SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pc4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		3 / 3 TRP A 186
TYR A 156
LEU A 107
 None
 0.88A 1kxhA-4pc4A:
undetectable		 1kxhA-4pc4A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		5 / 11 ASN A  52
VAL A  49
TYR A  64
ALA A  30
SER A  21
 MES  A 302 (-3.3A)
None
None
None
None
 1.47A 2iyfA-4pc4A:
undetectable		 2iyfA-4pc4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 5 GLU A 230
GLY A 229
TYR A 238
GLU A 211
 None
 1.00A 3w9tA-4pc4A:
14.3		 3w9tA-4pc4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 6 GLU A 230
GLY A 229
TYR A 238
GLU A 211
 None
 1.01A 3w9tB-4pc4A:
14.8		 3w9tB-4pc4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 5 GLU A 230
GLY A 229
TYR A 238
GLU A 211
 None
 1.01A 3w9tC-4pc4A:
14.3		 3w9tC-4pc4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 5 GLU A 230
GLY A 229
TYR A 238
GLU A 211
 None
 1.01A 3w9tD-4pc4A:
undetectable		 3w9tD-4pc4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 6 GLU A 230
GLY A 229
TYR A 238
GLU A 211
 None
 1.00A 3w9tE-4pc4A:
14.4		 3w9tE-4pc4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 6 GLU A 230
GLY A 229
TYR A 238
GLU A 211
 None
 1.01A 3w9tF-4pc4A:
14.5		 3w9tF-4pc4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 5 GLU A 230
GLY A 229
TYR A 238
GLU A 211
 None
 1.01A 3w9tG-4pc4A:
undetectable		 3w9tG-4pc4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		3 / 3 ASN A  60
GLU A  63
ARG A 143
 None
 0.81A 3wxoA-4pc4A:
undetectable		 3wxoA-4pc4A:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		5 / 11 ASN A  52
VAL A  49
TYR A  64
ALA A  30
SER A  21
 MES  A 302 (-3.3A)
None
None
None
None
 1.47A 4m83A-4pc4A:
undetectable		 4m83A-4pc4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		5 / 11 ASN A  52
VAL A  49
TYR A  64
ALA A  30
SER A  21
 MES  A 302 (-3.3A)
None
None
None
None
 1.47A 4m83B-4pc4A:
undetectable		 4m83B-4pc4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		3 / 3 MET A  62
GLN A  47
TYR A  80
 None
 1.05A 4udcA-4pc4A:
undetectable		 4udcA-4pc4A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 6 ASP A 122
GLY A 121
ASP A 221
LYS A 126
 None
 1.34A 5hp1C-4pc4A:
undetectable		 5hp1C-4pc4A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 4pc4 30K LIPOPROTEIN
(Bombyx
mori) 		4 / 5 TYR A  80
LYS A  79
GLY A  41
SER A  44
 None
None
None
MES  A 302 ( 4.9A)
 1.45A 5jhdJ-4pc4A:
undetectable		 5jhdJ-4pc4A:
23.25