SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 ASP A 461
ILE A 192
ALA A 196
ILE A 221
THR A 188
 None
 1.48A 1aj6A-4p7hA:
undetectable		 1aj6A-4p7hA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 LEU A 614
TYR A 609
LEU A 390
GLY A 354
ALA A 355
 None
 1.07A 1cqeA-4p7hA:
2.1		 1cqeA-4p7hA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 ALA A 897
ILE A 801
LEU A 829
TYR A 879
THR A 895
 None
 1.24A 1ddrB-4p7hA:
undetectable		 1ddrB-4p7hA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 5 SER A  53
THR A  60
GLU A  55
GLY A  56
 None
 1.08A 1icrA-4p7hA:
undetectable
1icrB-4p7hA:
undetectable		 1icrA-4p7hA:
12.73
1icrB-4p7hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 5 GLU A  55
GLY A  56
SER A  53
THR A  60
 None
 1.08A 1icrA-4p7hA:
undetectable
1icrB-4p7hA:
undetectable		 1icrA-4p7hA:
12.73
1icrB-4p7hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 SER A  53
THR A  60
GLU A  55
GLY A  56
 None
 1.09A 1icuA-4p7hA:
undetectable
1icuB-4p7hA:
undetectable		 1icuA-4p7hA:
12.73
1icuB-4p7hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 GLU A  55
GLY A  56
SER A  53
THR A  60
 None
 1.10A 1icuA-4p7hA:
undetectable
1icuB-4p7hA:
undetectable		 1icuA-4p7hA:
12.73
1icuB-4p7hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 SER A  53
THR A  60
GLU A  55
GLY A  56
 None
 1.07A 1icuC-4p7hA:
undetectable
1icuD-4p7hA:
undetectable		 1icuC-4p7hA:
12.73
1icuD-4p7hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 5 SER A  53
THR A  60
GLU A  55
GLY A  56
 None
 1.10A 1icvC-4p7hA:
undetectable
1icvD-4p7hA:
undetectable		 1icvC-4p7hA:
12.73
1icvD-4p7hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 5 GLU A  55
GLY A  56
SER A  53
THR A  60
 None
 1.10A 1icvC-4p7hA:
undetectable
1icvD-4p7hA:
undetectable		 1icvC-4p7hA:
12.73
1icvD-4p7hA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 11 ALA A 897
ILE A 801
LEU A 829
TYR A 879
THR A 895
 None
 1.23A 1jomA-4p7hA:
undetectable		 1jomA-4p7hA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 SER A  53
THR A  60
GLU A  55
GLY A  56
 None
 1.11A 1kqbA-4p7hA:
undetectable
1kqbB-4p7hA:
undetectable		 1kqbA-4p7hA:
12.88
1kqbB-4p7hA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 5 GLU A  55
GLY A  56
SER A  53
THR A  60
 None
 1.12A 1kqbA-4p7hA:
undetectable
1kqbB-4p7hA:
undetectable		 1kqbA-4p7hA:
12.88
1kqbB-4p7hA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 SER A  53
THR A  60
GLU A  55
GLY A  56
 None
 1.08A 1kqbC-4p7hA:
undetectable
1kqbD-4p7hA:
undetectable		 1kqbC-4p7hA:
12.88
1kqbD-4p7hA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 GLU A  55
GLY A  56
SER A  53
THR A  60
 None
 1.08A 1kqbC-4p7hA:
undetectable
1kqbD-4p7hA:
undetectable		 1kqbC-4p7hA:
12.88
1kqbD-4p7hA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 PHE A 473
LEU A 534
MET A 539
 None
 0.77A 1mx1D-4p7hA:
undetectable		 1mx1D-4p7hA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 5 GLU A 775
LEU A 769
LEU A 772
LEU A 770
 None
 1.17A 1np1A-4p7hA:
undetectable		 1np1A-4p7hA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 PHE A 252
ILE A 220
ILE A 250
ILE A 174
ILE A 248
 None
 1.34A 1r5lA-4p7hA:
undetectable		 1r5lA-4p7hA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_B_MTXB170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 10 ALA A 897
ILE A 801
LEU A 829
TYR A 879
THR A 895
 None
 1.26A 1tdrB-4p7hA:
undetectable		 1tdrB-4p7hA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_B_MTXB170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 10 ALA A 897
ILE A 801
LEU A 831
TYR A 879
THR A 895
 None
 1.48A 1tdrB-4p7hA:
undetectable		 1tdrB-4p7hA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 ASP A 469
GLU A 677
ARG A 243
 None
 0.88A 1wopA-4p7hA:
undetectable		 1wopA-4p7hA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 ASP A 587
ASP A 469
ASN A 568
 None
 0.60A 2bm9D-4p7hA:
undetectable		 2bm9D-4p7hA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 11 ILE A 285
PHE A 436
TYR A 432
ARG A 272
GLY A 231
 None
 1.28A 2bxmA-4p7hA:
undetectable		 2bxmA-4p7hA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KI5_A_AC2A1_1
(PROTEIN (THYMIDINE
KINASE))		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 HIS A 691
GLU A 677
ILE A 674
ILE A 673
GLU A 179
 None
 1.42A 2ki5A-4p7hA:
undetectable		 2ki5A-4p7hA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.86A 2q5kA-4p7hA:
undetectable		 2q5kA-4p7hA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 11 ALA A 897
ILE A 801
LEU A 829
TYR A 879
THR A 895
 None
 1.34A 2zzaB-4p7hA:
undetectable		 2zzaB-4p7hA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 THR A 215
ALA A 223
GLU A 217
VAL A 459
ILE A 250
 None
 1.15A 3dl9A-4p7hA:
undetectable		 3dl9A-4p7hA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 10 ALA A 261
ASP A 262
GLY A 458
ILE A 457
ILE A 220
 None
 0.87A 3ekvA-4p7hA:
undetectable		 3ekvA-4p7hA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 ILE A 313
TYR A 283
ILE A 356
HIS A 358
 None
 0.98A 3eteA-4p7hA:
undetectable
3eteE-4p7hA:
undetectable		 3eteA-4p7hA:
19.14
3eteE-4p7hA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 5 ILE A 313
TYR A 283
ILE A 356
HIS A 358
 None
 0.96A 3eteB-4p7hA:
undetectable
3eteC-4p7hA:
undetectable		 3eteB-4p7hA:
19.14
3eteC-4p7hA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 7 ILE A 356
HIS A 358
ILE A 313
TYR A 283
 None
 0.98A 3eteD-4p7hA:
undetectable
3eteF-4p7hA:
undetectable		 3eteD-4p7hA:
19.14
3eteF-4p7hA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 11 ALA A 355
ASN A 391
LEU A 390
LEU A 617
VAL A 431
 None
 1.12A 3jw5A-4p7hA:
undetectable		 3jw5A-4p7hA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 TYR A 582
PHE A 465
GLY A 697
GLN A 475
GLY A 464
 None
 1.39A 3kmoA-4p7hA:
undetectable		 3kmoA-4p7hA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 LEU A 614
TYR A 609
LEU A 390
GLY A 354
ALA A 355
 None
 0.98A 3n8xB-4p7hA:
undetectable		 3n8xB-4p7hA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 PHE A 230
GLU A 328
PHE A 286
ALA A 331
ILE A 289
 None
 1.24A 3ndiA-4p7hA:
undetectable		 3ndiA-4p7hA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 11 LEU A 614
TYR A 609
LEU A 390
GLY A 354
ALA A 355
 None
 1.09A 3pghB-4p7hA:
undetectable		 3pghB-4p7hA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 LEU A 614
TYR A 609
LEU A 390
GLY A 354
ALA A 355
 None
 1.09A 3pghD-4p7hA:
undetectable		 3pghD-4p7hA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 8 HIS A 284
ILE A 285
ILE A 313
ARG A 281
 None
 1.07A 3sfeB-4p7hA:
undetectable
3sfeC-4p7hA:
undetectable		 3sfeB-4p7hA:
13.52
3sfeC-4p7hA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 PHE A 871
SER A 859
GLN A 856
 None
None
CRO  A 853 ( 2.9A)
 0.87A 3smtA-4p7hA:
undetectable		 3smtA-4p7hA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 PHE A 858
VAL A 899
ASN A 908
ILE A 801
PHE A 795
 None
None
CRO  A 853 ( 4.3A)
None
None
 1.17A 3t3rB-4p7hA:
undetectable		 3t3rB-4p7hA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 PHE A 858
VAL A 899
ASN A 908
ILE A 801
PHE A 795
 None
None
CRO  A 853 ( 4.3A)
None
None
 1.23A 3t3rC-4p7hA:
undetectable		 3t3rC-4p7hA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 10 PHE A 858
VAL A 899
ASN A 908
ILE A 801
PHE A 795
 None
None
CRO  A 853 ( 4.3A)
None
None
 1.18A 3t3rD-4p7hA:
undetectable		 3t3rD-4p7hA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 8 ASP A 522
ASN A 562
MET A 515
GLY A 514
 None
 0.97A 4fo4A-4p7hA:
undetectable		 4fo4A-4p7hA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 PRO A 675
TYR A 128
GLY A 682
 None
 0.58A 4g2zA-4p7hA:
undetectable		 4g2zA-4p7hA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 ILE A 939
MET A 865
ARG A 867
 None
 0.91A 4lnwA-4p7hA:
undetectable		 4lnwA-4p7hA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 ILE A 939
MET A 865
ARG A 867
 None
 0.89A 4lnxA-4p7hA:
undetectable		 4lnxA-4p7hA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 4 ILE A  51
VAL A  69
VAL A  59
ARG A  54
 None
 0.94A 4m6tA-4p7hA:
undetectable		 4m6tA-4p7hA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 VAL A 842
LEU A 840
LEU A 912
PHE A 952
 None
None
None
CRO  A 853 ( 4.6A)
 0.88A 4o1zA-4p7hA:
undetectable		 4o1zA-4p7hA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 ASP A 299
LYS A 294
LEU A 329
 None
 1.00A 4ptjA-4p7hA:
undetectable		 4ptjA-4p7hA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 11 ALA A 897
ILE A 801
LEU A 829
TYR A 879
THR A 895
 None
 1.28A 4qi9C-4p7hA:
undetectable		 4qi9C-4p7hA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 11 ALA A 897
ILE A 801
LEU A 829
TYR A 879
THR A 895
 None
 1.18A 4qlfA-4p7hA:
undetectable		 4qlfA-4p7hA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 ALA A 897
ILE A 801
LEU A 829
TYR A 879
THR A 895
 None
 1.18A 4qlgA-4p7hA:
undetectable		 4qlgA-4p7hA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 ALA A 897
ILE A 801
LEU A 829
TYR A 879
THR A 895
 None
 1.17A 4rgcA-4p7hA:
undetectable		 4rgcA-4p7hA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 7 LYS A 106
LEU A 105
ASN A 686
LEU A 693
 None
 0.72A 4wg0B-4p7hA:
undetectable
4wg0C-4p7hA:
undetectable		 4wg0B-4p7hA:
1.20
4wg0C-4p7hA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 7 ASN A 686
LEU A 693
LYS A 106
LEU A 105
 None
 0.69A 4wg0L-4p7hA:
undetectable
4wg0M-4p7hA:
undetectable		 4wg0L-4p7hA:
1.20
4wg0M-4p7hA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 7 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.78A 4zdzA-4p7hA:
undetectable		 4zdzA-4p7hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 PHE A 312
ILE A 356
GLY A 425
LEU A 399
LEU A 395
 None
 0.96A 4ze0A-4p7hA:
undetectable		 4ze0A-4p7hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 7 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.78A 4ze3A-4p7hA:
undetectable		 4ze3A-4p7hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 8 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.79A 5esjA-4p7hA:
undetectable		 5esjA-4p7hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 7 PHE A 312
ILE A 356
GLY A 425
LEU A 399
 None
 0.77A 5esmA-4p7hA:
undetectable		 5esmA-4p7hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 LEU A 614
TYR A 609
LEU A 390
GLY A 354
ALA A 355
 None
 1.04A 5ikrB-4p7hA:
undetectable		 5ikrB-4p7hA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 12 PRO A 876
LEU A 794
GLU A 902
PHE A 901
GLY A 903
 None
 1.36A 5il1A-4p7hA:
undetectable		 5il1A-4p7hA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 THR A 481
HIS A 651
ASN A 654
 None
 0.99A 5n4tA-4p7hA:
undetectable		 5n4tA-4p7hA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 VAL A 803
LYS A 900
MET A 875
 None
 0.86A 5nknA-4p7hA:
undetectable		 5nknA-4p7hA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 HIS A 492
HIS A 666
HIS A 668
 None
 0.97A 5oexA-4p7hA:
undetectable		 5oexA-4p7hA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 5 ASN A 391
VAL A 431
LEU A 352
SER A 613
 None
 1.30A 6a7pA-4p7hA:
undetectable		 6a7pA-4p7hA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 TYR A 609
ASN A 602
LEU A 427
 None
 0.83A 6b58A-4p7hA:
undetectable		 6b58A-4p7hA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 8 TYR A 109
THR A 678
TYR A 128
LEU A 688
 None
 1.20A 6cnjD-4p7hA:
2.7
6cnjE-4p7hA:
undetectable		 6cnjD-4p7hA:
5.46
6cnjE-4p7hA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 4 ARG A 243
GLU A 269
GLU A 280
ARG A 272
 None
 1.12A 6fk2A-4p7hA:
undetectable		 6fk2A-4p7hA:
9.82