SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pcb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFM_A_TOPA1290_1
(PTERIDINE REDUCTASE
1)		 4pcb TRWC
(Escherichia
coli) 		5 / 9 ASP A 111
LEU A 160
LEU A 200
LEU A 204
TYR A 196
 None
 1.23A 2bfmA-4pcbA:
undetectable
2bfmD-4pcbA:
undetectable		 2bfmA-4pcbA:
24.29
2bfmD-4pcbA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4pcb TRWC
(Escherichia
coli) 		4 / 8 GLY A  13
ARG A  14
LEU A   7
PHE A 148
 None
 0.83A 2vctC-4pcbA:
undetectable		 2vctC-4pcbA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4pcb TRWC
(Escherichia
coli) 		4 / 5 GLN A 126
THR A 189
HIS A   4
LEU A  84
 None
 1.37A 3ce6A-4pcbA:
undetectable		 3ce6A-4pcbA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 4pcb TRWC
(Escherichia
coli) 		4 / 6 ILE A 166
LEU A 118
PHE A  88
GLY A 193
 None
 0.94A 3sj1X-4pcbA:
undetectable		 3sj1X-4pcbA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4pcb TRWC
(Escherichia
coli) 		4 / 5 GLN A 126
THR A 189
HIS A   4
LEU A  84
 None
 1.31A 4lvcA-4pcbA:
undetectable		 4lvcA-4pcbA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4pcb TRWC
(Escherichia
coli) 		4 / 5 GLN A 126
THR A 189
HIS A   4
LEU A  84
 None
 1.32A 4lvcC-4pcbA:
undetectable		 4lvcC-4pcbA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4pcb TRWC
(Escherichia
coli) 		3 / 3 ARG A 112
HIS A 202
ARG A 116
 None
 0.96A 5iaoC-4pcbA:
undetectable		 5iaoC-4pcbA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4pcb TRWC
(Escherichia
coli) 		3 / 3 ARG A 112
HIS A 202
ARG A 116
 None
 0.95A 5iaoF-4pcbA:
undetectable		 5iaoF-4pcbA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 4pcb TRWC
(Escherichia
coli) 		4 / 5 GLN A 126
THR A 189
HIS A   4
LEU A  84
 None
 1.32A 6gbnA-4pcbA:
undetectable		 6gbnA-4pcbA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 4pcb TRWC
(Escherichia
coli) 		4 / 5 GLN A 126
THR A 189
HIS A   4
LEU A  84
 None
 1.30A 6gbnD-4pcbA:
undetectable		 6gbnD-4pcbA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 4pcb TRWC
(Escherichia
coli) 		4 / 8 HIS A 163
LEU A  84
GLY A  83
LEU A   7
 PO4  A 301 (-3.7A)
None
None
None
 0.79A 6mdqA-4pcbA:
undetectable		 6mdqA-4pcbA:
15.44