SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p2l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		5 / 12 PHE A 406
LEU A 333
PHE A 374
GLY A 320
GLY A 451
 None
 1.11A 1fe2A-4p2lA:
0.0		 1fe2A-4p2lA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 5 PHE A 116
GLY A 134
SER A 131
PHE A 127
 None
 1.38A 1icuC-4p2lA:
undetectable
1icuD-4p2lA:
undetectable		 1icuC-4p2lA:
19.84
1icuD-4p2lA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 1k2rA-4p2lA:
undetectable
1k2rB-4p2lA:
undetectable		 1k2rA-4p2lA:
21.14
1k2rB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 1k2rA-4p2lA:
undetectable
1k2rB-4p2lA:
undetectable		 1k2rA-4p2lA:
21.14
1k2rB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.31A 1k2tA-4p2lA:
undetectable
1k2tB-4p2lA:
undetectable		 1k2tA-4p2lA:
21.14
1k2tB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 1k2tA-4p2lA:
undetectable
1k2tB-4p2lA:
undetectable		 1k2tA-4p2lA:
21.14
1k2tB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 1k2uA-4p2lA:
undetectable
1k2uB-4p2lA:
undetectable		 1k2uA-4p2lA:
21.14
1k2uB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 SER A 425
ALA A 421
TYR A 343
ALA A 433
 None
 1.04A 1k5qA-4p2lA:
undetectable
1k5qB-4p2lA:
undetectable		 1k5qA-4p2lA:
17.93
1k5qB-4p2lA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 1lzxA-4p2lA:
undetectable
1lzxB-4p2lA:
undetectable		 1lzxA-4p2lA:
21.14
1lzxB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 1lzxA-4p2lA:
undetectable
1lzxB-4p2lA:
undetectable		 1lzxA-4p2lA:
21.14
1lzxB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.26A 1lzzA-4p2lA:
undetectable
1lzzB-4p2lA:
undetectable		 1lzzA-4p2lA:
21.14
1lzzB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.27A 1lzzA-4p2lA:
undetectable
1lzzB-4p2lA:
undetectable		 1lzzA-4p2lA:
21.14
1lzzB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 1m00A-4p2lA:
undetectable
1m00B-4p2lA:
undetectable		 1m00A-4p2lA:
21.14
1m00B-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 1mmvA-4p2lA:
undetectable
1mmvB-4p2lA:
undetectable		 1mmvA-4p2lA:
21.14
1mmvB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 1mmvA-4p2lA:
undetectable
1mmvB-4p2lA:
undetectable		 1mmvA-4p2lA:
21.14
1mmvB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.27A 1mmwA-4p2lA:
undetectable
1mmwB-4p2lA:
undetectable		 1mmwA-4p2lA:
21.14
1mmwB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.26A 1mmwA-4p2lA:
undetectable
1mmwB-4p2lA:
undetectable		 1mmwA-4p2lA:
21.14
1mmwB-4p2lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.30A 1om4A-4p2lA:
0.0
1om4B-4p2lA:
undetectable		 1om4A-4p2lA:
21.63
1om4B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 1p6jA-4p2lA:
undetectable
1p6jB-4p2lA:
undetectable		 1p6jA-4p2lA:
21.43
1p6jB-4p2lA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 1p6kA-4p2lA:
undetectable
1p6kB-4p2lA:
undetectable		 1p6kA-4p2lA:
21.43
1p6kB-4p2lA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 1p6kA-4p2lA:
undetectable
1p6kB-4p2lA:
undetectable		 1p6kA-4p2lA:
21.43
1p6kB-4p2lA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 8 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 1rs6A-4p2lA:
undetectable
1rs6B-4p2lA:
undetectable		 1rs6A-4p2lA:
21.43
1rs6B-4p2lA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.33A 1rs7A-4p2lA:
undetectable
1rs7B-4p2lA:
undetectable		 1rs7A-4p2lA:
21.43
1rs7B-4p2lA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		3 / 3 ALA A 489
VAL A 504
TRP A 506
 None
None
FAD  A 601 (-3.5A)
 0.75A 1tkqB-4p2lA:
undetectable		 1tkqB-4p2lA:
3.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.26A 1zzrA-4p2lA:
undetectable
1zzrB-4p2lA:
undetectable		 1zzrA-4p2lA:
21.34
1zzrB-4p2lA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 8 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 2g6hA-4p2lA:
undetectable
2g6hB-4p2lA:
undetectable		 2g6hA-4p2lA:
21.34
2g6hB-4p2lA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.26A 2g6kA-4p2lA:
undetectable
2g6kB-4p2lA:
undetectable		 2g6kA-4p2lA:
21.34
2g6kB-4p2lA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.27A 2hx3A-4p2lA:
undetectable
2hx3B-4p2lA:
undetectable		 2hx3A-4p2lA:
21.63
2hx3B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.30A 2hx4A-4p2lA:
undetectable
2hx4B-4p2lA:
undetectable		 2hx4A-4p2lA:
21.63
2hx4B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 3b3mA-4p2lA:
undetectable
3b3mB-4p2lA:
undetectable		 3b3mA-4p2lA:
21.63
3b3mB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.32A 3b3nA-4p2lA:
undetectable
3b3nB-4p2lA:
undetectable		 3b3nA-4p2lA:
21.63
3b3nB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 3b3nA-4p2lA:
undetectable
3b3nB-4p2lA:
undetectable		 3b3nA-4p2lA:
21.63
3b3nB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 3b3oA-4p2lA:
undetectable
3b3oB-4p2lA:
undetectable		 3b3oA-4p2lA:
21.63
3b3oB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 3b3oA-4p2lA:
undetectable
3b3oB-4p2lA:
undetectable		 3b3oA-4p2lA:
21.63
3b3oB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.35A 3b3pA-4p2lA:
undetectable
3b3pB-4p2lA:
undetectable		 3b3pA-4p2lA:
21.63
3b3pB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		3 / 3 ARG A 274
VAL A 206
THR A 263
 None
 0.85A 3cyxA-4p2lA:
undetectable		 3cyxA-4p2lA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.27A 3dqrA-4p2lA:
undetectable
3dqrB-4p2lA:
undetectable		 3dqrA-4p2lA:
21.63
3dqrB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.33A 3dqrA-4p2lA:
undetectable
3dqrB-4p2lA:
undetectable		 3dqrA-4p2lA:
21.63
3dqrB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.32A 3fc5A-4p2lA:
undetectable
3fc5B-4p2lA:
undetectable		 3fc5A-4p2lA:
21.63
3fc5B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 3fc5A-4p2lA:
undetectable
3fc5B-4p2lA:
undetectable		 3fc5A-4p2lA:
21.63
3fc5B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 GLU A 400
PHE A 403
GLN A 500
PRO A 499
 None
 1.11A 3gclA-4p2lA:
undetectable		 3gclA-4p2lA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.32A 3hsnA-4p2lA:
undetectable
3hsnB-4p2lA:
undetectable		 3hsnA-4p2lA:
21.63
3hsnB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.31A 3hsoA-4p2lA:
undetectable
3hsoB-4p2lA:
undetectable		 3hsoA-4p2lA:
21.63
3hsoB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.31A 3hspA-4p2lA:
undetectable
3hspB-4p2lA:
undetectable		 3hspA-4p2lA:
21.63
3hspB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 3jt3A-4p2lA:
undetectable
3jt3B-4p2lA:
undetectable		 3jt3A-4p2lA:
21.63
3jt3B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.31A 3jt7A-4p2lA:
undetectable
3jt7B-4p2lA:
undetectable		 3jt7A-4p2lA:
21.63
3jt7B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 3jt8A-4p2lA:
undetectable
3jt8B-4p2lA:
undetectable		 3jt8A-4p2lA:
21.63
3jt8B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 3jt9A-4p2lA:
undetectable
3jt9B-4p2lA:
undetectable		 3jt9A-4p2lA:
21.63
3jt9B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 3jtaA-4p2lA:
undetectable
3jtaB-4p2lA:
undetectable		 3jtaA-4p2lA:
21.63
3jtaB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.32A 3jwvA-4p2lA:
undetectable
3jwvB-4p2lA:
undetectable		 3jwvA-4p2lA:
21.63
3jwvB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 3jx2A-4p2lA:
undetectable
3jx2B-4p2lA:
undetectable		 3jx2A-4p2lA:
21.63
3jx2B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.27A 3jx3A-4p2lA:
undetectable
3jx3B-4p2lA:
undetectable		 3jx3A-4p2lA:
21.63
3jx3B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 3jx4A-4p2lA:
undetectable
3jx4B-4p2lA:
undetectable		 3jx4A-4p2lA:
21.63
3jx4B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 3jx5A-4p2lA:
undetectable
3jx5B-4p2lA:
undetectable		 3jx5A-4p2lA:
21.63
3jx5B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.24A 3jx6A-4p2lA:
0.0
3jx6B-4p2lA:
undetectable		 3jx6A-4p2lA:
21.34
3jx6B-4p2lA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		5 / 12 LEU A 311
VAL A 350
GLY A 346
PHE A 416
LEU A 413
 None
 1.21A 3mecA-4p2lA:
undetectable		 3mecA-4p2lA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		5 / 12 LEU A 311
VAL A 350
GLY A 346
PHE A 416
LEU A 413
 None
 1.22A 3medA-4p2lA:
undetectable
3medB-4p2lA:
undetectable		 3medA-4p2lA:
21.78
3medB-4p2lA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.22A 3n5vA-4p2lA:
undetectable
3n5vB-4p2lA:
undetectable		 3n5vA-4p2lA:
21.63
3n5vB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.26A 3n5yA-4p2lA:
undetectable
3n5yB-4p2lA:
undetectable		 3n5yA-4p2lA:
21.63
3n5yB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.26A 3n5zA-4p2lA:
undetectable
3n5zB-4p2lA:
undetectable		 3n5zA-4p2lA:
21.63
3n5zB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 3nljA-4p2lA:
undetectable
3nljB-4p2lA:
undetectable		 3nljA-4p2lA:
21.34
3nljB-4p2lA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 3nlpA-4p2lA:
undetectable
3nlpB-4p2lA:
undetectable		 3nlpA-4p2lA:
21.63
3nlpB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.30A 3nlwA-4p2lA:
undetectable
3nlwB-4p2lA:
undetectable		 3nlwA-4p2lA:
21.63
3nlwB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.30A 3nnzA-4p2lA:
undetectable
3nnzB-4p2lA:
undetectable		 3nnzA-4p2lA:
21.63
3nnzB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 3nnzA-4p2lA:
undetectable
3nnzB-4p2lA:
undetectable		 3nnzA-4p2lA:
21.63
3nnzB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 3pnfA-4p2lA:
undetectable
3pnfB-4p2lA:
undetectable		 3pnfA-4p2lA:
21.63
3pnfB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 3q9aA-4p2lA:
undetectable
3q9aB-4p2lA:
undetectable		 3q9aA-4p2lA:
21.63
3q9aB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 3rqkA-4p2lA:
undetectable
3rqkB-4p2lA:
undetectable		 3rqkA-4p2lA:
21.63
3rqkB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 3svqA-4p2lA:
undetectable
3svqB-4p2lA:
undetectable		 3svqA-4p2lA:
21.63
3svqB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.32A 3tynA-4p2lA:
undetectable
3tynB-4p2lA:
undetectable		 3tynA-4p2lA:
21.63
3tynB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.27A 3ufoA-4p2lA:
undetectable
3ufoB-4p2lA:
undetectable		 3ufoA-4p2lA:
21.63
3ufoB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.34A 3ufpA-4p2lA:
undetectable
3ufpB-4p2lA:
undetectable		 3ufpA-4p2lA:
21.63
3ufpB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.33A 3ufqA-4p2lA:
undetectable
3ufqB-4p2lA:
undetectable		 3ufqA-4p2lA:
21.63
3ufqB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 3ufrA-4p2lA:
undetectable
3ufrB-4p2lA:
undetectable		 3ufrA-4p2lA:
21.63
3ufrB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.31A 3uftA-4p2lA:
undetectable
3uftB-4p2lA:
undetectable		 3uftA-4p2lA:
21.63
3uftB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.32A 3uftA-4p2lA:
undetectable
3uftB-4p2lA:
undetectable		 3uftA-4p2lA:
21.63
3uftB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 3ufuA-4p2lA:
undetectable
3ufuB-4p2lA:
undetectable		 3ufuA-4p2lA:
21.63
3ufuB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 3ufvA-4p2lA:
undetectable
3ufvB-4p2lA:
undetectable		 3ufvA-4p2lA:
21.63
3ufvB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		5 / 12 GLY A 398
PHE A 501
VAL A 412
ASP A 306
TYR A 303
 None
None
FAD  A 601 ( 4.7A)
None
None
 1.18A 4a83A-4p2lA:
undetectable		 4a83A-4p2lA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4caoA-4p2lA:
undetectable
4caoB-4p2lA:
undetectable		 4caoA-4p2lA:
21.63
4caoB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 8 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 4capA-4p2lA:
undetectable
4capB-4p2lA:
undetectable		 4capA-4p2lA:
21.63
4capB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4cdtA-4p2lA:
undetectable
4cdtB-4p2lA:
undetectable		 4cdtA-4p2lA:
21.63
4cdtB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.33A 4cttA-4p2lA:
undetectable
4cttB-4p2lA:
undetectable		 4cttA-4p2lA:
21.63
4cttB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4d2yA-4p2lA:
undetectable
4d2yB-4p2lA:
undetectable		 4d2yA-4p2lA:
21.63
4d2yB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4d31A-4p2lA:
undetectable
4d31B-4p2lA:
undetectable		 4d31A-4p2lA:
21.63
4d31B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 4fvzA-4p2lA:
undetectable
4fvzB-4p2lA:
undetectable		 4fvzA-4p2lA:
21.63
4fvzB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4imtA-4p2lA:
undetectable
4imtB-4p2lA:
undetectable		 4imtA-4p2lA:
21.63
4imtB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.24A 4imwA-4p2lA:
undetectable
4imwB-4p2lA:
undetectable		 4imwA-4p2lA:
21.63
4imwB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4jsfA-4p2lA:
undetectable
4jsfB-4p2lA:
undetectable		 4jsfA-4p2lA:
21.63
4jsfB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.27A 4jshA-4p2lA:
undetectable
4jshB-4p2lA:
undetectable		 4jshA-4p2lA:
21.63
4jshB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.32A 4jsiA-4p2lA:
undetectable
4jsiB-4p2lA:
undetectable		 4jsiA-4p2lA:
21.63
4jsiB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 4k5dA-4p2lA:
undetectable
4k5dB-4p2lA:
undetectable		 4k5dA-4p2lA:
21.63
4k5dB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 4k5eA-4p2lA:
undetectable
4k5eB-4p2lA:
undetectable		 4k5eA-4p2lA:
21.63
4k5eB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.26A 4kchA-4p2lA:
undetectable
4kchB-4p2lA:
undetectable		 4kchA-4p2lA:
21.63
4kchB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.34A 4kckA-4p2lA:
undetectable
4kckB-4p2lA:
undetectable		 4kckA-4p2lA:
21.63
4kckB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4kclA-4p2lA:
undetectable
4kclB-4p2lA:
undetectable		 4kclA-4p2lA:
21.63
4kclB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 4kcmA-4p2lA:
undetectable
4kcmB-4p2lA:
undetectable		 4kcmA-4p2lA:
21.63
4kcmB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 8 SER A 472
SER A 474
HIS A 422
GLU A 426
 None
 1.13A 4ms4A-4p2lA:
undetectable		 4ms4A-4p2lA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.30A 4uh1A-4p2lA:
undetectable
4uh1B-4p2lA:
undetectable		 4uh1A-4p2lA:
21.63
4uh1B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4uh1A-4p2lA:
undetectable
4uh1B-4p2lA:
undetectable		 4uh1A-4p2lA:
21.63
4uh1B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.32A 4uh2A-4p2lA:
undetectable
4uh2B-4p2lA:
undetectable		 4uh2A-4p2lA:
21.63
4uh2B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 4uh5A-4p2lA:
undetectable
4uh5B-4p2lA:
undetectable		 4uh5A-4p2lA:
19.10
4uh5B-4p2lA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 4upnA-4p2lA:
undetectable
4upnB-4p2lA:
undetectable		 4upnA-4p2lA:
21.63
4upnB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 4upoA-4p2lA:
undetectable
4upoB-4p2lA:
undetectable		 4upoA-4p2lA:
21.63
4upoB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 4uppA-4p2lA:
undetectable
4uppB-4p2lA:
undetectable		 4uppA-4p2lA:
21.63
4uppB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.25A 4v3wA-4p2lA:
undetectable
4v3wB-4p2lA:
undetectable		 4v3wA-4p2lA:
21.63
4v3wB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 4v3yA-4p2lA:
undetectable
4v3yB-4p2lA:
undetectable		 4v3yA-4p2lA:
21.63
4v3yB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 8 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.27A 4v3yA-4p2lA:
undetectable
4v3yB-4p2lA:
undetectable		 4v3yA-4p2lA:
21.63
4v3yB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 5ad5A-4p2lA:
undetectable
5ad5B-4p2lA:
undetectable		 5ad5A-4p2lA:
21.63
5ad5B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 5ad5A-4p2lA:
undetectable
5ad5B-4p2lA:
undetectable		 5ad5A-4p2lA:
21.63
5ad5B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.27A 5ad6A-4p2lA:
undetectable
5ad6B-4p2lA:
undetectable		 5ad6A-4p2lA:
21.63
5ad6B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.36A 5ad9A-4p2lA:
undetectable
5ad9B-4p2lA:
undetectable		 5ad9A-4p2lA:
21.63
5ad9B-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.36A 5adbA-4p2lA:
undetectable
5adbB-4p2lA:
undetectable		 5adbA-4p2lA:
21.63
5adbB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 5adcA-4p2lA:
undetectable
5adcB-4p2lA:
undetectable		 5adcA-4p2lA:
21.63
5adcB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.27A 5addA-4p2lA:
undetectable
5addB-4p2lA:
undetectable		 5addA-4p2lA:
21.63
5addB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 5aglA-4p2lA:
undetectable
5aglB-4p2lA:
undetectable		 5aglA-4p2lA:
21.63
5aglB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.27A 5agmA-4p2lA:
undetectable
5agmB-4p2lA:
undetectable		 5agmA-4p2lA:
21.63
5agmB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 5fvqA-4p2lA:
undetectable
5fvqB-4p2lA:
undetectable		 5fvqA-4p2lA:
21.63
5fvqB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.27A 5fvrA-4p2lA:
undetectable
5fvrB-4p2lA:
undetectable		 5fvrA-4p2lA:
21.63
5fvrB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.24A 5fvsA-4p2lA:
undetectable
5fvsB-4p2lA:
undetectable		 5fvsA-4p2lA:
21.63
5fvsB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.27A 5fvtA-4p2lA:
undetectable
5fvtB-4p2lA:
undetectable		 5fvtA-4p2lA:
21.63
5fvtB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 6 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.25A 5fvuA-4p2lA:
undetectable
5fvuB-4p2lA:
undetectable		 5fvuA-4p2lA:
19.10
5fvuB-4p2lA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.28A 5fvwA-4p2lA:
undetectable
5fvwB-4p2lA:
undetectable		 5fvwA-4p2lA:
19.10
5fvwB-4p2lA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.29A 5fvxA-4p2lA:
undetectable
5fvxB-4p2lA:
undetectable		 5fvxA-4p2lA:
19.10
5fvxB-4p2lA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 5g0pA-4p2lA:
undetectable
5g0pB-4p2lA:
undetectable		 5g0pA-4p2lA:
21.63
5g0pB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 8 PHE A 195
ARG A 220
PRO A 173
ALA A 174
 None
 0.81A 5m0oC-4p2lA:
undetectable		 5m0oC-4p2lA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		5 / 12 ALA A 341
GLU A 383
LEU A 311
ILE A 314
PHE A 374
 None
 1.16A 5vlmE-4p2lA:
undetectable		 5vlmE-4p2lA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 5vuiA-4p2lA:
undetectable
5vuiB-4p2lA:
undetectable		 5vuiA-4p2lA:
21.63
5vuiB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.18A 5vujA-4p2lA:
undetectable
5vujB-4p2lA:
undetectable		 5vujA-4p2lA:
21.63
5vujB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 5vukA-4p2lA:
undetectable
5vukB-4p2lA:
undetectable		 5vukA-4p2lA:
21.63
5vukB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 5vumA-4p2lA:
undetectable
5vumB-4p2lA:
undetectable		 5vumA-4p2lA:
21.63
5vumB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 5vuqA-4p2lA:
undetectable
5vuqB-4p2lA:
undetectable		 5vuqA-4p2lA:
21.63
5vuqB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.30A 5vurA-4p2lA:
undetectable
5vurB-4p2lA:
undetectable		 5vurA-4p2lA:
21.63
5vurB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 5vutA-4p2lA:
undetectable
5vutB-4p2lA:
undetectable		 5vutA-4p2lA:
21.63
5vutB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.31A 5vuuA-4p2lA:
undetectable
5vuuB-4p2lA:
undetectable		 5vuuA-4p2lA:
21.63
5vuuB-4p2lA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.31A 5vuwA-4p2lA:
undetectable
5vuwB-4p2lA:
undetectable		 5vuwA-4p2lA:
19.10
5vuwB-4p2lA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 5 ASN A 246
VAL A 216
LEU A 266
SER A 250
 None
 1.02A 6a7pA-4p2lA:
2.0		 6a7pA-4p2lA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.28A 6ausA-4p2lA:
undetectable
6ausB-4p2lA:
undetectable		 6ausA-4p2lA:
8.89
6ausB-4p2lA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 PHE A  68
GLU A 115
ARG A 125
VAL A  53
 None
 1.29A 6av0A-4p2lA:
undetectable
6av0B-4p2lA:
undetectable		 6av0A-4p2lA:
8.50
6av0B-4p2lA:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.30A 6av3A-4p2lA:
undetectable
6av3B-4p2lA:
undetectable		 6av3A-4p2lA:
8.50
6av3B-4p2lA:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4p2l SULFHYDRYL OXIDASE 1
(Rattus
norvegicus) 		4 / 7 ARG A 125
VAL A  53
PHE A  68
GLU A 115
 None
 1.30A 6cicA-4p2lA:
undetectable
6cicB-4p2lA:
undetectable		 6cicA-4p2lA:
8.50
6cicB-4p2lA:
8.50