SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 GLU A 104
ILE A 227
ARG A 233
 FE  A 501 ( 2.4A)
None
None
 0.81A 1cd2A-4p1cA:
undetectable		 1cd2A-4p1cA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 1.01A 1gfzA-4p1cA:
undetectable		 1gfzA-4p1cA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ALA A 489
VAL A 350
TRP A 336
 None
 0.74A 1grmA-4p1cA:
undetectable		 1grmA-4p1cA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ALA A 489
VAL A 350
TRP A 336
 None
 0.74A 1grmB-4p1cA:
undetectable		 1grmB-4p1cA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ALA A 489
VAL A 350
TRP A 336
 None
 0.85A 1jo4A-4p1cA:
undetectable		 1jo4A-4p1cA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ALA A 489
VAL A 350
TRP A 336
 None
 0.85A 1jo4B-4p1cA:
undetectable		 1jo4B-4p1cA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 1.05A 1l5qA-4p1cA:
undetectable		 1l5qA-4p1cA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 1.01A 1l7xA-4p1cA:
undetectable		 1l7xA-4p1cA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 1.03A 1l7xB-4p1cA:
undetectable		 1l7xB-4p1cA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ALA A 489
VAL A 350
TRP A 336
 None
 0.89A 1magA-4p1cA:
undetectable		 1magA-4p1cA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ALA A 489
VAL A 350
TRP A 336
 None
 0.89A 1magB-4p1cA:
undetectable		 1magB-4p1cA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 TRP A 357
HIS A 329
TYR A 362
GLY A 364
 None
 1.39A 1mxdA-4p1cA:
undetectable		 1mxdA-4p1cA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 4 ILE A 246
LEU A 242
VAL A 258
ALA A 265
 None
 0.97A 1mz9A-4p1cA:
undetectable		 1mz9A-4p1cA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 5 ILE A 246
LEU A 242
VAL A 258
ALA A 265
 None
 0.90A 1mz9C-4p1cA:
undetectable		 1mz9C-4p1cA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ALA A 489
VAL A 350
TRP A 336
 None
 0.96A 1nrmB-4p1cA:
undetectable		 1nrmB-4p1cA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		6 / 11 GLU A 134
HIS A 137
LEU A 192
GLU A 197
ILE A 227
GLU A 231
 FE  A 501 (-2.5A)
FE  A 501 (-3.2A)
None
FE  A 502 ( 2.6A)
None
FE  A 502 (-2.3A)
 1.43A 1rnrA-4p1cA:
15.3		 1rnrA-4p1cA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		6 / 12 GLU A 134
HIS A 137
GLU A 197
PHE A 205
ILE A 227
GLU A 231
 FE  A 501 (-2.5A)
FE  A 501 (-3.2A)
FE  A 502 ( 2.6A)
None
None
FE  A 502 (-2.3A)
 1.45A 1rnrB-4p1cA:
15.1		 1rnrB-4p1cA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 12 ALA A 107
HIS A 234
GLU A 134
HIS A 137
GLU A 231
 PEG  A 503 ( 4.1A)
FE  A 502 (-3.5A)
FE  A 501 (-2.5A)
FE  A 501 (-3.2A)
FE  A 502 (-2.3A)
 1.23A 2c6nA-4p1cA:
undetectable		 2c6nA-4p1cA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 11 ILE A 180
GLU A 104
GLY A 130
GLU A 111
GLY A 110
 None
FE  A 501 ( 2.4A)
None
None
None
 1.41A 2fn1B-4p1cA:
undetectable		 2fn1B-4p1cA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 LEU A 393
PRO A 394
ARG A 453
 None
 0.63A 2qd5A-4p1cA:
undetectable		 2qd5A-4p1cA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_D_B49D1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		6 / 10 ILE A 190
VAL A 258
ALA A 254
LEU A 245
GLY A 239
LEU A 309
 None
 0.98A 2y7jD-4p1cA:
undetectable		 2y7jD-4p1cA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_1
(HYPOTHETICAL PROTEIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina;
Pseudomonas
mendocina) 		4 / 4 GLY A 138
GLU A 104
ASP A 230
TYR B  80
 None
FE  A 501 ( 2.4A)
None
None
 1.34A 2yvlC-4p1cA:
undetectable		 2yvlC-4p1cA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 5 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 1.04A 3bcrA-4p1cA:
undetectable		 3bcrA-4p1cA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 GLU A 354
HIS A 329
HIS A 332
 None
 0.78A 3co4A-4p1cA:
undetectable		 3co4A-4p1cA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 0.99A 3dd1B-4p1cA:
undetectable		 3dd1B-4p1cA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 1.01A 3ddwA-4p1cA:
undetectable		 3ddwA-4p1cA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 PHE A 155
ALA A 158
GLY A  98
TYR A  97
 None
 1.03A 3ddwB-4p1cA:
undetectable		 3ddwB-4p1cA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 SER A 289
GLN A 288
PHE A 293
 None
 0.80A 3g4lC-4p1cA:
undetectable		 3g4lC-4p1cA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 12 GLU A 197
GLY A 103
ALA A 107
PHE A 175
ALA A 172
 FE  A 502 ( 2.6A)
PEG  A 503 ( 4.5A)
PEG  A 503 ( 4.1A)
None
None
 1.27A 3nmuA-4p1cA:
undetectable
3nmuF-4p1cA:
undetectable		 3nmuA-4p1cA:
22.14
3nmuF-4p1cA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_B_GLYB511_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 5 SER A  46
GLU A 247
LEU A 244
GLN A 243
 None
 0.95A 3pgyB-4p1cA:
undetectable		 3pgyB-4p1cA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 6 ILE A 170
VAL A 396
LEU A 404
ILE A 402
CYH A 397
 None
 1.41A 4asdA-4p1cA:
undetectable		 4asdA-4p1cA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina) 		3 / 3 ARG B 200
ARG B 187
TRP B 190
 None
 1.18A 4b7nA-4p1cB:
undetectable		 4b7nA-4p1cB:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina) 		3 / 3 ARG B 200
ARG B 187
TRP B 190
 None
 1.16A 4cpzC-4p1cB:
undetectable		 4cpzC-4p1cB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina) 		3 / 3 ARG B 200
ARG B 187
TRP B 190
 None
 1.12A 4cpzE-4p1cB:
undetectable		 4cpzE-4p1cB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina) 		3 / 3 ARG B 200
ARG B 187
TRP B 190
 None
 1.11A 4cpzF-4p1cB:
undetectable		 4cpzF-4p1cB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina) 		3 / 3 ARG B 200
ARG B 187
TRP B 190
 None
 1.15A 4cpzG-4p1cB:
undetectable		 4cpzG-4p1cB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina) 		3 / 3 ARG B 200
ARG B 187
TRP B 190
 None
 1.14A 4cpzH-4p1cB:
undetectable		 4cpzH-4p1cB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina) 		4 / 8 THR A 181
GLY A 110
GLN B 140
ILE A 180
 None
 0.99A 4e1vE-4p1cA:
undetectable		 4e1vE-4p1cA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 12 GLY A 274
THR A 273
LEU A 272
TYR A 331
VAL A 335
 None
 1.12A 4f84A-4p1cA:
undetectable		 4f84A-4p1cA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 PRO A 403
TYR A 331
GLY A 334
 None
 0.72A 4g2zA-4p1cA:
undetectable		 4g2zA-4p1cA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 5 PHE A 269
THR A 198
PHE A 196
ILE A 298
 None
 1.13A 4jx1E-4p1cA:
undetectable		 4jx1E-4p1cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 12 LEU A 393
PRO A 403
ALA A 171
ILE A 459
GLY A 457
 None
 1.37A 4l9qA-4p1cA:
undetectable		 4l9qA-4p1cA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina;
Pseudomonas
mendocina) 		3 / 3 HIS B 165
TRP A   9
SER B 253
 None
 1.19A 4lrhD-4p1cB:
undetectable		 4lrhD-4p1cB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 7 ILE A 186
LEU A 245
TYR A  47
GLY A 238
 None
 1.03A 4z69A-4p1cA:
1.5		 4z69A-4p1cA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 5 VAL A 407
ILE A 459
PRO A 403
THR A 340
 None
 1.17A 4ze1A-4p1cA:
undetectable		 4ze1A-4p1cA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 8 GLY A 409
TRP A 365
TYR A 362
GLY A 370
 None
 0.80A 5albL-4p1cA:
undetectable		 5albL-4p1cA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ASP A  48
ASN A 123
PHE A 129
 None
 0.77A 5dsgB-4p1cA:
undetectable		 5dsgB-4p1cA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 ILE A 227
PHE A 220
THR A  92
TRP A  89
 None
 1.09A 5g08A-4p1cA:
undetectable		 5g08A-4p1cA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina) 		4 / 5 ILE B 282
PHE B 216
SER B 265
ALA B 272
 None
 1.20A 5msdA-4p1cB:
undetectable		 5msdA-4p1cB:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 12 ILE A 402
PHE A 428
VAL A 416
ILE A 170
ALA A 171
 None
 1.16A 5n0sB-4p1cA:
undetectable		 5n0sB-4p1cA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 8 ARG A 136
GLU A 134
GLY A 138
LEU A 140
 None
FE  A 501 (-2.5A)
None
None
 0.98A 5sxqB-4p1cA:
0.4		 5sxqB-4p1cA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 8 ARG A 136
GLU A 134
GLY A 138
LEU A 140
 None
FE  A 501 (-2.5A)
None
None
 1.00A 5syjA-4p1cA:
undetectable		 5syjA-4p1cA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 7 PHE A 220
ASP A 211
LEU A 208
SER A  95
 None
 1.25A 5uxcA-4p1cA:
undetectable		 5uxcA-4p1cA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN E
(Pseudomonas
mendocina;
Pseudomonas
mendocina) 		4 / 6 CYH B 151
SER B 149
HIS B  33
TYR A 105
 None
 1.43A 5ycnA-4p1cB:
undetectable		 5ycnA-4p1cB:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 9 TYR A  47
ASP A  48
ALA A 235
GLY A 122
GLY A 238
 None
 1.35A 6awoA-4p1cA:
undetectable		 6awoA-4p1cA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		5 / 9 TYR A  47
ASP A  48
ALA A 235
GLY A 122
GLY A 238
 None
 1.36A 6awqA-4p1cA:
3.1		 6awqA-4p1cA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		3 / 3 ARG A 264
ARG A 183
ASP A 178
 None
 0.98A 6d8pA-4p1cA:
undetectable		 6d8pA-4p1cA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 TRP A 263
MET A 294
GLY A 199
ALA A 265
 None
 0.90A 6fosA-4p1cA:
1.8		 6fosA-4p1cA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A
(Pseudomonas
mendocina) 		4 / 6 TRP A 357
GLY A 370
TRP A 373
LEU A 358
 None
 1.09A 6fosA-4p1cA:
1.8		 6fosA-4p1cA:
11.49