SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p99'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A  56
GLY A  32
VAL A  83
ASP A  43
VAL A  45
 None
None
None
CA  A 510 ( 4.9A)
None
 1.21A 1akdA-4p99A:
undetectable		 1akdA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A 160
GLY A 136
VAL A 187
ASP A 147
VAL A 149
 None
None
None
CA  A 507 ( 4.9A)
None
 1.17A 1akdA-4p99A:
undetectable		 1akdA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A 264
GLY A 240
VAL A 291
ASP A 251
VAL A 253
 None
None
None
CA  A 520 ( 4.7A)
None
 1.19A 1akdA-4p99A:
undetectable		 1akdA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A 368
GLY A 344
VAL A 395
ASP A 355
VAL A 357
 None
 1.20A 1akdA-4p99A:
undetectable		 1akdA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		3 / 3 ALA A  12
VAL A  10
TRP A  64
 None
 0.61A 1micA-4p99A:
undetectable
1micB-4p99A:
undetectable		 1micA-4p99A:
3.53
1micB-4p99A:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		3 / 3 ALA A 116
VAL A 114
TRP A 168
 None
 0.62A 1micA-4p99A:
undetectable
1micB-4p99A:
undetectable		 1micA-4p99A:
3.53
1micB-4p99A:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		3 / 3 ALA A 220
VAL A 218
TRP A 272
 EDO  A 527 ( 4.7A)
None
None
 0.62A 1micA-4p99A:
undetectable
1micB-4p99A:
undetectable		 1micA-4p99A:
3.53
1micB-4p99A:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		3 / 3 ALA A 324
VAL A 322
TRP A 376
 EDO  A 528 (-3.9A)
None
None
 0.61A 1micA-4p99A:
undetectable
1micB-4p99A:
undetectable		 1micA-4p99A:
3.53
1micB-4p99A:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 5 ASP A  94
VAL A  93
SER A  85
ASP A  80
 None
None
None
CA  A 508 ( 2.3A)
 1.37A 1n2xB-4p99A:
undetectable		 1n2xB-4p99A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 5 ASP A 198
VAL A 197
SER A 189
ASP A 184
 None
 1.42A 1n2xB-4p99A:
undetectable		 1n2xB-4p99A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 5 ASP A 302
VAL A 301
SER A 293
ASP A 288
 None
EDO  A 530 (-4.8A)
None
CA  A 524 ( 2.2A)
 1.38A 1n2xB-4p99A:
undetectable		 1n2xB-4p99A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 5 ASP A 406
VAL A 405
SER A 397
ASP A 392
 None
 1.41A 1n2xB-4p99A:
undetectable		 1n2xB-4p99A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A  56
GLY A  32
VAL A  83
ASP A  43
VAL A  45
 None
None
None
CA  A 510 ( 4.9A)
None
 1.18A 1phgA-4p99A:
undetectable		 1phgA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A 160
GLY A 136
VAL A 187
ASP A 147
VAL A 149
 None
None
None
CA  A 507 ( 4.9A)
None
 1.14A 1phgA-4p99A:
undetectable		 1phgA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A 264
GLY A 240
VAL A 291
ASP A 251
VAL A 253
 None
None
None
CA  A 520 ( 4.7A)
None
 1.17A 1phgA-4p99A:
undetectable		 1phgA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A 368
GLY A 344
VAL A 395
ASP A 355
VAL A 357
 None
 1.17A 1phgA-4p99A:
undetectable		 1phgA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 4 THR A  14
GLY A 194
ASP A 191
ALA A  21
 CA  A 512 (-3.1A)
None
CA  A 515 (-3.5A)
None
 1.04A 1sg9A-4p99A:
undetectable		 1sg9A-4p99A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 4 THR A 118
GLY A 298
ASP A 295
ALA A 125
 CA  A 517 (-3.0A)
None
CA  A 519 (-3.3A)
None
 1.05A 1sg9A-4p99A:
undetectable		 1sg9A-4p99A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 4 THR A 222
GLY A 402
ASP A 399
ALA A 229
 CA  A 503 (-3.0A)
None
CA  A 501 (-3.4A)
None
 0.99A 1sg9A-4p99A:
undetectable		 1sg9A-4p99A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 12 GLU A 364
GLY A 363
ASP A 392
ASN A 362
ALA A 390
 None
None
None
None
CA  A 505 (-4.7A)
 1.08A 2bm9B-4p99A:
undetectable		 2bm9B-4p99A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 12 GLY A  97
ALA A  81
VAL A  30
VAL A  58
VAL A  45
 None
 0.98A 3ucbB-4p99A:
undetectable		 3ucbB-4p99A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 12 GLY A 305
ALA A 289
VAL A 238
VAL A 266
VAL A 253
 None
 1.00A 3ucbB-4p99A:
undetectable		 3ucbB-4p99A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A  56
GLY A  32
VAL A  83
ASP A  43
VAL A  45
 None
None
None
CA  A 510 ( 4.9A)
None
 1.14A 4c9nB-4p99A:
undetectable		 4c9nB-4p99A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A 160
GLY A 136
VAL A 187
ASP A 147
VAL A 149
 None
None
None
CA  A 507 ( 4.9A)
None
 1.11A 4c9nB-4p99A:
undetectable		 4c9nB-4p99A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A 264
GLY A 240
VAL A 291
ASP A 251
VAL A 253
 None
None
None
CA  A 520 ( 4.7A)
None
 1.12A 4c9nB-4p99A:
undetectable		 4c9nB-4p99A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A 368
GLY A 344
VAL A 395
ASP A 355
VAL A 357
 None
 1.13A 4c9nB-4p99A:
undetectable		 4c9nB-4p99A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 12 THR A 160
GLY A 136
VAL A 187
ASP A 147
VAL A 149
 None
None
None
CA  A 507 ( 4.9A)
None
 1.07A 4c9oA-4p99A:
undetectable		 4c9oA-4p99A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 12 THR A 160
GLY A 136
VAL A 187
ASP A 147
VAL A 149
 None
None
None
CA  A 507 ( 4.9A)
None
 1.06A 4c9oB-4p99A:
undetectable		 4c9oB-4p99A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A  56
GLY A  32
VAL A  83
ASP A  43
VAL A  45
 None
None
None
CA  A 510 ( 4.9A)
None
 1.21A 4c9pB-4p99A:
undetectable		 4c9pB-4p99A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A 160
GLY A 136
VAL A 187
ASP A 147
VAL A 149
 None
None
None
CA  A 507 ( 4.9A)
None
 1.18A 4c9pB-4p99A:
undetectable		 4c9pB-4p99A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A 264
GLY A 240
VAL A 291
ASP A 251
VAL A 253
 None
None
None
CA  A 520 ( 4.7A)
None
 1.19A 4c9pB-4p99A:
undetectable		 4c9pB-4p99A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A 368
GLY A 344
VAL A 395
ASP A 355
VAL A 357
 None
 1.20A 4c9pB-4p99A:
undetectable		 4c9pB-4p99A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 7 THR A  56
VAL A  83
ASP A  43
VAL A  45
 None
None
CA  A 510 ( 4.9A)
None
 0.90A 4cp4A-4p99A:
undetectable		 4cp4A-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 7 THR A 160
VAL A 187
ASP A 147
VAL A 149
 None
None
CA  A 507 ( 4.9A)
None
 0.88A 4cp4A-4p99A:
undetectable		 4cp4A-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 7 THR A 264
VAL A 291
ASP A 251
VAL A 253
 None
None
CA  A 520 ( 4.7A)
None
 0.91A 4cp4A-4p99A:
undetectable		 4cp4A-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 7 THR A 368
VAL A 395
ASP A 355
VAL A 357
 None
 0.92A 4cp4A-4p99A:
undetectable		 4cp4A-4p99A:
21.01