SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4p0j INTERLEUKIN-36
RECEPTOR
ANTAGONIST/INTERLEUK
IN-36 GAMMA CHIMERA
PROTEIN
(Homo
sapiens) 		4 / 5 GLY A  63
GLY A  64
ASN A  84
GLU A  41
 None
 0.51A 4fglC-4p0jA:
undetectable		 4fglC-4p0jA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4p0j INTERLEUKIN-36
RECEPTOR
ANTAGONIST/INTERLEUK
IN-36 GAMMA CHIMERA
PROTEIN
(Homo
sapiens) 		4 / 6 GLY A  63
GLY A  64
ASN A  84
GLU A  41
 None
 0.63A 4fglD-4p0jA:
undetectable		 4fglD-4p0jA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4p0j INTERLEUKIN-36
RECEPTOR
ANTAGONIST/INTERLEUK
IN-36 GAMMA CHIMERA
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 133
LEU A 121
LEU A  78
GLU A  81
LEU A  68
 None
 1.11A 4wg0F-4p0jA:
undetectable
4wg0G-4p0jA:
undetectable
4wg0H-4p0jA:
undetectable		 4wg0F-4p0jA:
6.94
4wg0G-4p0jA:
6.94
4wg0H-4p0jA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4p0j INTERLEUKIN-36
RECEPTOR
ANTAGONIST/INTERLEUK
IN-36 GAMMA CHIMERA
PROTEIN
(Homo
sapiens) 		5 / 11 GLU A  81
LEU A  68
LEU A  78
LEU A 133
LEU A 121
 None
 1.14A 4wg0G-4p0jA:
undetectable
4wg0H-4p0jA:
undetectable
4wg0I-4p0jA:
undetectable		 4wg0G-4p0jA:
6.94
4wg0H-4p0jA:
6.94
4wg0I-4p0jA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4p0j INTERLEUKIN-36
RECEPTOR
ANTAGONIST/INTERLEUK
IN-36 GAMMA CHIMERA
PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  63
GLY A  64
ASN A  84
GLU A  41
ILE A  42
 None
 0.94A 4zvmA-4p0jA:
undetectable
4zvmB-4p0jA:
undetectable		 4zvmA-4p0jA:
21.66
4zvmB-4p0jA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4p0j INTERLEUKIN-36
RECEPTOR
ANTAGONIST/INTERLEUK
IN-36 GAMMA CHIMERA
PROTEIN
(Homo
sapiens) 		5 / 11 GLY A  63
GLY A  64
ASN A  84
GLU A  41
ILE A  42
 None
 1.05A 4zvmA-4p0jA:
undetectable
4zvmB-4p0jA:
undetectable		 4zvmA-4p0jA:
21.66
4zvmB-4p0jA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 4p0j INTERLEUKIN-36
RECEPTOR
ANTAGONIST/INTERLEUK
IN-36 GAMMA CHIMERA
PROTEIN
(Homo
sapiens) 		4 / 4 VAL A 131
LEU A  59
ASN A 142
ASP A  13
 None
 1.21A 5vcyA-4p0jA:
undetectable		 5vcyA-4p0jA:
18.93