SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pjs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		5 / 12 PRO A 141
VAL A 108
ILE A 174
TYR A 146
ILE A 115
 None
 1.49A 3q5pA-4pjsA:
undetectable		 3q5pA-4pjsA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		4 / 7 GLU A  97
LEU A  93
LEU A 114
LEU A 118
 None
 0.57A 4wg0B-4pjsA:
undetectable
4wg0C-4pjsA:
undetectable		 4wg0B-4pjsA:
5.06
4wg0C-4pjsA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		4 / 7 GLU A 167
LEU A 163
LEU A 184
LEU A 188
 None
 0.80A 4wg0B-4pjsA:
undetectable
4wg0C-4pjsA:
undetectable		 4wg0B-4pjsA:
5.06
4wg0C-4pjsA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		4 / 7 LEU A 114
LEU A 118
GLU A  97
LEU A  93
 None
 0.58A 4wg0L-4pjsA:
undetectable
4wg0M-4pjsA:
undetectable		 4wg0L-4pjsA:
5.06
4wg0M-4pjsA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		5 / 12 THR A 218
GLY A 222
LEU A 188
LEU A 194
ALA A 197
 None
 1.04A 5l0zA-4pjsA:
undetectable		 5l0zA-4pjsA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		5 / 12 THR A 253
GLY A 257
LEU A 223
LEU A 229
ALA A 232
 None
 1.02A 5l0zA-4pjsA:
undetectable		 5l0zA-4pjsA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		5 / 10 THR A 218
GLY A 222
LEU A 188
LEU A 194
ALA A 197
 None
 1.04A 5l0zB-4pjsA:
undetectable		 5l0zB-4pjsA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		5 / 12 THR A 148
SER A 116
GLY A 119
ALA A 127
SER A 151
 None
 1.27A 5lf3b-4pjsA:
undetectable		 5lf3b-4pjsA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4pjs PENTATRICOPEPTIDE
REPEAT PROTEIN
(unidentified) 		5 / 12 THR A 148
SER A 116
GLY A 119
ALA A 127
SER A 151
 None
 1.26A 5lf3N-4pjsA:
undetectable		 5lf3N-4pjsA:
21.48