SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4p1z PIWI-LIKE PROTEIN 1
(Mus
musculus) 		5 / 12 ALA A 530
ILE A 513
LEU A 512
LEU A 560
VAL A 587
 None
 1.22A 3adsB-4p1zA:
undetectable		 3adsB-4p1zA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 4p1z PIWI-LIKE PROTEIN 1
(Mus
musculus) 		5 / 10 ALA A 602
LEU A 512
ASN A 515
LEU A 516
VAL A 519
 None
 0.75A 3o02A-4p1zA:
undetectable
3o02B-4p1zA:
undetectable		 3o02A-4p1zA:
20.97
3o02B-4p1zA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 4p1z PIWI-LIKE PROTEIN 1
(Mus
musculus) 		3 / 3 LEU A 607
LYS A 604
THR A 603
 None
 0.63A 4lj0A-4p1zA:
undetectable		 4lj0A-4p1zA:
16.39