SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p5n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 4p5n HYPOTHETICAL PROTEIN
CNAG_02591
(Cryptococcus
neoformans) 		4 / 4 ASP A  75
ASP A  73
GLY A  31
THR A  22
 None
None
None
CD  A 101 (-2.8A)
 1.28A 3tl9B-4p5nA:
undetectable		 3tl9B-4p5nA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4p5n HYPOTHETICAL PROTEIN
CNAG_02591
(Cryptococcus
neoformans) 		4 / 6 HIS A  29
VAL A  64
LEU A  71
THR A  22
 None
None
None
CD  A 101 (-2.8A)
 1.17A 5ogjA-4p5nA:
undetectable		 5ogjA-4p5nA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4p5n HYPOTHETICAL PROTEIN
CNAG_02591
(Cryptococcus
neoformans) 		4 / 6 HIS A  29
VAL A  64
LEU A  71
THR A  22
 None
None
None
CD  A 101 (-2.8A)
 1.18A 5ogjB-4p5nA:
undetectable		 5ogjB-4p5nA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4p5n HYPOTHETICAL PROTEIN
CNAG_02591
(Cryptococcus
neoformans) 		4 / 5 HIS A  29
VAL A  64
LEU A  71
THR A  22
 None
None
None
CD  A 101 (-2.8A)
 1.17A 5ohhA-4p5nA:
undetectable		 5ohhA-4p5nA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4p5n HYPOTHETICAL PROTEIN
CNAG_02591
(Cryptococcus
neoformans) 		4 / 6 HIS A  29
VAL A  64
LEU A  71
THR A  22
 None
None
None
CD  A 101 (-2.8A)
 1.18A 5ohhB-4p5nA:
undetectable		 5ohhB-4p5nA:
18.86