SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4p3y THIOL:DISULFIDE
INTERCHANGE PROTEIN
(Acinetobacter
baumannii) 		5 / 11 GLU B  28
ALA B  72
GLY B  71
TYR B  75
PHE B  57
 None
 1.30A 1l5rA-4p3yB:
2.1		 1l5rA-4p3yB:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 4p3y THIOL:DISULFIDE
INTERCHANGE PROTEIN
(Acinetobacter
baumannii) 		4 / 8 GLN B  96
PRO B  35
PRO B 151
GLU B  28
 None
 1.12A 3oyaA-4p3yB:
undetectable		 3oyaA-4p3yB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4p3y THIOL:DISULFIDE
INTERCHANGE PROTEIN
(Acinetobacter
baumannii) 		4 / 5 PHE B 112
TYR B  75
LYS B 121
ARG B  73
 None
 1.43A 3sufD-4p3yB:
0.0		 3sufD-4p3yB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4p3y THIOL:DISULFIDE
INTERCHANGE PROTEIN
(Acinetobacter
baumannii) 		3 / 3 TYR B  76
THR B  60
GLU B  69
 None
 0.70A 4df3A-4p3yB:
undetectable		 4df3A-4p3yB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4p3y THIOL:DISULFIDE
INTERCHANGE PROTEIN
(Acinetobacter
baumannii) 		3 / 3 TYR B  76
THR B  60
GLU B  69
 None
 0.73A 4df3B-4p3yB:
undetectable		 4df3B-4p3yB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4p3y THIOL:DISULFIDE
INTERCHANGE PROTEIN
(Acinetobacter
baumannii) 		4 / 5 VAL B  83
ARG B  86
GLY B 116
TYR B 115
 None
 1.39A 5x80A-4p3yB:
undetectable
5x80B-4p3yB:
undetectable		 5x80A-4p3yB:
19.69
5x80B-4p3yB:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4p3y THIOL:DISULFIDE
INTERCHANGE PROTEIN
(Acinetobacter
baumannii) 		4 / 5 GLY B 116
TYR B 115
VAL B  83
ARG B  86
 None
 1.37A 5x80C-4p3yB:
undetectable
5x80D-4p3yB:
undetectable		 5x80C-4p3yB:
19.69
5x80D-4p3yB:
19.69