SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_B_ADNB502_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE
(Alcaligenes
sp.) 		4 / 5 ASP A  63
TRP A  61
PHE A 128
VAL A  82
 GOL  A 403 (-3.1A)
GOL  A 403 (-4.4A)
None
None
 1.19A 2zbuB-4p9gA:
0.0		 2zbuB-4p9gA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE
(Alcaligenes
sp.) 		5 / 10 HIS A 114
HIS A  76
HIS A  78
VAL A  82
VAL A  73
 FE  A 401 ( 3.2A)
FE  A 401 ( 3.1A)
FE  A 401 ( 3.1A)
None
None
 1.45A 3czvB-4p9gA:
undetectable		 3czvB-4p9gA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE
(Alcaligenes
sp.) 		3 / 3 LEU A  65
TRP A  91
GLY A  92
 None
 0.79A 3l35B-4p9gA:
undetectable
3l35K-4p9gA:
undetectable		 3l35B-4p9gA:
18.97
3l35K-4p9gA:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE
(Alcaligenes
sp.) 		4 / 5 VAL A 171
LEU A 174
ILE A  54
VAL A  41
 None
 0.96A 4a9kB-4p9gA:
undetectable		 4a9kB-4p9gA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE
(Alcaligenes
sp.) 		5 / 12 PRO A  79
SER A 144
GLY A 146
ASP A 152
ASP A 149
 None
 1.26A 5eeiA-4p9gA:
undetectable		 5eeiA-4p9gA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE
(Alcaligenes
sp.) 		5 / 12 PRO A  79
SER A 144
GLY A 146
ASP A 152
ASP A 149
 None
 1.25A 5eeiB-4p9gA:
undetectable		 5eeiB-4p9gA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE
(Alcaligenes
sp.) 		5 / 12 MET A 156
TYR A 153
SER A  49
VAL A  41
PHE A 148
 None
GOL  A 403 (-4.1A)
GOL  A 403 (-3.5A)
None
GOL  A 403 ( 4.8A)
 1.41A 5g6sB-4p9gA:
undetectable
5g6sC-4p9gA:
undetectable		 5g6sB-4p9gA:
22.67
5g6sC-4p9gA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 4p9g 2,4'-DIHYDROXYACETOP
HENONE DIOXYGENASE
(Alcaligenes
sp.) 		3 / 3 HIS A  76
HIS A 114
HIS A  78
 FE  A 401 ( 3.1A)
FE  A 401 ( 3.2A)
FE  A 401 ( 3.1A)
 0.36A 5zrdA-4p9gA:
undetectable		 5zrdA-4p9gA:
16.37