SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ph9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.41A 1cqeA-4ph9A:
59.1		 1cqeA-4ph9A:
63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.42A 1cqeB-4ph9A:
59.2		 1cqeB-4ph9A:
63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 9 VAL A 117
ARG A 121
VAL A 350
TYR A 356
LEU A 360
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.55A 1eqgA-4ph9A:
59.2		 1eqgA-4ph9A:
63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 11 VAL A 117
ARG A 121
VAL A 350
SER A 354
TYR A 356
LEU A 360
TYR A 386
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.50A 1eqgB-4ph9A:
59.3		 1eqgB-4ph9A:
63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 117
ARG A 121
VAL A 350
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.28A 1eqhA-4ph9A:
59.5		 1eqhA-4ph9A:
63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 117
ARG A 121
VAL A 350
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.32A 1eqhB-4ph9A:
59.5		 1eqhB-4ph9A:
63.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 10 VAL A 117
ARG A 121
PHE A 206
VAL A 229
VAL A 345
TYR A 349
VAL A 350
ASN A 376
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
None
None
None
None
IBP  A 601 (-4.3A)
EDO  A 616 (-4.4A)
IBP  A 601 ( 4.9A)
 0.41A 1fe2A-4ph9A:
58.4		 1fe2A-4ph9A:
63.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 PHE A 206
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
 None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 1.29A 1fe2A-4ph9A:
58.4		 1fe2A-4ph9A:
63.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 PHE A 210
LEU A 353
PHE A 382
TYR A 386
TRP A 388
PHE A 519
GLY A 527
ALA A 528
SER A 531
GLY A 534
LEU A 535
 EDO  A 616 (-3.5A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.8A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
EDO  A 616 (-3.0A)
EDO  A 616 ( 4.4A)
 0.64A 1fe2A-4ph9A:
58.4		 1fe2A-4ph9A:
63.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 PHE A 210
LEU A 353
TYR A 356
PHE A 382
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
GLY A 534
LEU A 535
 EDO  A 616 (-3.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
EDO  A 616 (-3.0A)
EDO  A 616 ( 4.4A)
 0.37A 1fe2A-4ph9A:
58.4		 1fe2A-4ph9A:
63.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 PHE A 206
PHE A 210
LEU A 353
TYR A 356
PHE A 382
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
GLY A 534
LEU A 535
 None
EDO  A 616 (-3.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
EDO  A 616 (-3.0A)
EDO  A 616 ( 4.4A)
 0.53A 1igxA-4ph9A:
58.1		 1igxA-4ph9A:
63.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 PHE A 211
LEU A 353
TYR A 356
PHE A 382
ALA A 528
SER A 531
 HEM  A 602 (-4.6A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 1.50A 1igxA-4ph9A:
58.1		 1igxA-4ph9A:
63.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 PRO A 264
PHE A 286
GLN A 256
VAL A 267
 None
 1.40A 1l2iB-4ph9A:
undetectable		 1l2iB-4ph9A:
18.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 7 VAL A 117
ARG A 121
VAL A 350
LEU A 353
TYR A 356
ALA A 528
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.53A 1pthA-4ph9A:
58.7		 1pthA-4ph9A:
63.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 7 VAL A 117
ARG A 121
VAL A 350
LEU A 353
TYR A 356
ALA A 528
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.53A 1pthB-4ph9A:
58.7		 1pthB-4ph9A:
63.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 10 VAL A 350
LEU A 353
LEU A 385
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.53A 1pxxA-4ph9A:
63.3		 1pxxA-4ph9A:
96.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 9 VAL A 350
LEU A 353
LEU A 385
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.51A 1pxxB-4ph9A:
63.3		 1pxxB-4ph9A:
96.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
LEU A 385
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.51A 1pxxC-4ph9A:
63.4		 1pxxC-4ph9A:
96.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 10 VAL A 350
LEU A 353
TYR A 356
LEU A 385
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.48A 1pxxD-4ph9A:
63.3		 1pxxD-4ph9A:
96.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 PHE A 211
LEU A 391
VAL A 435
PHE A 519
HIS A 389
 HEM  A 602 (-4.6A)
None
None
None
HEM  A 602 (-3.3A)
 1.46A 1q23D-4ph9A:
undetectable
1q23E-4ph9A:
undetectable		 1q23D-4ph9A:
16.57
1q23E-4ph9A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.22A 1v54A-4ph9A:
undetectable
1v54C-4ph9A:
undetectable		 1v54A-4ph9A:
20.29
1v54C-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.22A 1v54N-4ph9A:
undetectable
1v54P-4ph9A:
undetectable		 1v54N-4ph9A:
20.29
1v54P-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 LYS A 115
LEU A 118
GLN A 370
PHE A 362
 None
 1.05A 1v55C-4ph9A:
undetectable
1v55J-4ph9A:
undetectable		 1v55C-4ph9A:
20.75
1v55J-4ph9A:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.24A 1v55A-4ph9A:
undetectable
1v55C-4ph9A:
undetectable		 1v55A-4ph9A:
20.29
1v55C-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_2
(BETA-LACTAMASE
CTX-M-9)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 TYR A 374
PRO A 128
THR A 119
SER A 122
 None
 1.49A 1ymxA-4ph9A:
undetectable		 1ymxA-4ph9A:
20.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.64A 2aylA-4ph9A:
59.3		 2aylA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.45A 2aylA-4ph9A:
59.3		 2aylA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 VAL A 350
LEU A 353
LEU A 360
TYR A 386
TRP A 388
PHE A 519
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.88A 2aylA-4ph9A:
59.3		 2aylA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 VAL A 350
LEU A 353
LEU A 360
TYR A 386
TRP A 388
PHE A 519
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.74A 2aylA-4ph9A:
59.3		 2aylA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.57A 2aylB-4ph9A:
59.4		 2aylB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.32A 2aylB-4ph9A:
59.4		 2aylB-4ph9A:
64.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 8 PHE A 201
LEU A 392
LEU A 409
LEU A 295
 None
HEM  A 602 (-4.2A)
HEM  A 602 ( 4.7A)
None
 0.98A 2bfpA-4ph9A:
undetectable		 2bfpA-4ph9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.21A 2dyrA-4ph9A:
undetectable
2dyrC-4ph9A:
undetectable		 2dyrA-4ph9A:
20.29
2dyrC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 2dyrN-4ph9A:
undetectable
2dyrP-4ph9A:
undetectable		 2dyrN-4ph9A:
20.29
2dyrP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.24A 2dysA-4ph9A:
undetectable
2dysC-4ph9A:
undetectable		 2dysA-4ph9A:
20.29
2dysC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.20A 2dysN-4ph9A:
undetectable
2dysP-4ph9A:
undetectable		 2dysN-4ph9A:
20.29
2dysP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 LYS A 115
LEU A 118
GLN A 370
PHE A 362
 None
 1.04A 2eijC-4ph9A:
undetectable
2eijJ-4ph9A:
undetectable		 2eijC-4ph9A:
20.75
2eijJ-4ph9A:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 2eijA-4ph9A:
undetectable
2eijC-4ph9A:
undetectable		 2eijA-4ph9A:
20.29
2eijC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.24A 2eijN-4ph9A:
undetectable
2eijP-4ph9A:
undetectable		 2eijN-4ph9A:
20.29
2eijP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.27A 2eikA-4ph9A:
undetectable
2eikC-4ph9A:
undetectable		 2eikA-4ph9A:
20.29
2eikC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 2eikN-4ph9A:
undetectable
2eikP-4ph9A:
undetectable		 2eikN-4ph9A:
20.29
2eikP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 2eilA-4ph9A:
undetectable
2eilC-4ph9A:
undetectable		 2eilA-4ph9A:
20.29
2eilC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.22A 2eilN-4ph9A:
undetectable
2eilP-4ph9A:
undetectable		 2eilN-4ph9A:
20.29
2eilP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.26A 2eimA-4ph9A:
undetectable
2eimC-4ph9A:
undetectable		 2eimA-4ph9A:
20.29
2eimC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 LYS A 115
LEU A 118
GLN A 370
PHE A 362
 None
 1.03A 2eimC-4ph9A:
undetectable
2eimJ-4ph9A:
undetectable		 2eimC-4ph9A:
20.75
2eimJ-4ph9A:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.29A 2eimN-4ph9A:
undetectable
2eimP-4ph9A:
undetectable		 2eimN-4ph9A:
20.29
2eimP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 LYS A 115
LEU A 118
GLN A 370
PHE A 362
 None
 1.02A 2einC-4ph9A:
undetectable
2einJ-4ph9A:
undetectable		 2einC-4ph9A:
20.75
2einJ-4ph9A:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.28A 2einA-4ph9A:
undetectable
2einC-4ph9A:
undetectable		 2einA-4ph9A:
20.29
2einC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.31A 2einN-4ph9A:
undetectable
2einP-4ph9A:
undetectable		 2einN-4ph9A:
20.29
2einP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 LEU A 535
GLY A 228
ILE A 338
ILE A 342
 EDO  A 616 ( 4.4A)
EDO  A 616 ( 4.5A)
None
None
 0.82A 2q9rA-4ph9A:
undetectable		 2q9rA-4ph9A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 8 LEU A 360
SER A 120
VAL A 524
GLY A 527
 IBP  A 601 ( 4.7A)
BOG  A 604 (-2.8A)
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
 1.04A 2qd5B-4ph9A:
undetectable		 2qd5B-4ph9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 TYR A 505
LEU A 509
ALA A 449
VAL A 448
PHE A 519
 None
None
None
HEM  A 602 (-4.2A)
None
 1.17A 2qo4A-4ph9A:
undetectable		 2qo4A-4ph9A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 TYR A 505
LEU A 509
ALA A 449
VAL A 448
PHE A 519
 None
None
None
HEM  A 602 (-4.2A)
None
 1.18A 2qo6A-4ph9A:
undetectable		 2qo6A-4ph9A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 8 LEU A 464
LEU A 504
PRO A 506
LEU A 509
ALA A 436
 None
 1.19A 2vcvP-4ph9A:
undetectable		 2vcvP-4ph9A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 GLY A 289
ILE A 234
ARG A 334
ALA A 303
GLU A 237
 None
 1.27A 2vdvE-4ph9A:
undetectable		 2vdvE-4ph9A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 11 GLY A 289
ILE A 234
ARG A 334
ALA A 303
GLU A 237
 None
 1.28A 2vdvF-4ph9A:
undetectable		 2vdvF-4ph9A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.19A 2y69A-4ph9A:
undetectable
2y69C-4ph9A:
undetectable		 2y69A-4ph9A:
20.29
2y69C-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 GLN A 331
THR A 332
GLY A 325
GLY A 251
ASP A 250
 None
 1.24A 2zw9B-4ph9A:
undetectable		 2zw9B-4ph9A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 2zxwA-4ph9A:
undetectable
2zxwC-4ph9A:
undetectable		 2zxwA-4ph9A:
20.29
2zxwC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 2zxwN-4ph9A:
undetectable
2zxwP-4ph9A:
undetectable		 2zxwN-4ph9A:
20.29
2zxwP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 11 ASN A  39
ILE A 499
THR A 483
VAL A 510
PRO A 506
 None
 1.09A 3a51A-4ph9A:
undetectable		 3a51A-4ph9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 ASN A  39
ILE A 499
THR A 483
VAL A 510
PRO A 506
 None
 1.08A 3a51B-4ph9A:
2.0		 3a51B-4ph9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 ASN A  39
ILE A 499
THR A 483
VAL A 510
PRO A 506
 None
 1.11A 3a51C-4ph9A:
undetectable		 3a51C-4ph9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 ASN A  39
ILE A 499
THR A 483
VAL A 510
PRO A 506
 None
 1.10A 3a51D-4ph9A:
undetectable		 3a51D-4ph9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 ASN A  39
ILE A 499
THR A 483
VAL A 510
PRO A 506
 None
 1.04A 3a51E-4ph9A:
2.1		 3a51E-4ph9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 3abkA-4ph9A:
undetectable
3abkC-4ph9A:
undetectable		 3abkA-4ph9A:
20.29
3abkC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 3abkN-4ph9A:
undetectable
3abkP-4ph9A:
undetectable		 3abkN-4ph9A:
20.29
3abkP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 8 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.20A 3abmA-4ph9A:
undetectable
3abmC-4ph9A:
undetectable
3abmP-4ph9A:
undetectable		 3abmA-4ph9A:
20.29
3abmC-4ph9A:
20.75
3abmP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.22A 3abmN-4ph9A:
undetectable
3abmP-4ph9A:
undetectable		 3abmN-4ph9A:
20.29
3abmP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 3ag1A-4ph9A:
undetectable
3ag1C-4ph9A:
undetectable		 3ag1A-4ph9A:
20.29
3ag1C-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.21A 3ag1N-4ph9A:
undetectable
3ag1P-4ph9A:
undetectable		 3ag1N-4ph9A:
20.29
3ag1P-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.24A 3ag2A-4ph9A:
undetectable
3ag2C-4ph9A:
undetectable		 3ag2A-4ph9A:
20.29
3ag2C-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.22A 3ag2N-4ph9A:
undetectable
3ag2P-4ph9A:
undetectable		 3ag2N-4ph9A:
20.29
3ag2P-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 3ag3A-4ph9A:
undetectable
3ag3C-4ph9A:
undetectable		 3ag3A-4ph9A:
20.29
3ag3C-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 3ag3N-4ph9A:
undetectable
3ag3P-4ph9A:
undetectable		 3ag3N-4ph9A:
20.29
3ag3P-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.26A 3ag4A-4ph9A:
undetectable
3ag4C-4ph9A:
undetectable		 3ag4A-4ph9A:
20.29
3ag4C-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 3ag4N-4ph9A:
undetectable
3ag4P-4ph9A:
undetectable		 3ag4N-4ph9A:
20.29
3ag4P-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 PHE A 210
PHE A 199
LEU A 391
HIS A 387
TYR A 349
 EDO  A 616 (-3.5A)
None
None
HEM  A 602 (-3.7A)
None
 1.19A 3apvB-4ph9A:
undetectable		 3apvB-4ph9A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.27A 3asnA-4ph9A:
undetectable
3asnC-4ph9A:
undetectable		 3asnA-4ph9A:
20.29
3asnC-4ph9A:
20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 117
VAL A 350
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 535
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
EDO  A 616 ( 4.4A)
 0.37A 3hs6A-4ph9A:
63.3		 3hs6A-4ph9A:
99.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 117
VAL A 350
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.62A 3hs6A-4ph9A:
63.3		 3hs6A-4ph9A:
99.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 PHE A 210
GLY A 228
TYR A 356
ASN A 376
ILE A 378
PHE A 382
ALA A 528
SER A 531
GLY A 534
 EDO  A 616 (-3.5A)
EDO  A 616 ( 4.5A)
IBP  A 601 (-4.5A)
EDO  A 616 (-4.4A)
None
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
EDO  A 616 (-3.0A)
 0.72A 3hs6B-4ph9A:
63.6		 3hs6B-4ph9A:
99.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 PHE A 210
GLY A 228
TYR A 356
ASN A 376
ILE A 378
PHE A 382
TYR A 386
GLY A 527
ALA A 528
GLY A 534
LEU A 535
 EDO  A 616 (-3.5A)
EDO  A 616 ( 4.5A)
IBP  A 601 (-4.5A)
EDO  A 616 (-4.4A)
None
None
IBP  A 601 (-4.8A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
EDO  A 616 (-3.0A)
EDO  A 616 ( 4.4A)
 0.38A 3hs6B-4ph9A:
63.6		 3hs6B-4ph9A:
99.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 PHE A 211
TYR A 356
ILE A 378
PHE A 382
ALA A 528
SER A 531
 HEM  A 602 (-4.6A)
IBP  A 601 (-4.5A)
None
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 1.29A 3hs6B-4ph9A:
63.6		 3hs6B-4ph9A:
99.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 PHE A 211
TYR A 356
ILE A 378
PHE A 382
GLY A 527
ALA A 528
 HEM  A 602 (-4.6A)
IBP  A 601 (-4.5A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
 1.37A 3hs6B-4ph9A:
63.6		 3hs6B-4ph9A:
99.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 12 GLN A 193
VAL A 350
LEU A 353
TRP A 388
PHE A 519
GLY A 527
SER A 531
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 ( 3.3A)
 0.93A 3kk6A-4ph9A:
57.1		 3kk6A-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 GLN A 193
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TRP A 388
GLY A 527
ALA A 528
SER A 531
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.71A 3kk6A-4ph9A:
57.1		 3kk6A-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 12 GLN A 193
VAL A 350
LEU A 353
TRP A 388
PHE A 519
GLY A 527
SER A 531
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 ( 3.3A)
 0.90A 3kk6B-4ph9A:
56.8		 3kk6B-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 HIS A  90
GLN A 193
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TRP A 388
GLY A 527
SER A 531
 None
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-3.9A)
IBP  A 601 ( 3.3A)
 0.64A 3kk6B-4ph9A:
56.8		 3kk6B-4ph9A:
64.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 HIS A 205
PHE A 199
PHE A 581
 None
 0.63A 3lk0D-4ph9A:
1.0		 3lk0D-4ph9A:
10.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 HIS A  90
GLN A 193
VAL A 350
TYR A 356
LEU A 360
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
None
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.53A 3ln1A-4ph9A:
63.8		 3ln1A-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 HIS A  90
GLN A 193
VAL A 350
TYR A 356
LEU A 360
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
None
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.53A 3ln1B-4ph9A:
63.9		 3ln1B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 HIS A  90
VAL A 350
TYR A 356
LEU A 360
TYR A 386
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.52A 3ln1C-4ph9A:
63.8		 3ln1C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 7 ARG A 121
GLN A 193
SER A 354
LEU A 385
ARG A 514
ILE A 518
PHE A 519
 BOG  A 604 ( 3.7A)
None
None
None
None
None
None
 0.42A 3ln1C-4ph9A:
63.8		 3ln1C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 7 GLN A 193
LEU A 508
ARG A 514
ILE A 518
PHE A 519
 None
 1.10A 3ln1C-4ph9A:
63.8		 3ln1C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 HIS A  90
GLN A 193
VAL A 350
SER A 354
TYR A 356
LEU A 360
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 None
None
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.32A 3ln1D-4ph9A:
63.8		 3ln1D-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 5 ARG A 121
LEU A 385
ARG A 514
ILE A 518
PHE A 519
 BOG  A 604 ( 3.7A)
None
None
None
None
 0.43A 3ln1D-4ph9A:
63.8		 3ln1D-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 LEU A 508
ARG A 514
ILE A 518
PHE A 519
 None
 1.00A 3ln1D-4ph9A:
63.8		 3ln1D-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 117
ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.47A 3n8wA-4ph9A:
58.7		 3n8wA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 HIS A  90
ARG A 121
LEU A 353
TYR A 356
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
BOG  A 604 ( 3.7A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.62A 3n8xA-4ph9A:
11.5		 3n8xA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 HIS A  90
LEU A 353
TYR A 356
TYR A 386
TRP A 388
PHE A 519
GLY A 527
SER A 531
LEU A 532
 None
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.72A 3n8xA-4ph9A:
11.5		 3n8xA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 HIS A  90
ARG A 121
LEU A 353
TYR A 356
LEU A 360
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
BOG  A 604 ( 3.7A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.61A 3n8xB-4ph9A:
57.9		 3n8xB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 LEU A 353
TYR A 356
LEU A 360
TRP A 388
PHE A 519
GLY A 527
SER A 531
LEU A 532
 IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.73A 3n8xB-4ph9A:
57.9		 3n8xB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 VAL A 117
VAL A 350
SER A 354
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
None
 0.12A 3n8xB-4ph9A:
57.9		 3n8xB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 11 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.80A 3n8yA-4ph9A:
34.1		 3n8yA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 11 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.61A 3n8yA-4ph9A:
34.1		 3n8yA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 345
VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
GLY A 527
ALA A 528
LEU A 532
LEU A 535
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
EDO  A 616 ( 4.4A)
 0.47A 3n8yB-4ph9A:
32.9		 3n8yB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 VAL A 350
LEU A 353
TYR A 356
ALA A 528
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-3.4A)
 0.45A 3n8yB-4ph9A:
32.9		 3n8yB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 117
ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.55A 3n8zA-4ph9A:
58.5		 3n8zA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 385
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.57A 3n8zB-4ph9A:
58.6		 3n8zB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.65A 3nt1A-4ph9A:
64.9		 3nt1A-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.46A 3nt1A-4ph9A:
64.9		 3nt1A-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
 BOG  A 604 ( 3.7A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.70A 3nt1B-4ph9A:
65.0		 3nt1B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.46A 3nt1B-4ph9A:
65.0		 3nt1B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 117
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.54A 3pghA-4ph9A:
63.3		 3pghA-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 117
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.37A 3pghA-4ph9A:
63.3		 3pghA-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 11 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
MET A 523
VAL A 524
GLY A 527
ALA A 528
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
 0.42A 3pghB-4ph9A:
25.4		 3pghB-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 117
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.52A 3pghC-4ph9A:
63.3		 3pghC-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.56A 3pghD-4ph9A:
63.3		 3pghD-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 117
ARG A 121
VAL A 350
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.43A 3rr3A-4ph9A:
63.6		 3rr3A-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 117
ARG A 121
VAL A 350
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.44A 3rr3B-4ph9A:
63.6		 3rr3B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 117
ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.60A 3rr3C-4ph9A:
63.6		 3rr3C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 117
ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.60A 3rr3D-4ph9A:
63.6		 3rr3D-4ph9A:
99.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 9 LEU A 335
GLY A 226
PRO A 539
ILE A 540
ILE A 338
 None
 1.10A 3s56B-4ph9A:
undetectable		 3s56B-4ph9A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 9 PHE A 201
PHE A 396
ASN A 196
PHE A 427
LEU A 391
 None
 1.31A 3t3sA-4ph9A:
undetectable		 3t3sA-4ph9A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 ARG A 470
PHE A 530
PRO A 529
LEU A 526
 None
 1.47A 3tgvC-4ph9A:
undetectable		 3tgvC-4ph9A:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 TYR A 496
MET A 523
LEU A 509
 None
 0.94A 3vw1D-4ph9A:
undetectable		 3vw1D-4ph9A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 GLY A 298
LEU A 295
GLY A 294
TYR A 410
ASN A 412
PHE A 396
 None
 1.27A 3vywC-4ph9A:
undetectable		 3vywC-4ph9A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 ILE A 565
PHE A 199
TYR A 302
HIS A 233
 None
 1.23A 4a97I-4ph9A:
undetectable		 4a97I-4ph9A:
19.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
LEU A 385
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.70A 4coxA-4ph9A:
62.8		 4coxA-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.59A 4coxA-4ph9A:
62.8		 4coxA-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.25A 4coxA-4ph9A:
62.8		 4coxA-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
LEU A 385
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.69A 4coxB-4ph9A:
62.6		 4coxB-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.58A 4coxB-4ph9A:
62.6		 4coxB-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.26A 4coxB-4ph9A:
62.6		 4coxB-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 ARG A 121
VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.56A 4coxC-4ph9A:
62.6		 4coxC-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
LEU A 385
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.70A 4coxD-4ph9A:
62.8		 4coxD-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.59A 4coxD-4ph9A:
62.8		 4coxD-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.27A 4coxD-4ph9A:
62.8		 4coxD-4ph9A:
99.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 PHE A 206
PHE A 210
TYR A 356
ASN A 376
ILE A 378
PHE A 382
TYR A 386
GLY A 527
ALA A 528
SER A 531
GLY A 534
LEU A 535
 None
EDO  A 616 (-3.5A)
IBP  A 601 (-4.5A)
EDO  A 616 (-4.4A)
None
None
IBP  A 601 (-4.8A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
EDO  A 616 (-3.0A)
EDO  A 616 ( 4.4A)
 0.28A 4e1gA-4ph9A:
64.6		 4e1gA-4ph9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 12 PHE A 211
TYR A 356
ILE A 378
PHE A 382
GLY A 527
ALA A 528
SER A 531
 HEM  A 602 (-4.6A)
IBP  A 601 (-4.5A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 1.31A 4e1gA-4ph9A:
64.6		 4e1gA-4ph9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 5 ARG A 121
VAL A 350
LEU A 353
SER A 354
MET A 523
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
None
 0.20A 4e1gA-4ph9A:
64.6		 4e1gA-4ph9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 ARG A 121
PHE A 206
PHE A 210
TYR A 356
ILE A 378
PHE A 382
TYR A 386
GLY A 527
ALA A 528
SER A 531
GLY A 534
LEU A 535
 BOG  A 604 ( 3.7A)
None
EDO  A 616 (-3.5A)
IBP  A 601 (-4.5A)
None
None
IBP  A 601 (-4.8A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
EDO  A 616 (-3.0A)
EDO  A 616 ( 4.4A)
 0.16A 4e1gB-4ph9A:
64.9		 4e1gB-4ph9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 ARG A 121
PHE A 211
TYR A 356
ILE A 378
PHE A 382
GLY A 527
ALA A 528
SER A 531
 BOG  A 604 ( 3.7A)
HEM  A 602 (-4.6A)
IBP  A 601 (-4.5A)
None
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 1.37A 4e1gB-4ph9A:
64.9		 4e1gB-4ph9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 7 VAL A 345
TYR A 349
VAL A 350
LEU A 353
ASN A 376
MET A 523
VAL A 524
 None
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
EDO  A 616 (-4.4A)
None
IBP  A 601 ( 4.0A)
 0.24A 4e1gB-4ph9A:
64.9		 4e1gB-4ph9A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 SER A 139
HIS A 134
TYR A 137
VAL A 133
 None
 1.33A 4eohB-4ph9A:
undetectable		 4eohB-4ph9A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.47A 4jksA-4ph9A:
undetectable		 4jksA-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.47A 4jksB-4ph9A:
undetectable		 4jksB-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.47A 4jkuA-4ph9A:
undetectable		 4jkuA-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_2
(SUGAR KINASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.47A 4k8cB-4ph9A:
undetectable		 4k8cB-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_2
(SUGAR KINASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.47A 4k8kA-4ph9A:
undetectable		 4k8kA-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.48A 4k8kB-4ph9A:
undetectable		 4k8kB-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.47A 4kalA-4ph9A:
undetectable		 4kalA-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.47A 4kalB-4ph9A:
undetectable		 4kalB-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.47A 4lcaA-4ph9A:
undetectable		 4lcaA-4ph9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 SER A 456
LEU A 179
TYR A 505
PRO A 219
 None
 1.46A 4lcaB-4ph9A:
undetectable		 4lcaB-4ph9A:
21.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 MET A 114
ARG A 121
VAL A 350
LEU A 360
ALA A 528
SER A 531
 None
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.71A 4m11A-4ph9A:
63.5		 4m11A-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 MET A 114
LEU A 118
ARG A 121
ILE A 346
VAL A 350
LEU A 360
TRP A 388
MET A 523
ALA A 528
 None
None
BOG  A 604 ( 3.7A)
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 (-3.4A)
 0.53A 4m11A-4ph9A:
63.5		 4m11A-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 MET A 114
VAL A 117
ARG A 121
ILE A 346
LEU A 353
LEU A 360
TRP A 388
ALA A 528
LEU A 535
 None
BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
None
IBP  A 601 ( 4.7A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-3.4A)
EDO  A 616 ( 4.4A)
 0.71A 4m11B-4ph9A:
63.5		 4m11B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 12 MET A 114
VAL A 117
ARG A 121
ILE A 346
LEU A 353
LEU A 532
LEU A 535
 None
BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
None
IBP  A 601 ( 4.7A)
IBP  A 601 ( 4.9A)
EDO  A 616 ( 4.4A)
 1.24A 4m11B-4ph9A:
63.5		 4m11B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 MET A 114
VAL A 117
ARG A 121
ILE A 346
VAL A 350
LEU A 360
TRP A 388
ALA A 528
LEU A 535
 None
BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-3.4A)
EDO  A 616 ( 4.4A)
 0.53A 4m11B-4ph9A:
63.5		 4m11B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 MET A 114
VAL A 117
ARG A 121
LEU A 353
LEU A 360
TRP A 388
ALA A 528
SER A 531
 None
BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 ( 4.7A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.87A 4m11B-4ph9A:
63.5		 4m11B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 MET A 114
VAL A 117
ARG A 121
LEU A 353
SER A 531
LEU A 532
 None
BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 ( 4.7A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.40A 4m11B-4ph9A:
63.5		 4m11B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 MET A 114
VAL A 117
ARG A 121
VAL A 350
LEU A 360
TRP A 388
ALA A 528
SER A 531
 None
BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.73A 4m11B-4ph9A:
63.5		 4m11B-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 MET A 114
ILE A 346
VAL A 350
LEU A 360
TRP A 388
VAL A 524
ALA A 528
LEU A 535
 None
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
EDO  A 616 ( 4.4A)
 0.36A 4m11C-4ph9A:
63.5		 4m11C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 12 MET A 114
VAL A 117
ILE A 346
VAL A 350
LEU A 360
TRP A 388
LEU A 535
 None
BOG  A 604 (-3.9A)
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
EDO  A 616 ( 4.4A)
 0.57A 4m11C-4ph9A:
63.5		 4m11C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 MET A 114
VAL A 117
VAL A 350
LEU A 360
SER A 531
 None
BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 ( 3.3A)
 0.84A 4m11C-4ph9A:
63.5		 4m11C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 MET A 114
VAL A 350
LEU A 360
VAL A 524
ALA A 528
SER A 531
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.69A 4m11C-4ph9A:
63.5		 4m11C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 LEU A 118
ARG A 121
MET A 523
 None
BOG  A 604 ( 3.7A)
None
 0.56A 4m11C-4ph9A:
63.5		 4m11C-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 MET A 114
LEU A 353
TRP A 388
VAL A 524
ALA A 528
 None
IBP  A 601 ( 4.7A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
 0.74A 4m11D-4ph9A:
63.6		 4m11D-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 MET A 114
VAL A 117
ARG A 121
ILE A 346
VAL A 350
LEU A 360
TRP A 388
VAL A 524
ALA A 528
 None
BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
 0.54A 4m11D-4ph9A:
63.6		 4m11D-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 12 MET A 114
VAL A 117
ARG A 121
VAL A 350
LEU A 360
ALA A 528
SER A 531
 None
BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.78A 4m11D-4ph9A:
63.6		 4m11D-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 6 VAL A 117
LEU A 118
ARG A 121
LEU A 360
MET A 523
 BOG  A 604 (-3.9A)
None
BOG  A 604 ( 3.7A)
IBP  A 601 ( 4.7A)
None
 0.64A 4o1zA-4ph9A:
58.8		 4o1zA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 6 VAL A 117
LEU A 118
LEU A 360
PHE A 519
MET A 523
 BOG  A 604 (-3.9A)
None
IBP  A 601 ( 4.7A)
None
None
 0.77A 4o1zA-4ph9A:
58.8		 4o1zA-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 MET A 114
VAL A 117
LEU A 118
ARG A 121
ILE A 346
VAL A 350
LEU A 360
TRP A 388
PHE A 519
ALA A 528
SER A 531
 None
BOG  A 604 (-3.9A)
None
BOG  A 604 ( 3.7A)
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.77A 4o1zB-4ph9A:
58.8		 4o1zB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 MET A 114
VAL A 117
LEU A 118
ARG A 121
TRP A 388
PHE A 519
ALA A 528
SER A 531
LEU A 532
 None
BOG  A 604 (-3.9A)
None
BOG  A 604 ( 3.7A)
None
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.07A 4o1zB-4ph9A:
58.8		 4o1zB-4ph9A:
64.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 LEU A 353
SER A 354
TYR A 356
LEU A 508
TRP A 388
VAL A 524
 IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
None
None
IBP  A 601 ( 4.0A)
 1.49A 4otyA-4ph9A:
63.6		 4otyA-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 SER A 354
TYR A 356
LEU A 526
ALA A 528
SER A 531
LEU A 532
 None
IBP  A 601 (-4.5A)
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.11A 4otyA-4ph9A:
63.6		 4otyA-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 SER A 354
TYR A 356
LEU A 526
GLY A 527
ALA A 528
LEU A 532
 None
IBP  A 601 (-4.5A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 1.36A 4otyA-4ph9A:
63.6		 4otyA-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
LEU A 385
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.59A 4otyA-4ph9A:
63.6		 4otyA-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.63A 4otyA-4ph9A:
63.6		 4otyA-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.37A 4otyA-4ph9A:
63.6		 4otyA-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 12 SER A 354
TYR A 356
LEU A 526
VAL A 524
ALA A 528
SER A 531
LEU A 532
 None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.27A 4otyB-4ph9A:
63.6		 4otyB-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		7 / 12 SER A 354
TYR A 356
LEU A 526
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 1.37A 4otyB-4ph9A:
63.6		 4otyB-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
LEU A 385
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.56A 4otyB-4ph9A:
63.6		 4otyB-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.58A 4otyB-4ph9A:
63.6		 4otyB-4ph9A:
99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.33A 4otyB-4ph9A:
63.6		 4otyB-4ph9A:
99.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 ASN A 196
GLY A 194
GLN A 193
LEU A 353
THR A 579
 None
None
None
IBP  A 601 ( 4.7A)
None
 1.48A 4p6xG-4ph9A:
undetectable		 4p6xG-4ph9A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 ASN A 196
GLY A 194
GLN A 193
LEU A 353
THR A 579
 None
None
None
IBP  A 601 ( 4.7A)
None
 1.45A 4p6xI-4ph9A:
undetectable		 4p6xI-4ph9A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 LEU A 535
ASN A 538
GLY A 537
GLN A 209
ILE A 338
 EDO  A 616 ( 4.4A)
None
None
None
None
 1.11A 4p6xI-4ph9A:
undetectable		 4p6xI-4ph9A:
19.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
MET A 523
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.56A 4rrwA-4ph9A:
63.7		 4rrwA-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.73A 4rrwA-4ph9A:
63.7		 4rrwA-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
MET A 523
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.55A 4rrwB-4ph9A:
63.8		 4rrwB-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.74A 4rrwB-4ph9A:
63.8		 4rrwB-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
LEU A 385
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.77A 4rrwC-4ph9A:
63.7		 4rrwC-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.72A 4rrwC-4ph9A:
63.7		 4rrwC-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.32A 4rrwC-4ph9A:
63.7		 4rrwC-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 LEU A 353
SER A 354
TYR A 356
LEU A 385
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.65A 4rrwD-4ph9A:
63.8		 4rrwD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.59A 4rrwD-4ph9A:
63.8		 4rrwD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.36A 4rrwD-4ph9A:
63.8		 4rrwD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.22A 4rrwD-4ph9A:
63.8		 4rrwD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 1.30A 4rrwD-4ph9A:
63.8		 4rrwD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 TYR A 349
VAL A 350
LEU A 353
TYR A 356
LEU A 385
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.58A 4rrxA-4ph9A:
63.2		 4rrxA-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 TYR A 349
VAL A 350
LEU A 353
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.72A 4rrxA-4ph9A:
63.2		 4rrxA-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 TYR A 349
VAL A 350
LEU A 353
TYR A 356
LEU A 385
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.62A 4rrxB-4ph9A:
37.1		 4rrxB-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 TYR A 349
VAL A 350
LEU A 353
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.73A 4rrxB-4ph9A:
37.1		 4rrxB-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
MET A 523
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.56A 4rrzA-4ph9A:
63.7		 4rrzA-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.73A 4rrzA-4ph9A:
63.7		 4rrzA-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
MET A 523
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.55A 4rrzB-4ph9A:
63.8		 4rrzB-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.74A 4rrzB-4ph9A:
63.8		 4rrzB-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
LEU A 385
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.77A 4rrzC-4ph9A:
63.7		 4rrzC-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.72A 4rrzC-4ph9A:
63.7		 4rrzC-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.32A 4rrzC-4ph9A:
63.7		 4rrzC-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 LEU A 353
SER A 354
TYR A 356
LEU A 385
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.65A 4rrzD-4ph9A:
63.8		 4rrzD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.59A 4rrzD-4ph9A:
63.8		 4rrzD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.36A 4rrzD-4ph9A:
63.8		 4rrzD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.22A 4rrzD-4ph9A:
63.8		 4rrzD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		8 / 12 VAL A 350
SER A 354
TYR A 356
LEU A 526
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 1.30A 4rrzD-4ph9A:
63.8		 4rrzD-4ph9A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		9 / 9 ARG A 121
VAL A 350
LEU A 353
SER A 354
TYR A 356
LEU A 360
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.22A 4rs0A-4ph9A:
63.0		 4rs0A-4ph9A:
99.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 8 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 5b1aA-4ph9A:
undetectable
5b1aC-4ph9A:
undetectable
5b1aP-4ph9A:
undetectable		 5b1aA-4ph9A:
20.29
5b1aC-4ph9A:
20.75
5b1aP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.22A 5b1aN-4ph9A:
undetectable
5b1aP-4ph9A:
undetectable		 5b1aN-4ph9A:
20.29
5b1aP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 5b1bN-4ph9A:
undetectable
5b1bP-4ph9A:
undetectable		 5b1bN-4ph9A:
20.29
5b1bP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 5b3sN-4ph9A:
undetectable
5b3sP-4ph9A:
undetectable		 5b3sN-4ph9A:
20.29
5b3sP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 THR A 579
THR A 428
PHE A 199
 None
 0.86A 5cxvA-4ph9A:
undetectable		 5cxvA-4ph9A:
21.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 8 LEU A 353
LEU A 385
TYR A 386
TRP A 388
GLY A 527
 IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
 0.69A 5f1aA-4ph9A:
63.4		 5f1aA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 8 VAL A 350
LEU A 385
TYR A 386
TRP A 388
GLY A 527
ALA A 528
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
 0.20A 5f1aA-4ph9A:
63.4		 5f1aA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 8 VAL A 350
TYR A 386
ALA A 528
SER A 531
 IBP  A 601 (-4.3A)
IBP  A 601 (-4.8A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.74A 5f1aA-4ph9A:
63.4		 5f1aA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 7 VAL A 350
LEU A 385
TYR A 386
TRP A 388
GLY A 527
ALA A 528
 IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
 0.17A 5f1aB-4ph9A:
63.4		 5f1aB-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 7 VAL A 350
TYR A 386
TRP A 388
ALA A 528
SER A 531
 IBP  A 601 (-4.3A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
 0.64A 5f1aB-4ph9A:
63.4		 5f1aB-4ph9A:
88.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 ALA A 152
THR A 207
GLN A 209
PHE A 530
SER A 380
 None
HEM  A 602 ( 4.3A)
None
None
None
 1.27A 5hfjG-4ph9A:
undetectable		 5hfjG-4ph9A:
17.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 385
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.36A 5ikqA-4ph9A:
62.7		 5ikqA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.61A 5ikqA-4ph9A:
62.7		 5ikqA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 VAL A 117
SER A 354
MET A 523
 BOG  A 604 (-3.9A)
None
None
 0.26A 5ikqA-4ph9A:
62.7		 5ikqA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 385
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.32A 5ikqB-4ph9A:
62.9		 5ikqB-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.61A 5ikqB-4ph9A:
62.9		 5ikqB-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.61A 5ikrA-4ph9A:
63.0		 5ikrA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.33A 5ikrA-4ph9A:
63.0		 5ikrA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.72A 5ikrA-4ph9A:
63.0		 5ikrA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 350
LEU A 353
SER A 354
TYR A 356
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.50A 5ikrA-4ph9A:
63.0		 5ikrA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 VAL A 117
LEU A 385
MET A 523
 BOG  A 604 (-3.9A)
None
None
 0.13A 5ikrA-4ph9A:
63.0		 5ikrA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.66A 5ikrB-4ph9A:
62.8		 5ikrB-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.44A 5ikrB-4ph9A:
62.8		 5ikrB-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 SER A 354
LEU A 385
MET A 523
 None
 0.15A 5ikrB-4ph9A:
62.8		 5ikrB-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 VAL A 117
ARG A 121
VAL A 350
SER A 354
TYR A 356
LEU A 385
TRP A 388
MET A 523
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.49A 5iktA-4ph9A:
63.1		 5iktA-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		10 / 12 VAL A 117
ARG A 121
VAL A 350
LEU A 385
TRP A 388
MET A 523
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 (-3.9A)
BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.39A 5iktB-4ph9A:
63.1		 5iktB-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 VAL A 117
VAL A 350
LEU A 353
SER A 354
LEU A 385
TRP A 388
MET A 523
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
None
None
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.33A 5iktB-4ph9A:
63.1		 5iktB-4ph9A:
88.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 TYR A 356
TYR A 386
SER A 531
 IBP  A 601 (-4.5A)
IBP  A 601 (-4.8A)
IBP  A 601 ( 3.3A)
 0.83A 5iktB-4ph9A:
63.1		 5iktB-4ph9A:
88.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 5iy5A-4ph9A:
undetectable
5iy5C-4ph9A:
undetectable		 5iy5A-4ph9A:
20.29
5iy5C-4ph9A:
19.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 ARG A 121
VAL A 350
LEU A 353
TYR A 356
LEU A 360
TYR A 386
TRP A 388
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.47A 5jvzA-4ph9A:
64.0		 5jvzA-4ph9A:
99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
LEU A 353
SER A 354
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 ( 4.7A)
None
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.55A 5jvzB-4ph9A:
64.0		 5jvzB-4ph9A:
99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 ARG A 121
VAL A 350
SER A 354
TYR A 356
LEU A 360
TYR A 386
TRP A 388
GLY A 527
ALA A 528
SER A 531
LEU A 532
 BOG  A 604 ( 3.7A)
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.8A)
None
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.23A 5jvzB-4ph9A:
64.0		 5jvzB-4ph9A:
99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 HIS A  90
GLN A 193
VAL A 350
TYR A 356
LEU A 360
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
None
IBP  A 601 (-4.3A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.42A 5jw1A-4ph9A:
62.6		 5jw1A-4ph9A:
99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 6 VAL A 117
LEU A 353
SER A 354
ARG A 514
ILE A 518
PHE A 519
 BOG  A 604 (-3.9A)
IBP  A 601 ( 4.7A)
None
None
None
None
 0.47A 5jw1A-4ph9A:
62.6		 5jw1A-4ph9A:
99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 HIS A  90
ARG A 121
GLN A 193
LEU A 353
TYR A 356
LEU A 360
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
 None
BOG  A 604 ( 3.7A)
None
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
 0.76A 5jw1B-4ph9A:
62.7		 5jw1B-4ph9A:
99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		11 / 12 HIS A  90
GLN A 193
LEU A 353
TYR A 356
LEU A 360
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
LEU A 532
 None
None
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
IBP  A 601 ( 4.7A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 4.9A)
 0.35A 5jw1B-4ph9A:
62.7		 5jw1B-4ph9A:
99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 6 VAL A 117
VAL A 350
SER A 354
ARG A 514
ILE A 518
PHE A 519
 BOG  A 604 (-3.9A)
IBP  A 601 (-4.3A)
None
None
None
None
 0.30A 5jw1B-4ph9A:
62.7		 5jw1B-4ph9A:
99.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 HIS A  90
GLN A 193
VAL A 350
LEU A 353
TYR A 356
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
None
IBP  A 601 (-4.3A)
IBP  A 601 ( 4.7A)
IBP  A 601 (-4.5A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.25A 5kirA-4ph9A:
62.4		 5kirA-4ph9A:
87.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 ARG A 514
ILE A 518
PHE A 519
 None
 0.21A 5kirA-4ph9A:
62.4		 5kirA-4ph9A:
87.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 12 ALA A 436
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 1.43A 5kirB-4ph9A:
63.0		 5kirB-4ph9A:
87.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		12 / 12 HIS A  90
GLN A 193
VAL A 350
SER A 354
TYR A 356
TRP A 388
ALA A 517
VAL A 524
GLY A 527
ALA A 528
SER A 531
LEU A 532
 None
None
IBP  A 601 (-4.3A)
None
IBP  A 601 (-4.5A)
None
None
IBP  A 601 ( 4.0A)
IBP  A 601 (-3.9A)
IBP  A 601 (-3.4A)
IBP  A 601 ( 3.3A)
IBP  A 601 ( 4.9A)
 0.32A 5kirB-4ph9A:
63.0		 5kirB-4ph9A:
87.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 4 LEU A 353
ARG A 514
ILE A 518
PHE A 519
 IBP  A 601 ( 4.7A)
None
None
None
 0.34A 5kirB-4ph9A:
63.0		 5kirB-4ph9A:
87.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_C_Z80C401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 9 ILE A 565
PHE A 202
VAL A 424
ASN A 572
ILE A 305
 None
None
None
EDO  A 612 ( 4.5A)
None
 1.32A 5lg3C-4ph9A:
0.3		 5lg3C-4ph9A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 9 ILE A 565
PHE A 202
VAL A 424
ASN A 572
ILE A 305
 None
None
None
EDO  A 612 ( 4.5A)
None
 1.35A 5lg3D-4ph9A:
0.3		 5lg3D-4ph9A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 9 ILE A 565
PHE A 202
VAL A 424
ASN A 572
ILE A 305
 None
None
None
EDO  A 612 ( 4.5A)
None
 1.31A 5lg3I-4ph9A:
undetectable		 5lg3I-4ph9A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 12 ILE A 316
ASN A 572
ALA A 563
SER A 567
ILE A 559
 None
EDO  A 612 ( 4.5A)
EDO  A 612 ( 4.1A)
EDO  A 612 (-2.4A)
None
 0.99A 5mlmA-4ph9A:
undetectable		 5mlmA-4ph9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 10 PRO A 173
MET A 502
ILE A 499
PHE A 479
GLU A 491
 None
None
None
AKR  A 609 (-4.6A)
None
 1.39A 5tixB-4ph9A:
undetectable		 5tixB-4ph9A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 GLY A 226
ARG A 377
ASP A 230
GLN A 331
 None
 1.35A 5ubbA-4ph9A:
undetectable		 5ubbA-4ph9A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 GLY A 228
ARG A 377
ASP A 230
GLN A 242
 EDO  A 616 ( 4.5A)
None
None
None
 1.43A 5ubbA-4ph9A:
undetectable		 5ubbA-4ph9A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 5 GLY A 228
ARG A 377
ASP A 230
GLN A 331
 EDO  A 616 ( 4.5A)
None
None
None
 1.36A 5ubbA-4ph9A:
undetectable		 5ubbA-4ph9A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 5x19N-4ph9A:
undetectable
5x19P-4ph9A:
undetectable		 5x19N-4ph9A:
20.29
5x19P-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.26A 5x1bN-4ph9A:
undetectable
5x1bP-4ph9A:
undetectable		 5x1bN-4ph9A:
20.29
5x1bP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.29A 5x1fN-4ph9A:
undetectable
5x1fP-4ph9A:
undetectable		 5x1fN-4ph9A:
20.29
5x1fP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		3 / 3 LYS A 469
ASN A 465
SER A 463
 None
 1.04A 5yw0A-4ph9A:
undetectable		 5yw0A-4ph9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 5z85C-4ph9A:
undetectable
5z85N-4ph9A:
undetectable
5z85P-4ph9A:
undetectable		 5z85C-4ph9A:
20.75
5z85N-4ph9A:
20.29
5z85P-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 8 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.23A 5zcoA-4ph9A:
undetectable
5zcoC-4ph9A:
undetectable
5zcoP-4ph9A:
undetectable		 5zcoA-4ph9A:
20.29
5zcoC-4ph9A:
20.75
5zcoP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 5zcqN-4ph9A:
undetectable
5zcqP-4ph9A:
undetectable		 5zcqN-4ph9A:
20.29
5zcqP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 VAL A 229
ASN A 538
PRO A 539
ILE A 540
 None
 1.25A 6h7uA-4ph9A:
undetectable		 6h7uA-4ph9A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.22A 6nknA-4ph9A:
undetectable
6nknC-4ph9A:
undetectable		 6nknA-4ph9A:
20.29
6nknC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.26A 6nmfN-4ph9A:
undetectable
6nmfP-4ph9A:
undetectable		 6nmfN-4ph9A:
20.29
6nmfP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 6 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.26A 6nmpA-4ph9A:
undetectable
6nmpC-4ph9A:
undetectable		 6nmpA-4ph9A:
20.29
6nmpC-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		4 / 7 HIS A 387
ASP A 214
THR A 213
HIS A 389
 HEM  A 602 (-3.7A)
None
HEM  A 602 (-3.4A)
HEM  A 602 (-3.3A)
 1.25A 6nmpN-4ph9A:
undetectable
6nmpP-4ph9A:
undetectable		 6nmpN-4ph9A:
20.29
6nmpP-4ph9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 11 SER A 195
LEU A 391
ALA A 203
PHE A 519
PHE A 199
HIS A 352
 None
None
HEM  A 602 ( 3.9A)
None
None
None
 1.40A 6qgbA-4ph9A:
undetectable		 6qgbA-4ph9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 10 SER A 195
ALA A 203
PHE A 519
PHE A 199
HIS A 352
 None
HEM  A 602 ( 3.9A)
None
None
None
 1.30A 6qgbB-4ph9A:
undetectable		 6qgbB-4ph9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 10 SER A 195
LEU A 391
PHE A 519
PHE A 199
HIS A 352
 None
 1.30A 6qgbB-4ph9A:
undetectable		 6qgbB-4ph9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_C_BEZC701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 9 SER A 195
LEU A 391
PHE A 519
PHE A 199
HIS A 352
 None
 1.31A 6qgbC-4ph9A:
0.8		 6qgbC-4ph9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 10 SER A 195
ALA A 203
PHE A 519
PHE A 199
HIS A 352
 None
HEM  A 602 ( 3.9A)
None
None
None
 1.29A 6qgbD-4ph9A:
undetectable		 6qgbD-4ph9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 10 SER A 195
LEU A 391
PHE A 519
PHE A 199
HIS A 352
 None
 1.28A 6qgbD-4ph9A:
undetectable		 6qgbD-4ph9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 11 SER A 195
ALA A 203
PHE A 519
PHE A 199
HIS A 352
 None
HEM  A 602 ( 3.9A)
None
None
None
 1.30A 6qgbE-4ph9A:
undetectable		 6qgbE-4ph9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		5 / 11 SER A 195
LEU A 391
PHE A 519
PHE A 199
HIS A 352
 None
 1.29A 6qgbE-4ph9A:
undetectable		 6qgbE-4ph9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4ph9 PROSTAGLANDIN G/H
SYNTHASE 2
(Mus
musculus) 		6 / 10 SER A 195
LEU A 391
ALA A 203
PHE A 519
PHE A 199
HIS A 352
 None
None
HEM  A 602 ( 3.9A)
None
None
None
 1.42A 6qgbF-4ph9A:
undetectable		 6qgbF-4ph9A:
19.90