SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ph0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 4ph0 BLV CAPSID
(Bovine
leukemia
virus) 		5 / 12 LEU A  97
SER A 101
HIS A  70
LEU A  74
ILE A  78
 None
 1.14A 1fmlA-4ph0A:
undetectable		 1fmlA-4ph0A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 4ph0 BLV CAPSID
(Bovine
leukemia
virus) 		5 / 12 LEU A  97
SER A 101
HIS A  70
LEU A  74
ILE A  78
 None
 1.15A 1fmlB-4ph0A:
undetectable		 1fmlB-4ph0A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 4ph0 BLV CAPSID
(Bovine
leukemia
virus) 		3 / 3 LEU A 118
ASN A 115
ARG A  41
 None
 0.85A 2qhfA-4ph0A:
undetectable		 2qhfA-4ph0A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 4ph0 BLV CAPSID
(Bovine
leukemia
virus) 		4 / 8 ARG A  12
LYS A   1
ASP A  53
ALA A  15
 None
 1.18A 2rk8A-4ph0A:
undetectable		 2rk8A-4ph0A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 4ph0 BLV CAPSID
(Bovine
leukemia
virus) 		5 / 12 GLU A  18
LEU A  57
LEU A  54
ILE A  44
ALA A  43
 None
 1.20A 5v0vA-4ph0A:
2.2		 5v0vA-4ph0A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 4ph0 BLV CAPSID
(Bovine
leukemia
virus) 		4 / 6 GLN A 119
TRP A 117
HIS A  70
ALA A 120
 None
 1.25A 6f6jC-4ph0A:
undetectable
6f6jD-4ph0A:
undetectable		 6f6jC-4ph0A:
21.37
6f6jD-4ph0A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 4ph0 BLV CAPSID
(Bovine
leukemia
virus) 		4 / 4 LEU A  54
ASP A  48
PRO A  49
ARG A 110
 None
 1.29A 6fgdA-4ph0A:
undetectable		 6fgdA-4ph0A:
20.53