SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4phx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SJ4_X_DXCX75_0 (CYTOCHROME C7)	4phx	PROTEIN AGGB (Escherichia coli)	5 / 9	ILE B 3 LEU B 5 ILE B 92 MET B 96 LYS B 65	None	1.47A	3sj4X-4phxB: undetectable	3sj4X-4phxB: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1476_0 (MJ0495-LIKE PROTEIN)	4phx	PROTEIN AGGB (Escherichia coli)	4 / 5	ILE B 26 ALA B 134 HIS B 32 ARG B 29	None	1.01A	4ac9B-4phxB: undetectable 4ac9C-4phxB: undetectable	4ac9B-4phxB: 17.77 4ac9C-4phxB: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1476_0 (TRANSLATION ELONGATION FACTOR SELB)	4phx	PROTEIN AGGB (Escherichia coli)	4 / 5	ILE B 26 ALA B 134 HIS B 32 ARG B 29	None	1.01A	4acaB-4phxB: undetectable 4acaC-4phxB: undetectable	4acaB-4phxB: 17.77 4acaC-4phxB: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCL_A_SAMA301_1 (O-METHYLTRANSFERASE FAMILY PROTEIN)	4phx	PROTEIN AGGB (Escherichia coli)	4 / 5	SER B 74 GLU B 115 LYS B 133 ASN B 40	None	1.24A	4pclA-4phxB: undetectable	4pclA-4phxB: 20.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3SJ4_X_DXCX75_0","CYTOCHROME C7","4phx","PROTEIN AGGB","Escherichia coli",5,"ILE B   3;LEU B   5;ILE B  92;MET B  96;LYS B  65","None","1.47A","3sj4X-4phxB:undetectable","3sj4X-4phxB:20.30"],["4AC9_C_DXCC1476_0","MJ0495-LIKE PROTEIN","4phx","PROTEIN AGGB","Escherichia coli",4,"ILE B  26;ALA B 134;HIS B  32;ARG B  29","None","1.01A","4ac9B-4phxB:undetectable;4ac9C-4phxB:undetectable","4ac9B-4phxB:17.77;4ac9C-4phxB:17.77"],["4ACA_C_DXCC1476_0","TRANSLATION ELONGATION FACTOR SELB","4phx","PROTEIN AGGB","Escherichia coli",4,"ILE B  26;ALA B 134;HIS B  32;ARG B  29","None","1.01A","4acaB-4phxB:undetectable;4acaC-4phxB:undetectable","4acaB-4phxB:17.77;4acaC-4phxB:17.77"],["4PCL_A_SAMA301_1","O-METHYLTRANSFERASE FAMILY PROTEIN","4phx","PROTEIN AGGB","Escherichia coli",4,"SER B  74;GLU B 115;LYS B 133;ASN B  40","None","1.24A","4pclA-4phxB:undetectable","4pclA-4phxB:20.89"]]