SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4p5x CALCIUM-BINDING
MITOCHONDRIAL
CARRIER PROTEIN
ARALAR1
(Homo
sapiens) 		4 / 6 TYR A 272
ASP A 276
THR A 285
GLU A 247
 None
 1.48A 2dttB-4p5xA:
undetectable
2dttC-4p5xA:
undetectable		 2dttB-4p5xA:
15.34
2dttC-4p5xA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 4p5x CALCIUM-BINDING
MITOCHONDRIAL
CARRIER PROTEIN
ARALAR1
(Homo
sapiens) 		5 / 12 TYR A 218
LEU A 277
ALA A 205
ASP A 276
LEU A 266
 None
 1.13A 2jn3A-4p5xA:
undetectable		 2jn3A-4p5xA:
19.51