SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4p9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 4p9j RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 TYR C1122
GLY C1103
SER C1193
ALA C1077
ILE C1153
 None
 1.13A 1ve3A-4p9jC:
undetectable		 1ve3A-4p9jC:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 4p9j RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 TYR C1122
GLY C1103
SER C1193
ALA C1077
ILE C1153
 None
 1.15A 1ve3B-4p9jC:
undetectable		 1ve3B-4p9jC:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 4p9j RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 LEU C1211
LEU C1204
CYH C1151
THR C1163
 None
 1.20A 2oaxD-4p9jC:
undetectable		 2oaxD-4p9jC:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4p9j RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 ARG C1110
HIS C1133
ALA C1121
GLU C1119
 None
 1.32A 5a06C-4p9jC:
undetectable
5a06D-4p9jC:
undetectable		 5a06C-4p9jC:
18.42
5a06D-4p9jC:
18.42