SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 4p5t PROTEIN OF 3K
PEPTIDE
(FEAQKAKANKAVD),LINK
ER REGION -
GGGGSLVPRGSGGGG,H-2
CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A BETA
CHAIN,H-2 CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A BETA
CHAIN
(Mus
musculus) 		5 / 11 LEU D 116
LEU D 104
VAL D 171
GLY D 169
ARG D 168
 None
 1.19A 1y4lB-4p5tD:
undetectable		 1y4lB-4p5tD:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4p5t PROTEIN OF 3K
PEPTIDE
(FEAQKAKANKAVD),LINK
ER REGION -
GGGGSLVPRGSGGGG,H-2
CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A BETA
CHAIN,H-2 CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A BETA
CHAIN
(Mus
musculus) 		4 / 4 VAL D 141
THR D 140
GLU D 139
GLU D 138
 None
 1.35A 4l78A-4p5tD:
undetectable		 4l78A-4p5tD:
11.13