SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pdx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 8 MET A 212
PRO A 264
ASP A 543
ARG A 546
 None
 1.24A 1dtlA-4pdxA:
undetectable		 1dtlA-4pdxA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 5 ALA A  33
ALA A 524
LYS A 525
GLU A 529
 None
 1.02A 1e7cA-4pdxA:
undetectable		 1e7cA-4pdxA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 VAL A 152
ASP A 132
ALA A 309
HIS A 317
TYR A 234
 None
None
None
SO4  A 701 (-4.3A)
None
 1.08A 1kiaB-4pdxA:
undetectable		 1kiaB-4pdxA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 VAL A 152
ASP A 132
ALA A 309
HIS A 317
TYR A 234
 None
None
None
SO4  A 701 (-4.3A)
None
 1.09A 1kiaC-4pdxA:
undetectable		 1kiaC-4pdxA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 VAL A 152
ASP A 132
ALA A 309
HIS A 317
TYR A 234
 None
None
None
SO4  A 701 (-4.3A)
None
 1.08A 1kiaD-4pdxA:
undetectable		 1kiaD-4pdxA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 VAL A 152
ASP A 132
ALA A 309
HIS A 317
TYR A 234
 None
None
None
SO4  A 701 (-4.3A)
None
 1.08A 1nbhC-4pdxA:
undetectable		 1nbhC-4pdxA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		3 / 3 ILE A 276
ASP A 283
PHE A 284
 None
 0.59A 1uwjB-4pdxA:
undetectable		 1uwjB-4pdxA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 7 LEU A 617
PHE A 554
LEU A 641
MET A 577
 None
 0.90A 1wrlE-4pdxA:
undetectable
1wrlF-4pdxA:
undetectable		 1wrlE-4pdxA:
9.82
1wrlF-4pdxA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		3 / 3 TRP A 410
ARG A  56
PHE A  59
 None
 1.40A 1zeaH-4pdxA:
undetectable
1zeaL-4pdxA:
undetectable		 1zeaH-4pdxA:
17.76
1zeaL-4pdxA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 8 TYR A 416
GLY A 518
THR A 515
ALA A 514
 SO4  A 701 (-4.5A)
None
None
None
 0.80A 2a1hA-4pdxA:
undetectable
2a1hB-4pdxA:
undetectable		 2a1hA-4pdxA:
18.25
2a1hB-4pdxA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 5 LEU A 161
ASP A 162
PRO A 154
ALA A 157
 None
 1.03A 2aofB-4pdxA:
undetectable		 2aofB-4pdxA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 10 TYR A 232
THR A 522
THR A 659
VAL A 531
GLY A 530
 None
 1.40A 2cp4A-4pdxA:
undetectable		 2cp4A-4pdxA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		3 / 3 ASN A 135
ARG A 129
ASP A  58
 None
 0.98A 2qe6A-4pdxA:
undetectable		 2qe6A-4pdxA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 6 PHE A  92
TRP A 107
GLY A 249
GLY A 251
 None
 0.92A 2qr2A-4pdxA:
undetectable
2qr2B-4pdxA:
undetectable		 2qr2A-4pdxA:
16.41
2qr2B-4pdxA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 5 TRP A 107
GLY A 249
GLY A 251
PHE A  92
 None
 0.92A 2qr2A-4pdxA:
undetectable
2qr2B-4pdxA:
undetectable		 2qr2A-4pdxA:
16.41
2qr2B-4pdxA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 8 ILE A 396
ASN A 394
ARG A 477
SER A 420
 None
 1.13A 2zw9B-4pdxA:
undetectable		 2zw9B-4pdxA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 7 PHE A  92
GLY A 247
ASP A  89
ARG A  86
 None
 1.27A 3aruA-4pdxA:
undetectable		 3aruA-4pdxA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 10 ILE A 133
GLY A 251
HIS A 355
TYR A 416
HIS A 317
 None
None
None
SO4  A 701 (-4.5A)
SO4  A 701 (-4.3A)
 1.16A 3boyA-4pdxA:
undetectable
3boyC-4pdxA:
undetectable		 3boyA-4pdxA:
12.95
3boyC-4pdxA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 10 TYR A 416
HIS A 317
ILE A 133
GLY A 251
HIS A 355
 SO4  A 701 (-4.5A)
SO4  A 701 (-4.3A)
None
None
None
 1.16A 3boyA-4pdxA:
undetectable
3boyB-4pdxA:
undetectable		 3boyA-4pdxA:
12.95
3boyB-4pdxA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA3001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 10 TYR A 416
HIS A 317
ILE A 133
GLY A 251
HIS A 355
 SO4  A 701 (-4.5A)
SO4  A 701 (-4.3A)
None
None
None
 1.16A 3boyB-4pdxA:
undetectable
3boyC-4pdxA:
undetectable		 3boyB-4pdxA:
12.95
3boyC-4pdxA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_D_TMQD614_1
(DHFR-TS)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 10 VAL A 174
ILE A 276
ILE A 300
PRO A 301
ILE A 146
 None
 1.15A 3clbD-4pdxA:
undetectable		 3clbD-4pdxA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		3 / 3 TYR A 234
ASP A 132
HIS A 182
 None
None
SO4  A 701 (-4.0A)
 0.91A 3e23A-4pdxA:
undetectable		 3e23A-4pdxA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 8 ILE A 192
TYR A 178
HIS A 185
GLY A 187
 None
 0.86A 3em0B-4pdxA:
undetectable		 3em0B-4pdxA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 10 VAL A 174
ILE A 276
ILE A 300
PRO A 301
ILE A 146
 None
 1.17A 3hbbD-4pdxA:
undetectable		 3hbbD-4pdxA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 5 ILE A 177
PHE A 298
ASP A 283
GLU A 281
 None
 1.13A 3kp6A-4pdxA:
undetectable
3kp6B-4pdxA:
undetectable		 3kp6A-4pdxA:
12.80
3kp6B-4pdxA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 7 LEU A  76
ASP A 132
THR A 153
ALA A 156
 None
 1.08A 3mbgA-4pdxA:
undetectable
3mbgB-4pdxA:
undetectable		 3mbgA-4pdxA:
11.29
3mbgB-4pdxA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 11 GLN A 127
ASP A 149
PHE A 298
PHE A 282
THR A 179
 None
 1.41A 3n23A-4pdxA:
undetectable		 3n23A-4pdxA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 11 GLN A 127
ASP A 149
PHE A 298
PHE A 282
THR A 179
 None
 1.41A 3n23C-4pdxA:
undetectable		 3n23C-4pdxA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 4 LEU A 250
GLY A 249
GLY A 251
THR A 356
 None
 0.94A 3si7A-4pdxA:
undetectable		 3si7A-4pdxA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 7 ASP A  60
GLN A  57
ILE A 112
TRP A 357
 None
 1.27A 4ii8A-4pdxA:
undetectable		 4ii8A-4pdxA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 7 ALA A 514
LEU A 250
THR A 515
SER A 233
 None
 1.16A 4iklA-4pdxA:
undetectable
4iklB-4pdxA:
undetectable		 4iklA-4pdxA:
9.92
4iklB-4pdxA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 5 PRO A 155
GLY A 191
ASP A  88
ASP A 162
 None
 0.97A 4n48B-4pdxA:
undetectable		 4n48B-4pdxA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 4 ASN A 248
GLY A 251
ASP A  72
ASP A 132
 None
 1.25A 4n49A-4pdxA:
undetectable		 4n49A-4pdxA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 THR A 340
GLY A 345
ASN A 346
ASP A 342
HIS A 297
 None
 1.39A 4pooB-4pdxA:
undetectable		 4pooB-4pdxA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 GLY A 638
MET A 623
ILE A 635
SER A 605
ALA A 604
 None
 1.08A 4qtuD-4pdxA:
undetectable		 4qtuD-4pdxA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 7 LEU A  76
LEU A  70
LEU A  71
ILE A 136
 None
 0.78A 4ubsA-4pdxA:
undetectable		 4ubsA-4pdxA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 5 LEU A 351
GLU A 349
LEU A 341
HIS A 297
 None
 1.36A 4xi3B-4pdxA:
undetectable		 4xi3B-4pdxA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		4 / 5 LYS A 363
ILE A 365
HIS A 364
VAL A 359
 None
 1.01A 5jmnA-4pdxA:
undetectable		 5jmnA-4pdxA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 ILE A 146
ILE A 177
VAL A 139
THR A 137
ASN A 135
 None
 1.20A 5lg3J-4pdxA:
undetectable		 5lg3J-4pdxA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		3 / 3 GLU A 140
ARG A 168
TYR A 126
 None
 0.66A 5trqB-4pdxA:
undetectable		 5trqB-4pdxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 ALA A 156
PRO A 155
GLY A 191
GLY A 117
ASP A 162
 None
 0.94A 5wwsA-4pdxA:
undetectable		 5wwsA-4pdxA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS
(Escherichia
coli) 		5 / 12 ALA A 156
PRO A 155
GLY A 191
GLY A 117
ASP A 162
 None
 0.95A 5wwsB-4pdxA:
undetectable		 5wwsB-4pdxA:
22.57