SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 5 THR A 233
GLU A 212
THR A 174
LEU A 187
 None
 0.95A 1d4fC-4p47A:
undetectable		 1d4fC-4p47A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 1.01A 1fbyA-4p47A:
undetectable		 1fbyA-4p47A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 1.00A 1fbyB-4p47A:
undetectable		 1fbyB-4p47A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 1.03A 1fm6A-4p47A:
undetectable		 1fm6A-4p47A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 10 MET A 133
LEU A 136
LEU A  83
LEU A  80
LEU A 144
 None
 1.35A 1pcgB-4p47A:
undetectable		 1pcgB-4p47A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 10 ALA A 267
GLU A 266
LEU A  54
MET A  90
ILE A  32
 None
 1.35A 1qkuA-4p47A:
undetectable		 1qkuA-4p47A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 10 ALA A 267
GLU A 266
LEU A  54
MET A  90
ILE A  32
 None
 1.35A 1qkuB-4p47A:
undetectable		 1qkuB-4p47A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 10 ALA A 267
GLU A 266
LEU A  54
MET A  90
ILE A  32
 None
 1.35A 1qkuC-4p47A:
undetectable		 1qkuC-4p47A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 218
GLY A 210
VAL A 226
GLU A 225
ASN A 213
 None
 1.07A 1sg9C-4p47A:
undetectable		 1sg9C-4p47A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 0.96A 1xdkE-4p47A:
undetectable		 1xdkE-4p47A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 1.00A 1xiuA-4p47A:
undetectable		 1xiuA-4p47A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 5 PHE A  34
PHE A  51
TRP A 147
GLY A 143
 None
 1.43A 2qmzA-4p47A:
undetectable
2qmzB-4p47A:
2.4		 2qmzA-4p47A:
21.59
2qmzB-4p47A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 312
ILE A 172
ILE A 167
THR A 233
HIS A 235
 None
 1.10A 2qo5A-4p47A:
undetectable		 2qo5A-4p47A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 312
ILE A 172
THR A 233
PHE A 112
HIS A 235
 None
 1.01A 2qo5A-4p47A:
undetectable		 2qo5A-4p47A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 SER A  29
ARG A  28
GLN A  30
 None
 1.01A 2xnrA-4p47A:
undetectable		 2xnrA-4p47A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 SER A 177
GLU A 212
ASP A 109
 None
 0.72A 2zthA-4p47A:
undetectable		 2zthA-4p47A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 SER A 177
GLU A 212
ASP A 109
 None
 0.77A 3bwmA-4p47A:
undetectable		 3bwmA-4p47A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 SER A 177
GLU A 212
ASP A 109
 None
 0.70A 3bwyA-4p47A:
undetectable		 3bwyA-4p47A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ALA A 267
LEU A 144
VAL A 242
ILE A  32
PHE A  34
 None
 1.15A 3datA-4p47A:
undetectable		 3datA-4p47A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 7 LEU A 136
ARG A 135
GLY A  96
SER A  99
 None
 0.82A 4cp3A-4p47A:
undetectable
4cp3B-4p47A:
undetectable		 4cp3A-4p47A:
18.59
4cp3B-4p47A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 11 ILE A 244
ALA A 264
ALA A 263
ILE A  63
VAL A  65
 None
 1.02A 4h1nA-4p47A:
undetectable		 4h1nA-4p47A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 7 LEU A  54
VAL A  55
TYR A 270
GLU A 266
 None
 1.00A 4lb2A-4p47A:
undetectable		 4lb2A-4p47A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 0.89A 4nqaH-4p47A:
undetectable		 4nqaH-4p47A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 ASP A  76
ARG A 173
ARG A 152
 None
 0.98A 4x5iA-4p47A:
undetectable		 4x5iA-4p47A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 6 ILE A 312
PHE A 328
THR A 323
ARG A 335
 None
 1.18A 4xe5A-4p47A:
undetectable		 4xe5A-4p47A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 SER A 177
GLU A 212
ASP A 109
 None
 0.74A 4xudA-4p47A:
undetectable		 4xudA-4p47A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 10 MET A 133
LEU A 136
LEU A  83
LEU A  80
LEU A 144
 None
 1.32A 5dxeB-4p47A:
undetectable		 5dxeB-4p47A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 9 MET A 133
LEU A 136
LEU A  83
LEU A  80
LEU A 144
 None
 1.35A 5dxgA-4p47A:
undetectable		 5dxgA-4p47A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 ASP A  76
ARG A 173
ARG A 152
 None
 0.97A 5eajB-4p47A:
undetectable		 5eajB-4p47A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		3 / 3 TRP A 249
GLU A 261
ASP A 254
 None
 1.04A 5gqbA-4p47A:
undetectable		 5gqbA-4p47A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 VAL A  65
ALA A 263
VAL A  55
LEU A 252
ILE A 241
 None
 1.23A 5hv1A-4p47A:
undetectable		 5hv1A-4p47A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 10 MET A 133
LEU A 136
LEU A  83
LEU A  80
LEU A 144
 None
 1.35A 5hyrA-4p47A:
undetectable		 5hyrA-4p47A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 PHE A  34
ALA A  35
ALA A 107
ALA A 104
LEU A 136
 None
 1.27A 5tl8A-4p47A:
undetectable		 5tl8A-4p47A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 0.95A 5uanA-4p47A:
undetectable		 5uanA-4p47A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		4 / 8 ILE A 241
GLN A  84
VAL A 102
ASP A 109
 None
 1.02A 5vlmF-4p47A:
undetectable		 5vlmF-4p47A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 GLY A  82
VAL A  88
ALA A  35
PHE A  68
GLY A  74
 None
 0.76A 5xv7A-4p47A:
undetectable		 5xv7A-4p47A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 0.96A 5z12B-4p47A:
undetectable		 5z12B-4p47A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 0.99A 5z12C-4p47A:
undetectable		 5z12C-4p47A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4p47 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Ochrobactrum
anthropi) 		5 / 12 ILE A 260
ALA A 264
ALA A 263
LEU A 144
ALA A 145
 None
 0.97A 6a5yD-4p47A:
undetectable		 6a5yD-4p47A:
16.23