SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pe2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_B_DVAB8_0 (GRAMICIDIN A)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	3 / 3	TRP A 158 VAL A 259 TRP A 340	None None MAL A 601 (-3.8A)	1.28A	1c4dA-4pe2A: undetectable 1c4dB-4pe2A: undetectable	1c4dA-4pe2A: 5.21 1c4dB-4pe2A: 5.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E06_A_IPBA600_0 (ODORANT-BINDING PROTEIN)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	4 / 6	VAL A 8 VAL A 50 ILE A 60 ASN A 267	None	0.96A	1e06A-4pe2A: undetectable	1e06A-4pe2A: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LHV_A_NOGA301_1 (SEX HORMONE-BINDING GLOBULIN)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	4 / 8	SER A 255 THR A 225 ASN A 150 LEU A 247	None	1.01A	1lhvA-4pe2A: undetectable	1lhvA-4pe2A: 16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_A_SAMA2001_1 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	4 / 7	TYR A 491 GLY A 442 THR A 489 ASP A 448	None	0.97A	2g70A-4pe2A: undetectable	2g70A-4pe2A: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_B_SAMB2002_1 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	4 / 7	TYR A 491 GLY A 442 THR A 489 ASP A 448	None	0.96A	2g70B-4pe2A: undetectable	2g70B-4pe2A: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_C_VIAC903_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 12	LEU A 262 ILE A 108 VAL A 97 LEU A 76 ILE A 79	None	0.96A	2h42C-4pe2A: undetectable	2h42C-4pe2A: 20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B6H_A_MXDA551_1 (PROSTACYCLIN SYNTHASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	4 / 6	ALA A 188 LEU A 192 ALA A 346 THR A 345	None	0.89A	3b6hA-4pe2A: undetectable	3b6hA-4pe2A: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B6H_B_MXDB551_1 (PROSTACYCLIN SYNTHASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	4 / 6	ALA A 188 LEU A 192 ALA A 346 THR A 345	None	0.92A	3b6hB-4pe2A: undetectable	3b6hB-4pe2A: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_A_PM6A301_1 (THIOPURINE S-METHYLTRANSFERASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	4 / 6	PHE A 258 ALA A 162 LEU A 247 PRO A 159	None	0.95A	3bgdA-4pe2A: undetectable	3bgdA-4pe2A: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_C_SVRC507_1 (PHOSPHOLIPASE A2)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	4 / 7	VAL A 110 GLY A 300 PRO A 229 LYS A 305	None	0.68A	3bjwC-4pe2A: undetectable	3bjwC-4pe2A: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H5G_C_LEIC16_0 (COIL SER L16D-PEN)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	4 / 6	LYS A 459 LEU A 460 LYS A 377 GLU A 382	None	1.04A	3h5gB-4pe2A: undetectable 3h5gC-4pe2A: undetectable	3h5gB-4pe2A: 4.46 3h5gC-4pe2A: 4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HS6_A_EPAA1_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 12	VAL A 343 GLY A 187 ALA A 188 LEU A 192 LEU A 160	None	1.05A	3hs6A-4pe2A: undetectable	3hs6A-4pe2A: 21.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JYR_A_ACRA371_1 (MALTOSE-BINDING PERIPLASMIC PROTEIN)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	10 / 12	ASP A 14 LYS A 15 LYS A 42 GLU A 44 GLU A 45 ALA A 63 ASP A 65 ARG A 66 GLU A 111 TRP A 230	MAL A 601 (-3.1A) MAL A 601 (-2.8A) None None None MAL A 601 (-3.3A) MAL A 601 (-2.9A) MAL A 601 (-3.8A) MAL A 601 (-3.1A) MAL A 601 (-4.5A)	0.72A	3jyrA-4pe2A: 54.3	3jyrA-4pe2A: 72.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JYR_A_ACRA371_1 (MALTOSE-BINDING PERIPLASMIC PROTEIN)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	10 / 12	ASP A 14 LYS A 15 LYS A 42 GLU A 44 GLU A 45 ALA A 63 ASP A 65 GLU A 111 PRO A 154 TRP A 230	MAL A 601 (-3.1A) MAL A 601 (-2.8A) None None None MAL A 601 (-3.3A) MAL A 601 (-2.9A) MAL A 601 (-3.1A) MAL A 601 (-3.5A) MAL A 601 (-4.5A)	0.44A	3jyrA-4pe2A: 54.3	3jyrA-4pe2A: 72.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JYR_A_ACRA371_2 (MALTOSE-BINDING PERIPLASMIC PROTEIN)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	7 / 7	ASN A 12 TRP A 62 GLU A 153 TYR A 155 MET A 330 TRP A 340 ARG A 344	MAL A 601 (-4.5A) MAL A 601 (-4.5A) MAL A 601 (-3.6A) MAL A 601 (-3.9A) MAL A 601 ( 4.3A) MAL A 601 (-3.8A) None	0.30A	3jyrA-4pe2A: 54.3	3jyrA-4pe2A: 72.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MG0_V_BO2V1401_1 (PROTEASOME COMPONENT PUP1 PROTEASOME COMPONENT PUP3)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 11	GLN A 365 ALA A 364 ALA A 162 GLY A 166 ALA A 188	None	1.01A	3mg0V-4pe2A: undetectable 3mg0W-4pe2A: undetectable	3mg0V-4pe2A: 20.40 3mg0W-4pe2A: 18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8Y_B_DIFB585_1 (PROSTAGLANDIN G/H SYNTHASE 1)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 12	VAL A 196 LEU A 160 GLY A 187 ALA A 188 LEU A 361	None	1.01A	3n8yB-4pe2A: undetectable	3n8yB-4pe2A: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_B_RTZB1_1 (CYTOCHROME P450 2D6)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 12	PHE A 156 GLY A 300 LEU A 299 GLU A 111 ALA A 231	None None None MAL A 601 (-3.1A) None	0.85A	3tbgB-4pe2A: undetectable	3tbgB-4pe2A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_D_RTZD1_1 (CYTOCHROME P450 2D6)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 12	PHE A 156 GLY A 300 LEU A 299 GLU A 111 ALA A 231	None None None MAL A 601 (-3.1A) None	0.83A	3tbgD-4pe2A: undetectable	3tbgD-4pe2A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VWQ_A_ACAA601_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 12	ALA A 231 TYR A 17 TYR A 210 ASN A 234 GLY A 228	None	1.36A	3vwqA-4pe2A: undetectable	3vwqA-4pe2A: 23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VWR_A_ACAA601_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 11	ALA A 231 ASP A 296 TYR A 210 ASN A 234 GLY A 228	None	1.36A	3vwrA-4pe2A: undetectable	3vwrA-4pe2A: 22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_G_TMQG202_1 (DIHYDROFOLATE REDUCTASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 12	ILE A 266 ALA A 105 LEU A 20 VAL A 23 ILE A 59	None	1.11A	4m2xG-4pe2A: undetectable	4m2xG-4pe2A: 15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N48_A_SAMA601_1 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	4 / 5	ASN A 267 ALA A 51 GLY A 56 ASP A 14	None None None MAL A 601 (-3.1A)	0.98A	4n48A-4pe2A: undetectable	4n48A-4pe2A: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_B_NPSB602_1 (SERUM ALBUMIN)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 9	ALA A 264 ALA A 105 LEU A 103 LEU A 262 VAL A 261	None	1.16A	4or0B-4pe2A: undetectable	4or0B-4pe2A: 24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WCX_C_SAMC503_0 (BIOTIN AND THIAMIN SYNTHESIS ASSOCIATED)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	5 / 12	TYR A 307 GLY A 19 GLU A 22 LEU A 311 ALA A 109	None	1.26A	4wcxC-4pe2A: undetectable	4wcxC-4pe2A: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W4Z_A_RBFA502_1 (RIBOFLAVIN LYASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	6 / 12	ALA A 342 ALA A 338 GLY A 166 ALA A 188 PHE A 169 VAL A 181	None	1.34A	5w4zA-4pe2A: undetectable	5w4zA-4pe2A: 10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W4Z_B_RBFB502_1 (RIBOFLAVIN LYASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	6 / 12	ALA A 342 ALA A 338 GLY A 166 ALA A 188 PHE A 169 VAL A 181	None	1.36A	5w4zB-4pe2A: undetectable	5w4zB-4pe2A: 10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA603_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	3 / 3	TYR A 155 ASN A 227 LEU A 113	MAL A 601 (-3.9A) None None	0.83A	6b58A-4pe2A: undetectable	6b58A-4pe2A: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BM5_A_SAMA1301_0 (METHIONINE SYNTHASE)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	5 / 11	PRO A 133 GLU A 130 PRO A 254 ALA A 163 PRO A 159	None	1.41A	6bm5A-4pe2A: undetectable	6bm5A-4pe2A: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6I_A_8PRA509_1 (ENVELOPE GLYCOPROTEIN,GP,GP1 ENVELOPE GLYCOPROTEIN)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Clostridioides difficile; Escherichia coli)	5 / 12	VAL A 388 LEU A 494 ALA A 391 LEU A 430 LEU A 439	None	1.12A	6f6iA-4pe2A: undetectable 6f6iB-4pe2A: undetectable	6f6iA-4pe2A: 10.62 6f6iB-4pe2A: 10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_H_BO2H301_0 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-3)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	5 / 12	GLN A 365 ALA A 364 ALA A 162 GLY A 166 ALA A 188	None	0.95A	6hwdH-4pe2A: undetectable 6hwdI-4pe2A: undetectable	6hwdH-4pe2A: 9.05 6hwdI-4pe2A: 11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_V_BO2V301_0 (PROTEASOME SUBUNIT BETA TYPE-2)	4pe2	MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYP E N-TERMINAL CLEAVAGE/METHYLATION DOMAIN PROTEIN (Escherichia coli; Clostridioides difficile)	5 / 11	GLN A 365 ALA A 364 ALA A 162 GLY A 166 ALA A 188	None	0.95A	6hwdV-4pe2A: undetectable	6hwdV-4pe2A: 9.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C4D_B_DVAB8_0","GRAMICIDIN A","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",3,"TRP A 158;VAL A 259;TRP A 340","None;None;MAL A 601 (-3.8A)","1.28A","1c4dA-4pe2A:undetectable;1c4dB-4pe2A:undetectable","1c4dA-4pe2A:5.21;1c4dB-4pe2A:5.21"],["1E06_A_IPBA600_0","ODORANT-BINDING PROTEIN","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",4,"VAL A   8;VAL A  50;ILE A  60;ASN A 267","None","0.96A","1e06A-4pe2A:undetectable","1e06A-4pe2A:15.22"],["1LHV_A_NOGA301_1","SEX HORMONE-BINDING GLOBULIN","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",4,"SER A 255;THR A 225;ASN A 150;LEU A 247","None","1.01A","1lhvA-4pe2A:undetectable","1lhvA-4pe2A:16.30"],["2G70_A_SAMA2001_1","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",4,"TYR A 491;GLY A 442;THR A 489;ASP A 448","None","0.97A","2g70A-4pe2A:undetectable","2g70A-4pe2A:20.30"],["2G70_B_SAMB2002_1","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",4,"TYR A 491;GLY A 442;THR A 489;ASP A 448","None","0.96A","2g70B-4pe2A:undetectable","2g70B-4pe2A:20.30"],["2H42_C_VIAC903_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"LEU A 262;ILE A 108;VAL A  97;LEU A  76;ILE A  79","None","0.96A","2h42C-4pe2A:undetectable","2h42C-4pe2A:20.15"],["3B6H_A_MXDA551_1","PROSTACYCLIN SYNTHASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",4,"ALA A 188;LEU A 192;ALA A 346;THR A 345","None","0.89A","3b6hA-4pe2A:undetectable","3b6hA-4pe2A:23.13"],["3B6H_B_MXDB551_1","PROSTACYCLIN SYNTHASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",4,"ALA A 188;LEU A 192;ALA A 346;THR A 345","None","0.92A","3b6hB-4pe2A:undetectable","3b6hB-4pe2A:23.13"],["3BGD_A_PM6A301_1","THIOPURINE S-METHYLTRANSFERASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",4,"PHE A 258;ALA A 162;LEU A 247;PRO A 159","None","0.95A","3bgdA-4pe2A:undetectable","3bgdA-4pe2A:19.30"],["3BJW_C_SVRC507_1","PHOSPHOLIPASE A2","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",4,"VAL A 110;GLY A 300;PRO A 229;LYS A 305","None","0.68A","3bjwC-4pe2A:undetectable","3bjwC-4pe2A:14.29"],["3H5G_C_LEIC16_0","COIL SER L16D-PEN","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",4,"LYS A 459;LEU A 460;LYS A 377;GLU A 382","None","1.04A","3h5gB-4pe2A:undetectable;3h5gC-4pe2A:undetectable","3h5gB-4pe2A:4.46;3h5gC-4pe2A:4.46"],["3HS6_A_EPAA1_1","PROSTAGLANDIN G\/H SYNTHASE 2","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"VAL A 343;GLY A 187;ALA A 188;LEU A 192;LEU A 160","None","1.05A","3hs6A-4pe2A:undetectable","3hs6A-4pe2A:21.28"],["3JYR_A_ACRA371_1","MALTOSE-BINDING PERIPLASMIC PROTEIN","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",10,"ASP A  14;LYS A  15;LYS A  42;GLU A  44;GLU A  45;ALA A  63;ASP A  65;ARG A  66;GLU A 111;TRP A 230","MAL A 601 (-3.1A);MAL A 601 (-2.8A);None;None;None;MAL A 601 (-3.3A);MAL A 601 (-2.9A);MAL A 601 (-3.8A);MAL A 601 (-3.1A);MAL A 601 (-4.5A)","0.72A","3jyrA-4pe2A:54.3","3jyrA-4pe2A:72.92"],["3JYR_A_ACRA371_1","MALTOSE-BINDING PERIPLASMIC PROTEIN","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",10,"ASP A  14;LYS A  15;LYS A  42;GLU A  44;GLU A  45;ALA A  63;ASP A  65;GLU A 111;PRO A 154;TRP A 230","MAL A 601 (-3.1A);MAL A 601 (-2.8A);None;None;None;MAL A 601 (-3.3A);MAL A 601 (-2.9A);MAL A 601 (-3.1A);MAL A 601 (-3.5A);MAL A 601 (-4.5A)","0.44A","3jyrA-4pe2A:54.3","3jyrA-4pe2A:72.92"],["3JYR_A_ACRA371_2","MALTOSE-BINDING PERIPLASMIC PROTEIN","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",7,"ASN A  12;TRP A  62;GLU A 153;TYR A 155;MET A 330;TRP A 340;ARG A 344","MAL A 601 (-4.5A);MAL A 601 (-4.5A);MAL A 601 (-3.6A);MAL A 601 (-3.9A);MAL A 601 ( 4.3A);MAL A 601 (-3.8A);None","0.30A","3jyrA-4pe2A:54.3","3jyrA-4pe2A:72.92"],["3MG0_V_BO2V1401_1","PROTEASOME COMPONENT PUP1;PROTEASOME COMPONENT PUP3","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"GLN A 365;ALA A 364;ALA A 162;GLY A 166;ALA A 188","None","1.01A","3mg0V-4pe2A:undetectable;3mg0W-4pe2A:undetectable","3mg0V-4pe2A:20.40;3mg0W-4pe2A:18.13"],["3N8Y_B_DIFB585_1","PROSTAGLANDIN G\/H SYNTHASE 1","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"VAL A 196;LEU A 160;GLY A 187;ALA A 188;LEU A 361","None","1.01A","3n8yB-4pe2A:undetectable","3n8yB-4pe2A:21.11"],["3TBG_B_RTZB1_1","CYTOCHROME P450 2D6","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"PHE A 156;GLY A 300;LEU A 299;GLU A 111;ALA A 231","None;None;None;MAL A 601 (-3.1A);None","0.85A","3tbgB-4pe2A:undetectable","3tbgB-4pe2A:20.74"],["3TBG_D_RTZD1_1","CYTOCHROME P450 2D6","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"PHE A 156;GLY A 300;LEU A 299;GLU A 111;ALA A 231","None;None;None;MAL A 601 (-3.1A);None","0.83A","3tbgD-4pe2A:undetectable","3tbgD-4pe2A:20.74"],["3VWQ_A_ACAA601_1","6-AMINOHEXANOATE-DIMER HYDROLASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"ALA A 231;TYR A  17;TYR A 210;ASN A 234;GLY A 228","None","1.36A","3vwqA-4pe2A:undetectable","3vwqA-4pe2A:23.03"],["3VWR_A_ACAA601_1","6-AMINOHEXANOATE-DIMER HYDROLASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"ALA A 231;ASP A 296;TYR A 210;ASN A 234;GLY A 228","None","1.36A","3vwrA-4pe2A:undetectable","3vwrA-4pe2A:22.84"],["4M2X_G_TMQG202_1","DIHYDROFOLATE REDUCTASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"ILE A 266;ALA A 105;LEU A  20;VAL A  23;ILE A  59","None","1.11A","4m2xG-4pe2A:undetectable","4m2xG-4pe2A:15.89"],["4N48_A_SAMA601_1","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",4,"ASN A 267;ALA A  51;GLY A  56;ASP A  14","None;None;None;MAL A 601 (-3.1A)","0.98A","4n48A-4pe2A:undetectable","4n48A-4pe2A:21.79"],["4OR0_B_NPSB602_1","SERUM ALBUMIN","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"ALA A 264;ALA A 105;LEU A 103;LEU A 262;VAL A 261","None","1.16A","4or0B-4pe2A:undetectable","4or0B-4pe2A:24.13"],["4WCX_C_SAMC503_0","BIOTIN AND THIAMIN SYNTHESIS ASSOCIATED","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",5,"TYR A 307;GLY A  19;GLU A  22;LEU A 311;ALA A 109","None","1.26A","4wcxC-4pe2A:undetectable","4wcxC-4pe2A:22.22"],["5W4Z_A_RBFA502_1","RIBOFLAVIN LYASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",6,"ALA A 342;ALA A 338;GLY A 166;ALA A 188;PHE A 169;VAL A 181","None","1.34A","5w4zA-4pe2A:undetectable","5w4zA-4pe2A:10.14"],["5W4Z_B_RBFB502_1","RIBOFLAVIN LYASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",6,"ALA A 342;ALA A 338;GLY A 166;ALA A 188;PHE A 169;VAL A 181","None","1.36A","5w4zB-4pe2A:undetectable","5w4zB-4pe2A:10.14"],["6B58_A_ACTA603_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",3,"TYR A 155;ASN A 227;LEU A 113","MAL A 601 (-3.9A);None;None","0.83A","6b58A-4pe2A:undetectable","6b58A-4pe2A:22.22"],["6BM5_A_SAMA1301_0","METHIONINE SYNTHASE","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",5,"PRO A 133;GLU A 130;PRO A 254;ALA A 163;PRO A 159","None","1.41A","6bm5A-4pe2A:undetectable","6bm5A-4pe2A:22.20"],["6F6I_A_8PRA509_1","ENVELOPE GLYCOPROTEIN,GP,GP1;ENVELOPE GLYCOPROTEIN","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Clostridioides difficile;Escherichia coli",5,"VAL A 388;LEU A 494;ALA A 391;LEU A 430;LEU A 439","None","1.12A","6f6iA-4pe2A:undetectable;6f6iB-4pe2A:undetectable","6f6iA-4pe2A:10.62;6f6iB-4pe2A:10.12"],["6HWD_H_BO2H301_0","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-3","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",5,"GLN A 365;ALA A 364;ALA A 162;GLY A 166;ALA A 188","None","0.95A","6hwdH-4pe2A:undetectable;6hwdI-4pe2A:undetectable","6hwdH-4pe2A:9.05;6hwdI-4pe2A:11.25"],["6HWD_V_BO2V301_0","PROTEASOME SUBUNIT BETA TYPE-2","4pe2","MALTOSE ABC TRANSPORTER PERIPLASMIC PROTEIN,PREPILIN-TYPE N-TERMINAL CLEAVAGE\/METHYLATION DOMAIN PROTEIN","Escherichia coli;Clostridioides difficile",5,"GLN A 365;ALA A 364;ALA A 162;GLY A 166;ALA A 188","None","0.95A","6hwdV-4pe2A:undetectable","6hwdV-4pe2A:9.05"]]