SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pmu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 8 ILE A 211
VAL A 169
MET A 214
GLY A 210
 None
 0.81A 1dzmA-4pmuA:
undetectable		 1dzmA-4pmuA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 4 LEU A 195
ILE A 156
ARG A 164
TRP A 168
 None
 1.41A 1ie9A-4pmuA:
undetectable		 1ie9A-4pmuA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		5 / 12 TYR A 196
GLY A 227
ASP A 226
ILE A 225
GLN A 219
 None
 1.14A 1nt2A-4pmuA:
undetectable		 1nt2A-4pmuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		5 / 10 GLY A 227
VAL A 228
GLY A 229
MET A 230
VAL A 256
 None
 1.04A 1pwyE-4pmuA:
undetectable		 1pwyE-4pmuA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 4 ASP A 266
LEU A 295
LEU A 270
LEU A 268
 None
 1.17A 1u18A-4pmuA:
undetectable		 1u18A-4pmuA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		5 / 10 GLY A 227
VAL A 228
GLY A 229
MET A 230
VAL A 256
 None
 1.14A 1v3qE-4pmuA:
undetectable		 1v3qE-4pmuA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 5 LEU A 295
GLY A 274
PRO A 347
VAL A 348
 None
 0.92A 2aojA-4pmuA:
undetectable		 2aojA-4pmuA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		3 / 3 LYS A 272
TYR A 298
PRO A 269
 None
 1.12A 2j9cC-4pmuA:
undetectable		 2j9cC-4pmuA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 5 LEU A 195
ILE A 156
ARG A 164
TRP A 168
 None
 1.41A 2zlcA-4pmuA:
undetectable		 2zlcA-4pmuA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		3 / 3 TRP A 342
VAL A 333
TRP A 334
 None
 0.89A 3zq8C-4pmuA:
undetectable
3zq8D-4pmuA:
undetectable		 3zq8C-4pmuA:
4.46
3zq8D-4pmuA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 6 GLY A 335
TRP A 334
ARG A 330
GLU A 262
 None
 1.50A 4bqfA-4pmuA:
undetectable		 4bqfA-4pmuA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HZ2_A_BEZA302_0
(GLUTATHIONE
S-TRANSFERASE DOMAIN)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 6 SER A 240
ARG A 313
TYR A 238
TRP A 234
 None
 1.24A 4hz2A-4pmuA:
0.0		 4hz2A-4pmuA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 4 ARG A 164
ILE A 156
TYR A 197
ILE A 211
 None
 1.49A 5odhG-4pmuA:
1.6		 5odhG-4pmuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_B_SAMB401_0
(O-METHYLTRANSFERASE)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		5 / 10 ARG A 330
ALA A 329
GLY A 227
ARG A 224
PHE A 183
 None
 1.33A 6clxB-4pmuA:
1.2		 6clxB-4pmuA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_B_SAMB401_0
(O-METHYLTRANSFERASE)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		5 / 10 ARG A 330
ALA A 329
GLY A 227
PHE A 183
ASP A 151
 None
 1.38A 6clxB-4pmuA:
1.2		 6clxB-4pmuA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 4pmu ENDO-1,4-BETA-XYLANA
SE A
(Xanthomonas
citri) 		4 / 8 PHE A  59
PHE A 358
VAL A 372
SER A  24
 None
 1.22A 6huoC-4pmuA:
undetectable
6huoD-4pmuA:
undetectable		 6huoC-4pmuA:
11.66
6huoD-4pmuA:
14.79