SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pht'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X 140
LEU X  64
VAL X  62
SER X 163
SER X 227
 None
 1.13A 1dfoA-4phtX:
undetectable		 1dfoA-4phtX:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X 140
LEU X  64
VAL X  62
SER X 163
SER X 227
 None
 1.12A 1dfoB-4phtX:
undetectable		 1dfoB-4phtX:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X 140
LEU X  64
VAL X  62
SER X 163
SER X 227
 None
 1.12A 1dfoC-4phtX:
undetectable		 1dfoC-4phtX:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X 140
LEU X  64
VAL X  62
SER X 163
SER X 227
 None
 1.12A 1dfoD-4phtX:
undetectable		 1dfoD-4phtX:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X 140
LEU X  64
VAL X  62
SER X 163
SER X 227
 None
 1.15A 1eqbA-4phtX:
undetectable		 1eqbA-4phtX:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X 140
LEU X  64
VAL X  62
SER X 163
SER X 227
 None
 1.14A 1eqbB-4phtX:
undetectable		 1eqbB-4phtX:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X 140
LEU X  64
VAL X  62
SER X 163
SER X 227
 None
 1.14A 1eqbC-4phtX:
undetectable		 1eqbC-4phtX:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X 140
LEU X  64
VAL X  62
SER X 163
SER X 227
 None
 1.14A 1eqbD-4phtX:
undetectable		 1eqbD-4phtX:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		4 / 6 PHE X 193
ASP X 145
ASP X 146
PRO X 143
 None
 1.05A 1ilqA-4phtX:
undetectable
1ilqC-4phtX:
undetectable		 1ilqA-4phtX:
14.05
1ilqC-4phtX:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 ILE A 149
ILE A 138
LEU A 222
VAL A 203
ILE A 131
 None
 0.77A 1oipA-4phtA:
undetectable		 1oipA-4phtA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		3 / 3 ARG X  51
VAL X   7
TRP X  19
 None
 1.25A 1vagA-4phtX:
undetectable		 1vagA-4phtX:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		3 / 3 VAL X  93
ASP X  94
GLU X  86
 None
 0.70A 2qeuA-4phtX:
undetectable		 2qeuA-4phtX:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		3 / 3 VAL X  93
ASP X  94
GLU X  86
 None
 0.69A 2qeuC-4phtX:
undetectable		 2qeuC-4phtX:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		3 / 3 MET A 351
GLU A 288
ASP A 294
 None
 1.10A 3a25A-4phtA:
undetectable		 3a25A-4phtA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 ASP A 154
ILE A 440
GLY A 478
THR A 438
THR A 487
 None
 1.12A 3eeyC-4phtA:
2.7		 3eeyC-4phtA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 ASP A 154
ILE A 440
GLY A 478
THR A 438
THR A 487
 None
 1.13A 3eeyE-4phtA:
3.6		 3eeyE-4phtA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 ASP A 154
ILE A 440
GLY A 478
THR A 438
THR A 487
 None
 1.11A 3eeyF-4phtA:
4.1		 3eeyF-4phtA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus;
Vibrio
vulnificus) 		3 / 3 ARG X 116
ASP X 123
ASP A 289
 None
 0.80A 3jayA-4phtX:
2.0		 3jayA-4phtX:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		4 / 8 THR A 262
LEU X  41
GLN X 128
ALA X 127
 ANP  A 602 (-4.1A)
None
None
None
 1.04A 3kp6A-4phtA:
undetectable		 3kp6A-4phtA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		4 / 8 HIS A 455
LEU A 257
LEU A 366
SER A 377
 None
 0.97A 3lm8B-4phtA:
2.9
3lm8D-4phtA:
3.1		 3lm8B-4phtA:
18.47
3lm8D-4phtA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		3 / 3 SER A  17
PHE A  22
LYS A  23
 None
 0.89A 3u88A-4phtA:
undetectable		 3u88A-4phtA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 GLY A 382
LEU A 349
GLY A 254
ALA A 359
PHE A 245
 None
 1.04A 3vywC-4phtA:
undetectable		 3vywC-4phtA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 0.98A 4coxA-4phtX:
undetectable		 4coxA-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 0.97A 4coxB-4phtX:
undetectable		 4coxB-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 0.97A 4coxD-4phtX:
undetectable		 4coxD-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus;
Vibrio
vulnificus) 		4 / 4 PRO X  82
LEU X  85
ILE X  89
ARG A  53
 None
 1.33A 4f4dA-4phtX:
undetectable		 4f4dA-4phtX:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 PHE A  98
ALA A 125
VAL A 160
LEU A 161
ILE A 140
 None
 1.11A 4g1bA-4phtA:
2.3		 4g1bA-4phtA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 LEU A 223
ASP A 204
VAL A 205
SER A 195
ALA A 179
 None
 1.33A 4nc3A-4phtA:
undetectable		 4nc3A-4phtA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 1.05A 4otyA-4phtX:
undetectable		 4otyA-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 1.03A 4otyB-4phtX:
undetectable		 4otyB-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 ILE A 255
ALA A 337
THR A 301
SER A 352
LEU A 319
 None
 1.23A 4qztC-4phtA:
undetectable		 4qztC-4phtA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 1.06A 4rrwC-4phtX:
undetectable		 4rrwC-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 1.06A 4rrwD-4phtX:
undetectable		 4rrwD-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 1.06A 4rrzC-4phtX:
undetectable		 4rrzC-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 LEU X  96
VAL X  62
GLY X 112
SER X  99
LEU X 101
 None
 1.06A 4rrzD-4phtX:
undetectable		 4rrzD-4phtX:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus;
Vibrio
vulnificus) 		3 / 3 ARG A  52
GLN A  57
GLU X  12
 None
 0.72A 4tvtA-4phtA:
undetectable		 4tvtA-4phtA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 THR A 353
LEU A 443
ILE A 249
GLY A 273
LEU A 270
 None
 1.17A 5gs4A-4phtA:
undetectable		 5gs4A-4phtA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 12 PHE A  69
LEU A  37
LEU A  26
PHE A  18
ALA A  47
 None
 1.31A 5ieoA-4phtA:
undetectable		 5ieoA-4phtA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		5 / 9 ILE A 255
VAL A 287
LEU A 315
ILE A 318
LEU A 366
 None
 1.48A 5iepA-4phtA:
undetectable		 5iepA-4phtA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		4 / 6 GLU X 156
PRO X  16
GLY X 155
ARG X   8
 None
 1.42A 5jcnB-4phtX:
undetectable		 5jcnB-4phtX:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		4 / 5 HIS X 162
ILE X 149
SER X 168
ALA X 151
 None
 1.18A 5msdA-4phtX:
undetectable		 5msdA-4phtX:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		4 / 8 HIS A 348
VAL A 350
VAL A 326
LEU A 315
 None
 0.76A 5tt3F-4phtA:
undetectable		 5tt3F-4phtA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		5 / 12 ASP X  95
ARG X 116
ILE A 331
ALA A 340
ILE A 318
 None
 1.20A 5vc0A-4phtX:
undetectable		 5vc0A-4phtX:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		4 / 5 HIS X 162
MET X 175
ASN A  44
LEU X 179
 None
 1.38A 5xdhD-4phtX:
undetectable		 5xdhD-4phtX:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_1
(CARNOSINE
N-METHYLTRANSFERASE)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus;
Vibrio
vulnificus) 		4 / 5 GLN A  46
TYR X 178
GLU A  50
ASP X 114
 None
 1.42A 5yf0A-4phtA:
3.4		 5yf0A-4phtA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4pht GENERAL SECRETORY
PATHWAY PROTEIN E
(Vibrio
vulnificus) 		3 / 3 ARG A 150
HIS A 139
ARG A 217
 None
 1.13A 6dwdD-4phtA:
undetectable		 6dwdD-4phtA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4pht TYPE II SECRETION
SYSTEM PROTEIN L
(Vibrio
vulnificus) 		3 / 3 ASP X  61
SER X 168
SER X 139
 None
 0.78A 6mxtA-4phtX:
undetectable		 6mxtA-4phtX:
17.72