SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pav'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		4 / 5 PHE A 120
LEU A  50
VAL A  48
VAL A  71
 None
 1.13A 1t88B-4pavA:
undetectable		 1t88B-4pavA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ALA A  18
LEU A  50
PHE A  26
ILE A  73
LEU A  75
 None
 1.02A 2w3mA-4pavA:
undetectable		 2w3mA-4pavA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A 120
LEU A  50
VAL A  48
VAL A  71
 None
 1.10A 2zuhA-4pavA:
undetectable		 2zuhA-4pavA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		3 / 3 SER A  17
GLU A  52
ASP A 116
 None
 0.87A 3bwmA-4pavA:
undetectable		 3bwmA-4pavA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		3 / 3 SER A  17
GLU A  52
ASP A 116
 None
 0.86A 3bwyA-4pavA:
undetectable		 3bwyA-4pavA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A 120
LEU A  50
VAL A  48
VAL A  71
 None
 1.08A 4ek1A-4pavA:
undetectable		 4ek1A-4pavA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A 120
LEU A  50
VAL A  48
VAL A  71
 None
 1.09A 4g3rA-4pavA:
undetectable		 4g3rA-4pavA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ALA A  18
LEU A  50
PHE A  26
ILE A  73
LEU A  75
 None
 1.01A 4kebB-4pavA:
undetectable		 4kebB-4pavA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFJ_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ALA A  18
LEU A  50
PHE A  26
ILE A  73
LEU A  75
 None
 1.00A 4kfjB-4pavA:
undetectable		 4kfjB-4pavA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A 120
LEU A  50
VAL A  48
VAL A  71
 None
 1.13A 4kkyX-4pavA:
undetectable		 4kkyX-4pavA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A 120
LEU A  50
VAL A  48
VAL A  71
 None
 1.09A 4l4cA-4pavA:
undetectable		 4l4cA-4pavA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		4 / 5 SER A  17
GLU A  52
LYS A  54
ASP A 116
 None
 1.48A 4pclA-4pavA:
1.8		 4pclA-4pavA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		3 / 3 SER A  17
GLU A  52
ASP A 116
 None
 0.83A 4xudA-4pavA:
undetectable		 4xudA-4pavA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 4pav GLYOXALASE FAMILY
PROTEIN
(Staphylococcus
aureus) 		4 / 7 SER A  17
ILE A  51
GLU A  52
ASP A 116
 None
 0.92A 5n5dA-4pavA:
undetectable		 5n5dA-4pavA:
18.53