SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p2k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		3 / 3 ARG A 816
ILE A 805
TRP A 783
 None
 1.23A 1m8eB-4p2kA:
undetectable		 1m8eB-4p2kA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		3 / 3 ARG A 816
ILE A 805
TRP A 783
 None
 1.17A 1qomA-4p2kA:
undetectable		 1qomA-4p2kA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		4 / 7 ASN A 744
HIS A 737
PHE A 758
ILE A 723
 None
 1.22A 1tdnA-4p2kA:
undetectable		 1tdnA-4p2kA:
19.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 VAL A 627
ALA A 644
ILE A 666
ILE A 690
THR A 692
ASP A 757
 None
 1.29A 2hyyD-4p2kA:
31.9		 2hyyD-4p2kA:
38.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 VAL A 627
ALA A 644
ILE A 666
ILE A 690
THR A 692
LEU A 746
 None
 1.03A 2hyyD-4p2kA:
31.9		 2hyyD-4p2kA:
38.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ITY_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		9 / 12 GLY A 620
VAL A 627
ALA A 644
GLU A 663
MET A 667
THR A 692
GLY A 698
LEU A 746
ASP A 757
 None
 0.97A 2ityA-4p2kA:
34.4		 2ityA-4p2kA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		4 / 7 THR A 784
ILE A 830
ASN A 831
GLN A 856
 None
 0.98A 2jc9A-4p2kA:
undetectable		 2jc9A-4p2kA:
22.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
MET A 667
ILE A 690
THR A 692
TYR A 694
ASP A 757
 None
 0.77A 2oiqA-4p2kA:
32.4		 2oiqA-4p2kA:
43.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 GLY A 620
VAL A 627
ALA A 644
TYR A 694
MET A 695
GLY A 698
 None
 0.69A 2wgjA-4p2kA:
31.4		 2wgjA-4p2kA:
36.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 VAL A 627
ALA A 644
TYR A 694
MET A 695
GLY A 698
ASP A 757
 None
 0.74A 2wgjA-4p2kA:
31.4		 2wgjA-4p2kA:
36.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 9 VAL A 627
ALA A 644
MET A 695
GLY A 698
LEU A 746
ASP A 757
 None
 0.61A 2xp2A-4p2kA:
35.0		 2xp2A-4p2kA:
36.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		10 / 12 LYS A 617
ILE A 619
ALA A 644
GLU A 663
ILE A 690
THR A 692
TYR A 694
GLY A 698
LEU A 746
SER A 756
 None
 0.97A 2y6oA-4p2kA:
37.1		 2y6oA-4p2kA:
74.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		10 / 12 LYS A 617
ILE A 619
ALA A 644
GLU A 663
MET A 667
ILE A 690
THR A 692
TYR A 694
LEU A 746
SER A 756
 None
 1.09A 2y6oA-4p2kA:
37.1		 2y6oA-4p2kA:
74.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 LYS A 617
ILE A 619
LYS A 646
GLU A 663
MET A 667
ILE A 690
TYR A 694
 None
 1.34A 2y6oA-4p2kA:
37.1		 2y6oA-4p2kA:
74.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_A_B49A1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 ALA A 644
ILE A 676
MET A 695
GLY A 698
LEU A 746
ASP A 757
 None
 0.58A 2y7jA-4p2kA:
26.3		 2y7jA-4p2kA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_A_B49A1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 ILE A 619
VAL A 627
ALA A 644
ILE A 676
MET A 695
GLY A 698
LEU A 746
 None
 0.74A 2y7jA-4p2kA:
26.3		 2y7jA-4p2kA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_B_B49B1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 10 ALA A 644
ILE A 676
MET A 695
GLY A 698
LEU A 746
ASP A 757
 None
 0.59A 2y7jB-4p2kA:
26.9		 2y7jB-4p2kA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_B_B49B1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 10 ILE A 619
VAL A 627
ALA A 644
ILE A 676
MET A 695
GLY A 698
LEU A 746
 None
 0.64A 2y7jB-4p2kA:
26.9		 2y7jB-4p2kA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_C_B49C1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 10 ILE A 619
VAL A 627
ALA A 644
ILE A 676
MET A 695
GLY A 698
LEU A 746
 None
 0.69A 2y7jC-4p2kA:
26.4		 2y7jC-4p2kA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_D_B49D1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 10 ILE A 619
VAL A 627
ALA A 644
ILE A 676
MET A 695
GLY A 698
LEU A 746
 None
 0.61A 2y7jD-4p2kA:
26.7		 2y7jD-4p2kA:
24.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZVA_A_1N1A513_1
(TYROSINE-PROTEIN
KINASE LYN)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 ALA A 644
GLU A 663
MET A 667
ILE A 690
THR A 692
MET A 695
GLY A 698
LEU A 746
 None
 0.89A 2zvaA-4p2kA:
36.0		 2zvaA-4p2kA:
40.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BBT_B_FMMB91_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 VAL A 627
ALA A 644
LEU A 678
THR A 692
GLY A 698
LEU A 746
 None
 0.61A 3bbtB-4p2kA:
29.9		 3bbtB-4p2kA:
35.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0F_B_B49B9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 10 VAL A 627
ALA A 644
THR A 692
TYR A 694
GLY A 698
LEU A 746
 None
 0.81A 3g0fB-4p2kA:
30.6		 3g0fB-4p2kA:
32.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 12 VAL A 627
ALA A 644
GLU A 663
ILE A 676
THR A 692
 None
 1.03A 3gcsA-4p2kA:
9.5		 3gcsA-4p2kA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 VAL A 627
ALA A 644
GLU A 663
ILE A 676
THR A 692
ASP A 757
 None
 1.19A 3gp0A-4p2kA:
19.7		 3gp0A-4p2kA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 12 ASP A 799
ARG A 861
ALA A 785
GLU A 787
ARG A 762
 None
 1.38A 3k39D-4p2kA:
undetectable		 3k39D-4p2kA:
21.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 ALA A 644
GLU A 663
MET A 667
ILE A 690
THR A 692
TYR A 694
GLY A 698
LEU A 746
 None
 0.96A 3k54A-4p2kA:
27.8		 3k54A-4p2kA:
39.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 ALA A 644
ILE A 690
THR A 692
TYR A 694
GLY A 698
LEU A 746
SER A 756
 None
 0.53A 3k54A-4p2kA:
27.8		 3k54A-4p2kA:
39.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_A_B49A1_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 11 ILE A 619
ALA A 644
MET A 695
GLY A 698
LEU A 746
SER A 756
 None
 0.69A 3miyA-4p2kA:
34.0		 3miyA-4p2kA:
38.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_B_B49B2_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 9 ILE A 619
ALA A 644
LYS A 646
MET A 695
GLY A 698
LEU A 746
SER A 756
 None
 0.86A 3miyB-4p2kA:
33.9		 3miyB-4p2kA:
38.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		3 / 3 ARG A 816
ILE A 805
TRP A 783
 None
 1.04A 3nw2A-4p2kA:
undetectable		 3nw2A-4p2kA:
20.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
GLU A 663
MET A 667
ILE A 690
THR A 692
TYR A 694
 None
 0.87A 3oezB-4p2kA:
32.4		 3oezB-4p2kA:
43.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 GLY A 620
VAL A 627
ALA A 644
ILE A 676
THR A 692
LEU A 746
 None
 0.96A 3ohtA-4p2kA:
16.9		 3ohtA-4p2kA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_1
(P38A)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 GLY A 620
VAL A 627
ALA A 644
ILE A 676
THR A 692
LEU A 746
 None
 0.96A 3ohtB-4p2kA:
6.1		 3ohtB-4p2kA:
25.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_B_1N1B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 VAL A 627
ALA A 644
GLU A 663
MET A 667
THR A 692
TYR A 694
GLY A 698
LEU A 746
 None
 1.02A 3qlgB-4p2kA:
33.8		 3qlgB-4p2kA:
43.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
ILE A 690
THR A 692
TYR A 694
GLY A 698
LEU A 746
 None
 0.57A 3sxrA-4p2kA:
33.4		 3sxrA-4p2kA:
38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
MET A 667
ILE A 690
THR A 692
TYR A 694
SER A 756
 None
 0.55A 3sxrA-4p2kA:
33.4		 3sxrA-4p2kA:
38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
MET A 667
THR A 692
TYR A 694
GLY A 698
LEU A 746
 None
 0.80A 3sxrB-4p2kA:
33.0		 3sxrB-4p2kA:
38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UE4_A_DB8A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 ALA A 644
ILE A 690
THR A 692
MET A 695
GLY A 698
LEU A 746
 None
 0.39A 3ue4A-4p2kA:
34.0		 3ue4A-4p2kA:
38.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ACTA908_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		4 / 4 MET A 688
SER A 683
LEU A 661
VAL A 681
 None
 1.39A 3vlnA-4p2kA:
0.4		 3vlnA-4p2kA:
21.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 9 ILE A 666
ILE A 675
ILE A 676
TYR A 694
MET A 695
 None
 0.74A 3zosA-4p2kA:
30.0		 3zosA-4p2kA:
36.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 9 MET A 667
ILE A 675
ILE A 676
TYR A 694
MET A 695
 None
 0.92A 3zosA-4p2kA:
30.0		 3zosA-4p2kA:
36.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 9 VAL A 627
ALA A 644
MET A 695
GLY A 698
LEU A 746
ASP A 757
 None
 0.54A 4anqA-4p2kA:
34.6		 4anqA-4p2kA:
36.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 9 VAL A 627
ALA A 644
MET A 695
GLY A 698
LEU A 746
ASP A 757
 None
 0.50A 4ansA-4p2kA:
34.5		 4ansA-4p2kA:
36.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 ALA A 644
GLU A 663
ILE A 666
ILE A 676
THR A 692
TYR A 694
ASP A 757
 None
 1.09A 4bkjA-4p2kA:
30.3		 4bkjA-4p2kA:
36.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 ALA A 644
GLU A 663
MET A 667
ILE A 676
THR A 692
TYR A 694
ASP A 757
 None
 1.13A 4bkjA-4p2kA:
30.3		 4bkjA-4p2kA:
36.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
MET A 667
ILE A 676
THR A 692
TYR A 694
ASP A 757
 None
 0.89A 4bkjA-4p2kA:
30.3		 4bkjA-4p2kA:
36.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
MET A 667
ILE A 676
THR A 692
TYR A 694
LEU A 746
 None
 1.27A 4bkjA-4p2kA:
30.3		 4bkjA-4p2kA:
36.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		3 / 3 TYR A 694
MET A 695
ILE A 675
 None
 0.82A 4c8bB-4p2kA:
27.0		 4c8bB-4p2kA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		3 / 3 TYR A 694
MET A 695
ILE A 745
 None
 0.88A 4c8bB-4p2kA:
27.0		 4c8bB-4p2kA:
28.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
GLU A 663
MET A 667
THR A 692
TYR A 694
ASP A 757
 None
 1.12A 4csvA-4p2kA:
32.9		 4csvA-4p2kA:
43.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HJO_A_AQ4A1001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 VAL A 627
ALA A 644
THR A 692
MET A 695
GLY A 698
LEU A 746
 None
 0.47A 4hjoA-4p2kA:
30.4		 4hjoA-4p2kA:
34.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 ALA A 644
GLU A 663
MET A 667
ILE A 690
THR A 692
TYR A 694
GLY A 698
ASP A 757
 None
 0.91A 4mxoA-4p2kA:
34.9		 4mxoA-4p2kA:
44.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 VAL A 627
ALA A 644
MET A 667
ILE A 690
THR A 692
TYR A 694
GLY A 698
ASP A 757
 None
 0.68A 4mxoA-4p2kA:
34.9		 4mxoA-4p2kA:
44.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXO_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 VAL A 627
ALA A 644
ILE A 690
THR A 692
TYR A 694
GLY A 698
LEU A 746
ASP A 757
 None
 0.58A 4mxoB-4p2kA:
35.0		 4mxoB-4p2kA:
44.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 ALA A 644
GLU A 663
MET A 667
ILE A 690
THR A 692
TYR A 694
GLY A 698
LEU A 746
 None
 0.86A 4mxxA-4p2kA:
34.8		 4mxxA-4p2kA:
44.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
THR A 692
TYR A 694
MET A 695
GLY A 698
LEU A 746
 None
 0.40A 4mxxB-4p2kA:
32.3		 4mxxB-4p2kA:
44.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 8 ILE A 619
GLY A 622
VAL A 627
ALA A 644
LEU A 746
 None
 0.43A 4ogrA-4p2kA:
25.3		 4ogrA-4p2kA:
25.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QMN_A_DB8A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 ILE A 619
ALA A 644
GLU A 663
ILE A 690
TYR A 694
LEU A 746
ASP A 757
 None
 0.97A 4qmnA-4p2kA:
21.7		 4qmnA-4p2kA:
30.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QMZ_A_B49A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 ILE A 619
GLY A 620
VAL A 627
ALA A 644
TYR A 694
LEU A 746
 None
 0.43A 4qmzA-4p2kA:
29.0		 4qmzA-4p2kA:
30.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 9 VAL A 627
ALA A 644
TYR A 694
MET A 695
GLY A 698
LEU A 746
ASP A 757
 None
 0.51A 4u5jB-4p2kA:
34.1		 4u5jB-4p2kA:
43.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_A_AXIA9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 11 ALA A 644
THR A 692
MET A 695
GLY A 698
ASN A 744
LEU A 746
 None
 0.42A 4wa9A-4p2kA:
29.8		 4wa9A-4p2kA:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
THR A 692
MET A 695
GLY A 698
ASN A 744
LEU A 746
 None
 0.85A 4wa9B-4p2kA:
32.6		 4wa9B-4p2kA:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 ALA A 644
GLU A 663
MET A 667
ILE A 690
THR A 692
TYR A 694
GLY A 698
LEU A 746
 None
 0.98A 4xliB-4p2kA:
34.2		 4xliB-4p2kA:
39.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		4 / 6 ALA A 644
LYS A 646
MET A 695
LEU A 746
 None
 0.81A 4xoyA-4p2kA:
9.5		 4xoyA-4p2kA:
26.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 9 VAL A 627
ALA A 644
MET A 695
GLY A 698
LEU A 746
ASP A 757
 None
 0.66A 5aaaA-4p2kA:
35.0		 5aaaA-4p2kA:
36.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_A_1N1A501_1
(PROTEIN-TYROSINE
KINASE 6)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 12 VAL A 627
ALA A 644
THR A 692
GLY A 698
LEU A 746
 None
 0.45A 5h2uA-4p2kA:
30.1		 5h2uA-4p2kA:
38.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 VAL A 627
ALA A 644
ILE A 676
ILE A 690
THR A 692
TYR A 694
 None
 0.55A 5hesA-4p2kA:
10.7		 5hesA-4p2kA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 12 VAL A 627
ALA A 644
ILE A 690
THR A 692
TYR A 694
 None
 0.45A 5hesB-4p2kA:
23.8		 5hesB-4p2kA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 12 GLY A 622
VAL A 627
ALA A 644
ILE A 690
THR A 692
 None
 0.71A 5hieA-4p2kA:
26.7		 5hieA-4p2kA:
33.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 12 GLY A 622
VAL A 627
ALA A 644
ILE A 690
THR A 692
 None
 0.73A 5hieB-4p2kA:
26.7		 5hieB-4p2kA:
33.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 12 GLY A 622
VAL A 627
ALA A 644
ILE A 690
THR A 692
 None
 0.72A 5hieD-4p2kA:
26.9		 5hieD-4p2kA:
33.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		9 / 12 ILE A 619
ALA A 644
ILE A 676
ILE A 690
THR A 692
TYR A 694
GLY A 698
GLU A 706
LEU A 746
 None
 0.66A 5i9xA-4p2kA:
36.3		 5i9xA-4p2kA:
94.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 ILE A 619
ALA A 644
ILE A 676
TYR A 694
GLY A 698
LEU A 746
SER A 756
 None
 0.66A 5i9xA-4p2kA:
36.3		 5i9xA-4p2kA:
94.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 ILE A 619
GLU A 663
ILE A 676
ILE A 690
THR A 692
GLY A 698
LEU A 746
 None
 0.96A 5i9xA-4p2kA:
36.3		 5i9xA-4p2kA:
94.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		9 / 12 ILE A 619
ALA A 644
GLU A 663
MET A 667
THR A 692
TYR A 694
GLY A 698
LEU A 746
SER A 756
 None
 0.97A 5i9yA-4p2kA:
35.7		 5i9yA-4p2kA:
94.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		9 / 12 ILE A 619
ALA A 644
LYS A 646
GLU A 663
MET A 667
TYR A 694
GLY A 698
LEU A 746
SER A 756
 None
 1.16A 5i9yA-4p2kA:
35.7		 5i9yA-4p2kA:
94.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		9 / 12 ILE A 619
ALA A 644
LYS A 646
MET A 667
TYR A 694
GLY A 698
GLU A 706
LEU A 746
SER A 756
 None
 1.17A 5i9yA-4p2kA:
35.7		 5i9yA-4p2kA:
94.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		9 / 12 ILE A 619
ALA A 644
MET A 667
THR A 692
TYR A 694
GLY A 698
GLU A 706
LEU A 746
SER A 756
 None
 0.93A 5i9yA-4p2kA:
35.7		 5i9yA-4p2kA:
94.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		4 / 6 GLY A 814
ASP A 739
ILE A 781
ARG A 782
 None
 1.04A 5iwuA-4p2kA:
7.8		 5iwuA-4p2kA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 9 ILE A 619
GLY A 620
VAL A 627
ALA A 644
ILE A 676
LEU A 746
 None
 1.33A 5lw1B-4p2kA:
21.0		 5lw1B-4p2kA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 9 ILE A 619
GLY A 620
VAL A 627
ALA A 644
ILE A 676
MET A 695
 None
 0.71A 5lw1B-4p2kA:
21.0		 5lw1B-4p2kA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_1
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		8 / 12 ILE A 619
GLY A 620
VAL A 627
ALA A 644
LYS A 646
GLU A 663
TYR A 694
GLY A 698
 None
 1.13A 5mafA-4p2kA:
26.1		 5mafA-4p2kA:
15.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5P9I_A_1E8A701_1
(TYROSINE-PROTEIN
KINASE BTK)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 GLY A 622
VAL A 627
ALA A 644
ILE A 690
THR A 692
LEU A 746
SER A 756
 None
 0.65A 5p9iA-4p2kA:
32.0		 5p9iA-4p2kA:
40.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5P9I_A_1E8A701_1
(TYROSINE-PROTEIN
KINASE BTK)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
ILE A 690
THR A 692
GLY A 698
LEU A 746
SER A 756
 None
 0.32A 5p9iA-4p2kA:
32.0		 5p9iA-4p2kA:
40.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_1
(WEE1-LIKE PROTEIN
KINASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 ILE A 619
GLY A 620
ALA A 644
GLU A 663
TYR A 694
ASP A 757
 None
 0.82A 5vc3A-4p2kA:
25.5		 5vc3A-4p2kA:
25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_1
(WEE1-LIKE PROTEIN
KINASE)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		6 / 12 ILE A 619
GLY A 620
ALA A 644
GLU A 663
TYR A 694
GLY A 698
 None
 0.92A 5vc3A-4p2kA:
25.5		 5vc3A-4p2kA:
25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		3 / 3 TYR A 694
LEU A 746
ASP A 757
 None
 0.58A 5zv2B-4p2kA:
31.5		 5zv2B-4p2kA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		7 / 12 VAL A 627
ALA A 644
THR A 692
TYR A 694
MET A 695
GLY A 698
LEU A 746
 None
 0.58A 6bsdA-4p2kA:
31.2		 6bsdA-4p2kA:
12.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FNM_A_1N1A1001_1
(-)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		10 / 12 ILE A 619
VAL A 627
ALA A 644
GLU A 663
MET A 667
ILE A 690
THR A 692
MET A 695
GLY A 698
LEU A 746
 None
 0.78A 6fnmA-4p2kA:
37.5		 6fnmA-4p2kA:
65.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FNM_A_1N1A1001_1
(-)		 4p2k EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		9 / 12 ILE A 619
VAL A 627
ALA A 644
GLU A 663
THR A 692
MET A 695
GLY A 698
LEU A 746
SER A 756
 None
 0.88A 6fnmA-4p2kA:
37.5		 6fnmA-4p2kA:
65.56