30A 6bzoC-4p05A:
undetectable		 6bzoC-4p05A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST
(Escherichia
coli) 		4 / 7 ASP A 130
TYR A 133
GLU A 535
GLU A 542
 None
 1.27A 6mn5B-4p05A:
undetectable		 6mn5B-4p05A:
9.48