SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ph8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 4ph8 AGGREGATIVE
ADHERENCE FIMBRIAL
SUBUNIT AGGA
(Escherichia
coli) 		3 / 3 SER A  29
THR A  32
PHE A  36
 None
 0.77A 2x91A-4ph8A:
undetectable		 2x91A-4ph8A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 4ph8 AGGREGATIVE
ADHERENCE FIMBRIAL
SUBUNIT AGGA
(Escherichia
coli) 		4 / 8 ASP A  83
GLY A  85
ALA A  86
ASP A  87
 None
 0.56A 3el0A-4ph8A:
undetectable		 3el0A-4ph8A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 4ph8 AGGREGATIVE
ADHERENCE FIMBRIAL
SUBUNIT AGGA
(Escherichia
coli) 		4 / 7 ASP A  83
GLY A  85
ALA A  86
ASP A  87
 None
 0.53A 3t3cA-4ph8A:
undetectable		 3t3cA-4ph8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4ph8 AGGREGATIVE
ADHERENCE FIMBRIAL
SUBUNIT AGGA
(Escherichia
coli) 		5 / 12 THR A  32
LEU A 153
VAL A 155
GLY A  27
SER A  30
 None
 1.14A 6a94B-4ph8A:
undetectable		 6a94B-4ph8A:
21.48