SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pe8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		5 / 12 GLU A  91
HIS A  62
HIS A 127
ASP A 203
PRO A 205
 None
 1.46A 1ituA-4pe8A:
13.5		 1ituA-4pe8A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		5 / 12 GLU A  91
HIS A  62
HIS A 127
HIS A 152
PRO A 205
 None
 1.36A 1ituA-4pe8A:
13.5		 1ituA-4pe8A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		5 / 12 PRO A  63
GLY A  36
SER A  66
GLY A  90
GLY A  60
 None
 0.84A 1uakA-4pe8A:
undetectable		 1uakA-4pe8A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		4 / 6 ASP A 130
THR A 157
GLU A 160
GLU A 185
 None
 1.23A 2dttB-4pe8A:
undetectable
2dttC-4pe8A:
undetectable		 2dttB-4pe8A:
19.07
2dttC-4pe8A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		5 / 12 LEU A 198
LEU A 199
GLY A 172
MET A 161
VAL A 165
 None
 1.36A 2q7lA-4pe8A:
undetectable		 2q7lA-4pe8A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		3 / 3 PRO A 209
LEU A 208
ARG A 220
 None
 0.74A 3aqiB-4pe8A:
undetectable		 3aqiB-4pe8A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		3 / 3 ASP A  95
ARG A 129
ASP A  65
 None
 0.87A 4fp9C-4pe8A:
undetectable		 4fp9C-4pe8A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		3 / 3 ASP A  95
ARG A 129
ASP A  65
 None
 0.89A 4fp9F-4pe8A:
undetectable		 4fp9F-4pe8A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		5 / 11 GLN A 162
ARG A 158
LEU A 189
CYH A 128
HIS A 127
 None
 1.03A 4nqaA-4pe8A:
undetectable		 4nqaA-4pe8A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		3 / 3 ASP A 203
GLY A   5
ASP A   3
 None
 0.69A 4xdtA-4pe8A:
undetectable		 4xdtA-4pe8A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		5 / 12 PRO A  63
GLY A  36
SER A  66
GLY A  90
GLY A  60
 None
 0.85A 5wyqB-4pe8A:
undetectable		 5wyqB-4pe8A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		4 / 8 GLY A   5
LEU A  33
CYH A  55
ALA A  45
 None
 0.78A 5xu8A-4pe8A:
undetectable		 5xu8A-4pe8A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 4pe8 TAT-LINKED QUALITY
CONTROL PROTEIN TATD
(Escherichia
coli) 		5 / 9 ALA A  45
ALA A  59
GLY A  36
ALA A  88
GLY A  90
 None
 1.13A 6bklE-4pe8A:
undetectable
6bklF-4pe8A:
undetectable
6bklG-4pe8A:
undetectable
6bklH-4pe8A:
undetectable		 6bklE-4pe8A:
7.81
6bklF-4pe8A:
7.81
6bklG-4pe8A:
7.81
6bklH-4pe8A:
7.81