SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 4pau NITROGEN REGULATORY
PROTEIN A
(Staphylococcus
aureus) 		3 / 3 VAL A 116
VAL A 119
TRP A 111
 None
 0.88A 1av2C-4pauA:
undetectable
1av2D-4pauA:
undetectable		 1av2C-4pauA:
15.94
1av2D-4pauA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 4pau NITROGEN REGULATORY
PROTEIN A
(Staphylococcus
aureus) 		3 / 3 ARG A 125
ASP A  17
GLN A  13
 None
 0.82A 4azsA-4pauA:
undetectable		 4azsA-4pauA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 4pau NITROGEN REGULATORY
PROTEIN A
(Staphylococcus
aureus) 		3 / 3 ARG A 125
ARG A 128
ASP A  26
 None
 0.97A 6d8pA-4pauA:
undetectable		 6d8pA-4pauA:
12.87