SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pb9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 4pb9 AB64 HEAVY CHAIN
(Mus
musculus) 		4 / 8 ARG H  13
ASN H  82
HIS H  81
SER H  17
 None
 1.30A 1u1jA-4pb9H:
undetectable		 1u1jA-4pb9H:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 4pb9 AB64 HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER H 161
SER H 160
HIS H 164
 None
 0.83A 3mzeA-4pb9H:
undetectable		 3mzeA-4pb9H:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4pb9 AB64 HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL H 163
VAL H 181
SER H 179
ASN H 196
ASN H 155
 None
 1.43A 3nyaA-4pb9H:
undetectable		 3nyaA-4pb9H:
17.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 4pb9 AB64 HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.43A 4m7kH-4pb9H:
26.8		 4m7kH-4pb9H:
64.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4pb9 AB64 HEAVY CHAIN
(Mus
musculus) 		4 / 6 LEU H  11
ASP H 173
GLU H 148
ALA H 118
 None
 0.93A 4nkxA-4pb9H:
undetectable		 4nkxA-4pb9H:
17.62