SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.79A 1a7yA-4pmhA:
undetectable
1a7yA-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.79A 1a7yB-4pmhA:
undetectable
1a7yB-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.80A 1i3wE-4pmhA:
undetectable
1i3wE-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.79A 1i3wE-4pmhA:
undetectable
1i3wE-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.81A 1i3wF-4pmhA:
undetectable
1i3wF-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.79A 1i3wG-4pmhA:
undetectable
1i3wG-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.86A 1i3wG-4pmhA:
undetectable
1i3wG-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.82A 1i3wH-4pmhA:
undetectable
1i3wH-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 6 TRP A 292
GLY A 231
ASP A 258
TYR A 267
None
1.30A 1kf6M-4pmhA:
undetectable
1kf6N-4pmhA:
undetectable
1kf6M-4pmhA:
19.71
1kf6N-4pmhA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 8 ASP A 250
SER A 249
GLY A 223
GLY A 174
None
0.68A 1me7A-4pmhA:
undetectable
1me7A-4pmhA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.79A 1mnvD-4pmhA:
undetectable
1mnvD-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.79A 1ovfB-4pmhA:
undetectable
1ovfB-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.80A 1qfiA-4pmhA:
undetectable
1qfiA-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.79A 1qfiB-4pmhA:
undetectable
1qfiB-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.76A 1unjF-4pmhA:
undetectable
1unjF-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.75A 1unjF-4pmhA:
undetectable
1unjF-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.78A 1unjL-4pmhA:
undetectable
1unjL-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.82A 1unjL-4pmhA:
undetectable
1unjL-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.83A 1unjR-4pmhA:
undetectable
1unjR-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.81A 1unjR-4pmhA:
undetectable
1unjR-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.84A 1unjW-4pmhA:
undetectable
1unjW-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.81A 1unjX-4pmhA:
undetectable
1unjX-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.80A 1unjX-4pmhA:
undetectable
1unjX-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.81A 1unmE-4pmhA:
undetectable
1unmE-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 143
THR A 111
PRO A 113
None
0.84A 1unmE-4pmhA:
undetectable
1unmE-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 ARG A 194
SER A 214
TYR A 215
None
0.77A 1x70A-4pmhA:
undetectable
1x70A-4pmhA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 8 LEU A 181
LEU A 195
ALA A 234
PHE A 236
None
0.81A 2vcvP-4pmhA:
undetectable
2vcvP-4pmhA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3V_A_TOPA1169_1
(DIHYDROFOLATE
REDUCTASE)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 12 ALA A 193
ILE A 190
LEU A 181
PHE A 152
ILE A  91
None
1.02A 2w3vA-4pmhA:
undetectable
2w3vA-4pmhA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 12 GLY A 197
THR A 201
LEU A 202
GLU A 222
ILE A 166
None
1.09A 2wa2A-4pmhA:
undetectable
2wa2A-4pmhA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 7 GLY A 231
GLY A 230
LEU A 202
PHE A 236
None
0.65A 3o9mA-4pmhA:
undetectable
3o9mA-4pmhA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 LYS A 155
SER A 147
GLN A 182
None
1.20A 3si7A-4pmhA:
undetectable
3si7A-4pmhA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 12 LEU A 312
VAL A 269
HIS A 191
LEU A 202
VAL A 228
None
1.20A 3sp9B-4pmhA:
undetectable
3sp9B-4pmhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 11 ASN A 168
ALA A 178
ASP A 200
GLY A 145
ILE A 144
None
0.98A 3spkA-4pmhA:
undetectable
3spkA-4pmhA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 12 ASN A 168
ALA A 178
ASP A 200
GLY A 145
ILE A 144
None
0.91A 3spkB-4pmhA:
undetectable
3spkB-4pmhA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 5 GLY A 310
PRO A 308
ASN A 309
TYR A 302
None
1.17A 3u8qA-4pmhA:
undetectable
3u8qA-4pmhA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 11 ILE A  91
ILE A  82
ALA A  58
ALA A  57
VAL A  80
None
0.88A 4h1nA-4pmhA:
undetectable
4h1nA-4pmhA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 THR A 111
PRO A 113
THR A 143
None
0.81A 4hivD-4pmhA:
undetectable
4hivD-4pmhA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 7 ASN A 106
ALA A 170
SER A 169
VAL A 151
None
1.09A 4ijiH-4pmhA:
undetectable
4ijiH-4pmhA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 12 ALA A 130
ASN A  60
ALA A  54
ILE A  51
ILE A  69
None
1.03A 4o2bB-4pmhA:
undetectable
4o2bB-4pmhA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 12 ILE A  91
THR A 219
LEU A 164
LEU A 202
LEU A 181
None
1.43A 4qynB-4pmhA:
undetectable
4qynB-4pmhA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 5 ILE A  82
VAL A 159
ILE A 161
VAL A 154
None
0.70A 4xdtA-4pmhA:
undetectable
4xdtA-4pmhA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 5 THR A  22
ALA A  24
THR A  25
TYR A 265
None
1.12A 5ecmA-4pmhA:
undetectable
5ecmA-4pmhA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 6 ILE A 322
VAL A 254
TYR A 242
VAL A 243
None
0.97A 5jwaH-4pmhA:
undetectable
5jwaH-4pmhA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 9 ASN A 168
ALA A 178
ASP A 200
GLY A 145
ILE A 144
None
0.98A 5kr0B-4pmhA:
undetectable
5kr0B-4pmhA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 9 ASN A 168
ALA A 178
ASP A 200
GLY A 145
ILE A 144
None
1.03A 5kr2C-4pmhA:
undetectable
5kr2C-4pmhA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
5 / 12 ALA A 256
GLY A 310
ASP A 226
ILE A 225
ASP A 293
None
1.04A 5wwsB-4pmhA:
undetectable
5wwsB-4pmhA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
3 / 3 VAL A  44
TYR A  48
GLU A  78
None
0.82A 5zmqD-4pmhA:
undetectable
5zmqE-4pmhA:
undetectable
5zmqD-4pmhA:
17.40
5zmqE-4pmhA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
4pmh PECTINESTERASE
(Sitophilus
oryzae)
4 / 5 GLN A 189
VAL A 159
PRO A  33
THR A  85
None
1.36A 6cduA-4pmhA:
undetectable
6cduB-4pmhA:
undetectable
6cduA-4pmhA:
22.10
6cduB-4pmhA:
22.10