SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4pb6 VP1
(Feline
calicivirus) 		4 / 6 ALA A 300
SER A 305
ASN A 297
ILE A 296
 None
 1.02A 1yc2A-4pb6A:
undetectable		 1yc2A-4pb6A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4pb6 VP1
(Feline
calicivirus) 		4 / 5 SER A 384
GLY A 419
ASP A 581
ASP A 422
 None
 1.10A 2oxtB-4pb6A:
undetectable		 2oxtB-4pb6A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 4pb6 VP1
(Feline
calicivirus) 		5 / 11 VAL A 264
PRO A 263
TYR A 251
ILE A 234
ILE A 268
 None
 1.45A 3ganA-4pb6A:
undetectable		 3ganA-4pb6A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 4pb6 VP1
(Feline
calicivirus) 		3 / 3 ASP A 626
SER A 625
ARG A 559
 None
 0.96A 3loqA-4pb6A:
undetectable		 3loqA-4pb6A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 4pb6 VP1
(Feline
calicivirus) 		3 / 3 TYR A 451
MET A 466
LEU A 429
 None
 1.00A 3vw1D-4pb6A:
undetectable		 3vw1D-4pb6A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 LEU A 201
LEU A 204
MET A 279
ILE A 215
LEU A 196
 None
 1.19A 4j24B-4pb6A:
undetectable		 4j24B-4pb6A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 ASP A 241
VAL A 235
ILE A 234
LEU A 652
ILE A 187
 None
 1.12A 5b8iC-4pb6A:
undetectable		 5b8iC-4pb6A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 VAL A 254
PHE A 256
ILE A 289
LEU A 652
ALA A 192
 None
 1.50A 5fctB-4pb6A:
undetectable		 5fctB-4pb6A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 LEU A 657
GLY A 622
ASP A 624
GLN A 651
LEU A 652
 None
 1.07A 5hg0A-4pb6A:
undetectable		 5hg0A-4pb6A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 ILE A 623
PHE A 606
THR A 556
VAL A 367
LEU A 601
 None
 1.04A 5nz0A-4pb6A:
undetectable		 5nz0A-4pb6A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 4pb6 VP1
(Feline
calicivirus) 		3 / 3 TYR A 599
ALA A 607
LEU A 341
 None
 0.75A 6d9kF-4pb6A:
undetectable		 6d9kF-4pb6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 VAL A 367
GLU A 555
LEU A 588
LEU A 594
ARG A 372
 None
 1.10A 6ew0B-4pb6A:
undetectable		 6ew0B-4pb6A:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 VAL A 367
GLU A 555
LEU A 588
LEU A 594
ARG A 372
 None
 1.10A 6ew0D-4pb6A:
undetectable		 6ew0D-4pb6A:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 VAL A 367
GLU A 555
LEU A 588
LEU A 594
ARG A 372
 None
 1.09A 6ew0H-4pb6A:
undetectable		 6ew0H-4pb6A:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 VAL A 367
GLU A 555
LEU A 588
LEU A 594
ARG A 372
 None
 1.09A 6ew0I-4pb6A:
undetectable		 6ew0I-4pb6A:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 4pb6 VP1
(Feline
calicivirus) 		5 / 12 PHE A 361
ILE A 621
LEU A 601
ASP A 624
ALA A 653
 None
 1.25A 6r2eH-4pb6A:
undetectable		 6r2eH-4pb6A:
20.00