SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 4p7a DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		5 / 12 GLU A 172
ILE A  25
ILE A 107
ALA A 111
MET A  35
 None
 1.15A 2gj5A-4p7aA:
undetectable		 2gj5A-4p7aA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4p7a DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		5 / 12 ILE A  32
ALA A  31
GLY A  55
LEU A 155
VAL A 194
 None
 1.01A 5i71A-4p7aA:
undetectable		 5i71A-4p7aA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4p7a DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		5 / 12 ILE A  32
ALA A  31
GLY A  55
LEU A 155
VAL A 194
 None
 0.98A 5i73A-4p7aA:
undetectable		 5i73A-4p7aA:
21.42