SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pcq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_A_NOVA400_2 (DNA GYRASE SUBUNIT B)	4pcq	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP/ASNC-FAMILY) (Mycobacterium tuberculosis)	3 / 3	ASN A 51 PHE A 81 VAL A 69	None	0.70A	1kijA-4pcqA: undetectable	1kijA-4pcqA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IG5_A_MMZA616_1 (LACTOPEROXIDASE)	4pcq	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP/ASNC-FAMILY) (Mycobacterium tuberculosis)	4 / 5	GLN A 95 HIS A 138 GLU A 171 LEU A 168	None	1.43A	4ig5A-4pcqA: undetectable	4ig5A-4pcqA: 14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IG5_B_MMZB617_1 (LACTOPEROXIDASE)	4pcq	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP/ASNC-FAMILY) (Mycobacterium tuberculosis)	4 / 5	GLN A 95 HIS A 138 GLU A 171 LEU A 168	None	1.48A	4ig5B-4pcqA: undetectable	4ig5B-4pcqA: 14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PTH_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	4pcq	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP/ASNC-FAMILY) (Mycobacterium tuberculosis)	3 / 3	ASP A 146 LEU A 147 PHE A 150	None	0.68A	4pthA-4pcqA: undetectable	4pthA-4pcqA: 24.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KIJ_A_NOVA400_2","DNA GYRASE SUBUNIT B","4pcq","POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP\/ASNC-FAMILY)","Mycobacterium tuberculosis",3,"ASN A  51;PHE A  81;VAL A  69","None","0.70A","1kijA-4pcqA:undetectable","1kijA-4pcqA:20.77"],["4IG5_A_MMZA616_1","LACTOPEROXIDASE","4pcq","POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP\/ASNC-FAMILY)","Mycobacterium tuberculosis",4,"GLN A  95;HIS A 138;GLU A 171;LEU A 168","None","1.43A","4ig5A-4pcqA:undetectable","4ig5A-4pcqA:14.72"],["4IG5_B_MMZB617_1","LACTOPEROXIDASE","4pcq","POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP\/ASNC-FAMILY)","Mycobacterium tuberculosis",4,"GLN A  95;HIS A 138;GLU A 171;LEU A 168","None","1.48A","4ig5B-4pcqA:undetectable","4ig5B-4pcqA:14.72"],["4PTH_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","4pcq","POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP\/ASNC-FAMILY)","Mycobacterium tuberculosis",3,"ASP A 146;LEU A 147;PHE A 150","None","0.68A","4pthA-4pcqA:undetectable","4pthA-4pcqA:24.17"]]