SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4p15 BACILLUS LEHENSIS
CLPC N-TERMINAL
DOMAIN
(Bacillus
lehensis) 		5 / 12 GLY A  54
GLN A  51
GLN A  52
ILE A  45
GLN A 137
 None
None
None
SO4  A 202 (-4.5A)
None
 1.30A 2azxA-4p15A:
undetectable		 2azxA-4p15A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4p15 BACILLUS LEHENSIS
CLPC N-TERMINAL
DOMAIN
(Bacillus
lehensis) 		5 / 12 GLY A  54
GLN A  51
GLN A  52
ILE A  45
GLN A 137
 None
None
None
SO4  A 202 (-4.5A)
None
 1.28A 2azxB-4p15A:
undetectable		 2azxB-4p15A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4p15 BACILLUS LEHENSIS
CLPC N-TERMINAL
DOMAIN
(Bacillus
lehensis) 		5 / 8 GLY A  44
GLY A 104
ILE A 108
LEU A 110
GLU A 106
 SO4  A 202 (-3.2A)
SO4  A 202 (-3.4A)
None
None
SO4  A 202 (-2.9A)
 1.25A 4mwzB-4p15A:
undetectable		 4mwzB-4p15A:
21.46