SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pj6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 768
LYS A 747
ILE A 713
ILE A 735
THR A 772
 None
 0.97A 1dhiA-4pj6A:
undetectable		 1dhiA-4pj6A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 768
LYS A 747
ILE A 713
ILE A 735
THR A 772
 None
 0.96A 1dhjA-4pj6A:
undetectable		 1dhjA-4pj6A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 5 LYS A 386
LEU A 444
GLU A 385
ALA A 382
 None
 1.13A 1eta1-4pj6A:
undetectable		 1eta1-4pj6A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 5 LYS A 386
LEU A 444
GLU A 385
ALA A 382
 None
 1.13A 1eta2-4pj6A:
undetectable		 1eta2-4pj6A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 6 LYS A 386
LEU A 444
GLU A 385
ALA A 382
 None
 1.13A 1etb1-4pj6A:
undetectable		 1etb1-4pj6A:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.84A 1j36A-4pj6A:
5.4		 1j36A-4pj6A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.85A 1j36B-4pj6A:
5.4		 1j36B-4pj6A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 HIS A 464
GLU A 465
HIS A 468
GLU A 487
PHE A 550
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 1.35A 1j37A-4pj6A:
5.1		 1j37A-4pj6A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.81A 1j37A-4pj6A:
5.1		 1j37A-4pj6A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 HIS A 464
GLU A 465
HIS A 468
GLU A 487
PHE A 550
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 1.35A 1j37B-4pj6A:
5.4		 1j37B-4pj6A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.82A 1j37B-4pj6A:
5.4		 1j37B-4pj6A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 HIS A 464
GLU A 465
HIS A 468
GLU A 487
PHE A 550
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 1.31A 1o86A-4pj6A:
5.5		 1o86A-4pj6A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.89A 1o86A-4pj6A:
5.5		 1o86A-4pj6A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 768
LYS A 747
ILE A 713
ILE A 735
THR A 772
 None
 0.99A 1ra3A-4pj6A:
undetectable		 1ra3A-4pj6A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 768
LYS A 747
ILE A 713
ILE A 735
THR A 772
 None
 1.06A 1re7A-4pj6A:
undetectable		 1re7A-4pj6A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 6 ASP A 454
LEU A 457
VAL A 458
ILE A 461
 None
 0.83A 1s9qA-4pj6A:
undetectable		 1s9qA-4pj6A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 7 ARG A 920
ASN A 891
TYR A 881
ILE A 927
 None
 1.41A 1tdnA-4pj6A:
undetectable		 1tdnA-4pj6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.81A 1v7zA-4pj6A:
undetectable		 1v7zA-4pj6A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.81A 1v7zB-4pj6A:
undetectable		 1v7zB-4pj6A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.82A 1v7zC-4pj6A:
undetectable		 1v7zC-4pj6A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.83A 1v7zD-4pj6A:
undetectable		 1v7zD-4pj6A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.83A 1v7zE-4pj6A:
undetectable		 1v7zE-4pj6A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.83A 1v7zF-4pj6A:
undetectable		 1v7zF-4pj6A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 6 ASP A 281
GLU A 365
TYR A 325
LYS A 287
 None
 1.49A 1yc2A-4pj6A:
undetectable
1yc2B-4pj6A:
undetectable
1yc2E-4pj6A:
undetectable		 1yc2A-4pj6A:
14.72
1yc2B-4pj6A:
14.72
1yc2E-4pj6A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 TYR A 177
PHE A 303
ALA A 299
ILE A 243
ILE A 245
 None
 1.15A 2bjfA-4pj6A:
undetectable		 2bjfA-4pj6A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 10 LEU A1025
PHE A 750
LEU A 787
LEU A 779
ILE A 775
 None
 0.95A 2bxeB-4pj6A:
undetectable		 2bxeB-4pj6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 LEU A1025
PHE A 750
LEU A 787
LEU A 779
ILE A 775
 None
 1.02A 2bxqA-4pj6A:
3.0		 2bxqA-4pj6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.81A 2c6nA-4pj6A:
5.5		 2c6nA-4pj6A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.87A 2c6nB-4pj6A:
5.8		 2c6nB-4pj6A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 6 HIS A 934
TYR A 972
ARG A 929
GLY A 932
 None
 1.29A 2i30A-4pj6A:
undetectable		 2i30A-4pj6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		3 / 3 GLY A 428
ARG A 439
TYR A 275
 None
 0.85A 2opxA-4pj6A:
undetectable		 2opxA-4pj6A:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 6 LYS A 386
LEU A 444
GLU A 385
ALA A 382
 None
 1.11A 2roxB-4pj6A:
undetectable		 2roxB-4pj6A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 HIS A 464
GLU A 465
HIS A 468
GLU A 487
PHE A 550
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 1.33A 2x8zA-4pj6A:
6.4		 2x8zA-4pj6A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.81A 2x8zA-4pj6A:
6.4		 2x8zA-4pj6A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.85A 2x91A-4pj6A:
4.0		 2x91A-4pj6A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.82A 3a6jA-4pj6A:
undetectable		 3a6jA-4pj6A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 7 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.80A 3a6jB-4pj6A:
undetectable		 3a6jB-4pj6A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.81A 3a6jC-4pj6A:
undetectable		 3a6jC-4pj6A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.84A 3a6jE-4pj6A:
undetectable		 3a6jE-4pj6A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 8 GLU A 487
HIS A 464
HIS A 468
GLU A 465
 ZN  A1101 ( 1.9A)
ZN  A1101 ( 3.2A)
ZN  A1101 (-3.2A)
LYS  A1102 (-3.4A)
 0.81A 3a6jF-4pj6A:
undetectable		 3a6jF-4pj6A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 5 HIS A 934
TYR A 972
ARG A 929
GLY A 932
 None
 1.18A 3b9mA-4pj6A:
2.1		 3b9mA-4pj6A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		3 / 3 TYR A 495
GLU A 818
ASP A 810
 None
 0.82A 3bxoA-4pj6A:
undetectable		 3bxoA-4pj6A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		3 / 3 TYR A 495
GLU A 818
ASP A 810
 None
 0.81A 3bxoB-4pj6A:
undetectable		 3bxoB-4pj6A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 PHE A 876
VAL A 866
GLY A 867
GLY A 873
ALA A 896
 None
 1.24A 3dh0A-4pj6A:
undetectable		 3dh0A-4pj6A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 5 PHE A 404
PHE A 408
PHE A 492
PHE A 489
 None
 1.48A 3ko0F-4pj6A:
undetectable
3ko0G-4pj6A:
undetectable		 3ko0F-4pj6A:
8.08
3ko0G-4pj6A:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 0.94A 3ln1A-4pj6A:
undetectable		 3ln1A-4pj6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 0.94A 3ln1B-4pj6A:
undetectable		 3ln1B-4pj6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 0.95A 3ln1C-4pj6A:
2.3		 3ln1C-4pj6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 0.94A 3ln1D-4pj6A:
undetectable		 3ln1D-4pj6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 1.01A 3nt1A-4pj6A:
undetectable		 3nt1A-4pj6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 1.00A 3nt1B-4pj6A:
undetectable		 3nt1B-4pj6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 HIS A 464
GLU A 465
HIS A 468
GLU A 487
PHE A 550
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 1.33A 4c2pA-4pj6A:
5.6		 4c2pA-4pj6A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 HIS A 464
GLU A 465
HIS A 468
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
ZN  A1101 ( 1.9A)
None
 0.84A 4c2pA-4pj6A:
5.6		 4c2pA-4pj6A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 6 ILE A 362
GLY A 364
ILE A 387
ILE A 422
LEU A 435
 None
 1.07A 4o8fB-4pj6A:
undetectable		 4o8fB-4pj6A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 6 LEU A 556
HIS A 468
HIS A 464
GLU A 487
 None
ZN  A1101 (-3.2A)
ZN  A1101 ( 3.2A)
ZN  A1101 ( 1.9A)
 0.89A 4pahA-4pj6A:
undetectable		 4pahA-4pj6A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		6 / 12 HIS A 464
GLU A 465
HIS A 468
TRP A 480
GLU A 487
TYR A 549
 ZN  A1101 ( 3.2A)
LYS  A1102 (-3.4A)
ZN  A1101 (-3.2A)
None
ZN  A1101 ( 1.9A)
None
 0.79A 4r7lA-4pj6A:
42.6		 4r7lA-4pj6A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 7 PHE A 294
ALA A 360
ILE A 319
LEU A 179
 None
 0.86A 4uymA-4pj6A:
undetectable		 4uymA-4pj6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 7 PHE A 294
ALA A 360
ILE A 319
LEU A 179
 None
 0.95A 4uymB-4pj6A:
undetectable		 4uymB-4pj6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		3 / 3 GLU A 759
HIS A 761
ASP A 727
 None
NAG  A1109 (-4.2A)
None
 0.81A 5c0oG-4pj6A:
undetectable		 5c0oG-4pj6A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 10 LEU A 894
GLU A 887
ARG A 920
GLY A 879
LEU A 877
 None
 1.41A 5dxbA-4pj6A:
undetectable		 5dxbA-4pj6A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 768
LYS A 747
ILE A 713
ILE A 735
THR A 772
 None
 0.96A 5e8qA-4pj6A:
undetectable		 5e8qA-4pj6A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 768
LYS A 747
ILE A 713
ILE A 735
THR A 772
 None
 0.93A 5eajA-4pj6A:
undetectable		 5eajA-4pj6A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		3 / 3 ILE A 320
MET A 188
ASP A 322
 None
None
NAG  A1103 (-3.1A)
 0.81A 5h2uA-4pj6A:
undetectable		 5h2uA-4pj6A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A 194
THR A 292
LYS A 318
ILE A 319
SER A 329
 None
 1.28A 5hgcA-4pj6A:
undetectable		 5hgcA-4pj6A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 1.00A 5ikrB-4pj6A:
undetectable		 5ikrB-4pj6A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 1.00A 5jvzA-4pj6A:
undetectable		 5jvzA-4pj6A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 VAL A1006
LEU A 524
VAL A 967
GLY A 969
ALA A 968
 None
 0.93A 5jw1A-4pj6A:
undetectable		 5jw1A-4pj6A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 7 PRO A 304
TYR A 263
ILE A 216
ILE A 245
 None
 0.89A 5murB-4pj6A:
undetectable		 5murB-4pj6A:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 768
LYS A 747
ILE A 713
ILE A 735
THR A 772
 None
 0.96A 5ujxA-4pj6A:
undetectable		 5ujxA-4pj6A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 4 GLU A 825
THR A 829
THR A 772
LEU A 799
 None
 1.45A 5v96A-4pj6A:
undetectable		 5v96A-4pj6A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 4 GLU A 825
THR A 829
THR A 772
LEU A 799
 None
 1.47A 5v96B-4pj6A:
undetectable		 5v96B-4pj6A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 4 GLU A 825
THR A 829
THR A 772
LEU A 799
 None
 1.46A 5v96C-4pj6A:
undetectable		 5v96C-4pj6A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 4 GLU A 825
THR A 829
THR A 772
LEU A 799
 None
 1.45A 5v96D-4pj6A:
undetectable		 5v96D-4pj6A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 GLU A 487
VAL A 420
GLN A 469
PHE A 438
ILE A 422
 ZN  A1101 ( 1.9A)
None
None
None
None
 1.41A 6becA-4pj6A:
3.8
6becB-4pj6A:
undetectable
6becC-4pj6A:
3.5		 6becA-4pj6A:
21.67
6becB-4pj6A:
21.67
6becC-4pj6A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 11 LEU A 251
VAL A 172
THR A 204
ALA A 244
ALA A 232
 None
 1.04A 6h1lB-4pj6A:
undetectable		 6h1lB-4pj6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_1
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 5 ASN A 330
GLN A 293
TYR A 549
MET A 354
 None
LYS  A1102 ( 4.3A)
None
None
 1.06A 6hlpA-4pj6A:
0.0		 6hlpA-4pj6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 7 TRP A 808
THR A 862
ARG A 817
ASP A 858
 None
 1.16A 6mn4E-4pj6A:
undetectable		 6mn4E-4pj6A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		4 / 6 LEU A 556
HIS A 468
HIS A 464
GLU A 487
 None
ZN  A1101 (-3.2A)
ZN  A1101 ( 3.2A)
ZN  A1101 ( 1.9A)
 0.94A 6pahA-4pj6A:
undetectable		 6pahA-4pj6A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens) 		5 / 12 ALA A 768
LYS A 747
ILE A 713
ILE A 735
THR A 772
 None
 1.09A 7dfrA-4pj6A:
undetectable		 7dfrA-4pj6A:
10.26