SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_C_CCSC47_0 (GLUTATHIONE S-TRANSFERASE)	4p1b	TOLUENE-4-MONOOXYGEN ASE SYSTEM FERREDOXIN SUBUNIT (Pseudomonas mendocina)	4 / 6	THR H 75 LEU H 86 LYS H 39 TYR H 41	None	1.18A	1gtiC-4p1bH: undetectable	1gtiC-4p1bH: 20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHX_B_PXLB313_1 (PYRIDOXAL KINASE)	4p1b	TOLUENE-4-MONOOXYGEN ASE SYSTEM PROTEIN B (Pseudomonas mendocina)	4 / 8	VAL C 19 VAL C 80 PHE C 10 HIS C 37	None	0.74A	3fhxB-4p1bC: undetectable	3fhxB-4p1bC: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_A_SAMA201_0 (YAEB-LIKE PROTEIN RPA0152)	4p1b	TOLUENE-4-MONOOXYGEN ASE SYSTEM FERREDOXIN SUBUNIT (Pseudomonas mendocina)	5 / 12	LEU H 86 HIS H 36 TYR H 57 GLY H 60 LEU H 52	None	1.29A	3okxA-4p1bH: undetectable	3okxA-4p1bH: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_B_SAMB201_1 (YAEB-LIKE PROTEIN RPA0152)	4p1b	TOLUENE-4-MONOOXYGEN ASE SYSTEM FERREDOXIN SUBUNIT (Pseudomonas mendocina)	5 / 12	LEU H 86 HIS H 36 TYR H 57 GLY H 60 LEU H 52	None	1.27A	3okxB-4p1bH: undetectable	3okxB-4p1bH: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L7I_B_SAMB501_0 (S-ADENOSYLMETHIONINE SYNTHASE)	4p1b	TOLUENE-4-MONOOXYGEN ASE SYSTEM FERREDOXIN SUBUNIT (Pseudomonas mendocina)	4 / 8	ASP H 96 LEU H 9 ASN H 32 ILE H 98	None	1.07A	4l7iA-4p1bH: undetectable	4l7iA-4p1bH: 14.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTI_C_CCSC47_0","GLUTATHIONE S-TRANSFERASE","4p1b","TOLUENE-4-MONOOXYGENASE SYSTEM FERREDOXIN SUBUNIT","Pseudomonas mendocina",4,"THR H  75;LEU H  86;LYS H  39;TYR H  41","None","1.18A","1gtiC-4p1bH:undetectable","1gtiC-4p1bH:20.51"],["3FHX_B_PXLB313_1","PYRIDOXAL KINASE","4p1b","TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN B","Pseudomonas mendocina",4,"VAL C  19;VAL C  80;PHE C  10;HIS C  37","None","0.74A","3fhxB-4p1bC:undetectable","3fhxB-4p1bC:16.87"],["3OKX_A_SAMA201_0","YAEB-LIKE PROTEIN RPA0152","4p1b","TOLUENE-4-MONOOXYGENASE SYSTEM FERREDOXIN SUBUNIT","Pseudomonas mendocina",5,"LEU H  86;HIS H  36;TYR H  57;GLY H  60;LEU H  52","None","1.29A","3okxA-4p1bH:undetectable","3okxA-4p1bH:20.11"],["3OKX_B_SAMB201_1","YAEB-LIKE PROTEIN RPA0152","4p1b","TOLUENE-4-MONOOXYGENASE SYSTEM FERREDOXIN SUBUNIT","Pseudomonas mendocina",5,"LEU H  86;HIS H  36;TYR H  57;GLY H  60;LEU H  52","None","1.27A","3okxB-4p1bH:undetectable","3okxB-4p1bH:20.11"],["4L7I_B_SAMB501_0","S-ADENOSYLMETHIONINE SYNTHASE","4p1b","TOLUENE-4-MONOOXYGENASE SYSTEM FERREDOXIN SUBUNIT","Pseudomonas mendocina",4,"ASP H  96;LEU H   9;ASN H  32;ILE H  98","None","1.07A","4l7iA-4p1bH:undetectable","4l7iA-4p1bH:14.88"]]