SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p0e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 6 LEU A  93
ASP A 131
LEU A 144
HIS A  88
 None
 0.81A 1errB-4p0eA:
undetectable		 1errB-4p0eA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 6 HIS A 101
LEU A  96
PHE A 126
VAL A 124
 None
 1.33A 1ibgH-4p0eA:
undetectable		 1ibgH-4p0eA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 7 LEU A  67
THR A 105
LEU A 109
VAL A 120
 None
 0.60A 1ictD-4p0eA:
undetectable		 1ictD-4p0eA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 8 LEU A  67
THR A 105
LEU A 109
VAL A 120
 None
 0.81A 1sn5C-4p0eA:
undetectable		 1sn5C-4p0eA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 7 LEU A  67
THR A 105
LEU A 109
VAL A 120
 None
 0.71A 1tyrB-4p0eA:
undetectable		 1tyrB-4p0eA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		5 / 12 LEU A  17
LEU A   4
LEU A 109
ALA A 108
ALA A   7
 None
 1.12A 2bxpA-4p0eA:
undetectable		 2bxpA-4p0eA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 5 LEU A  93
ASP A 131
LEU A 144
HIS A  88
 None
 0.78A 2jfaA-4p0eA:
undetectable		 2jfaA-4p0eA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 5 LEU A  93
ASP A 131
LEU A 144
HIS A  88
 None
 0.78A 2qxsA-4p0eA:
undetectable		 2qxsA-4p0eA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 5 LEU A  93
ASP A 131
LEU A 144
HIS A  88
 None
 0.79A 2qxsB-4p0eA:
undetectable		 2qxsB-4p0eA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		5 / 9 LEU A  16
LEU A 173
GLY A 172
THR A  71
VAL A 120
 None
 1.29A 4c9kB-4p0eA:
undetectable		 4c9kB-4p0eA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 4p0e MAF-LIKE PROTEIN
YHDE
(Escherichia
coli) 		4 / 8 LEU A  67
THR A 105
LEU A 109
VAL A 120
 None
 0.79A 4ik7B-4p0eA:
undetectable		 4ik7B-4p0eA:
22.16