SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pmz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 12 LEU A  52
ALA A  78
GLY A  57
GLN A  90
PHE A  45
 None
 1.38A 1brpA-4pmzA:
undetectable		 1brpA-4pmzA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		3 / 3 GLU A 226
TYR A 190
PHE A 225
 None
 0.82A 1eqbB-4pmzA:
undetectable		 1eqbB-4pmzA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		3 / 3 GLU A 226
TYR A 190
PHE A 225
 None
 0.82A 1eqbA-4pmzA:
undetectable		 1eqbA-4pmzA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		3 / 3 GLU A 226
TYR A 190
PHE A 225
 None
 0.83A 1eqbD-4pmzA:
undetectable		 1eqbD-4pmzA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		3 / 3 GLU A 226
TYR A 190
PHE A 225
 None
 0.83A 1eqbC-4pmzA:
undetectable		 1eqbC-4pmzA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 11 SER A  62
VAL A  63
GLY A  61
GLY A  58
TYR A 154
 None
 1.33A 1iolA-4pmzA:
2.1		 1iolA-4pmzA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 10 ALA A 313
LEU A  25
ARG A 318
ILE A 285
LEU A 257
 None
 1.43A 1qkuA-4pmzA:
undetectable		 1qkuA-4pmzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 10 ALA A 313
LEU A  25
ARG A 318
ILE A 285
LEU A 257
 None
 1.43A 1qkuB-4pmzA:
undetectable		 1qkuB-4pmzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 10 ALA A 313
LEU A  25
ARG A 318
ILE A 285
LEU A 257
 None
 1.43A 1qkuC-4pmzA:
undetectable		 1qkuC-4pmzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 11 VAL A 233
VAL A 275
GLU A 222
ARG A 271
LEU A 257
 None
 1.37A 1t6zB-4pmzA:
undetectable		 1t6zB-4pmzA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 7 HIS A 223
ASN A 141
ASP A 142
THR A 253
 None
 0.99A 2f6dA-4pmzA:
undetectable		 2f6dA-4pmzA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 12 LEU A 209
PHE A 173
LEU A 170
ILE A 218
SER A 164
 None
 1.21A 2hrcA-4pmzA:
undetectable		 2hrcA-4pmzA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 12 GLY A 289
TYR A 302
PRO A 292
GLY A 293
LEU A  33
 None
 1.05A 2plwA-4pmzA:
undetectable		 2plwA-4pmzA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 7 ALA A 263
ALA A 267
PRO A 260
ARG A 271
 None
 1.00A 2ql8A-4pmzA:
undetectable
2ql8B-4pmzA:
undetectable		 2ql8A-4pmzA:
18.73
2ql8B-4pmzA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 5 VAL A 233
THR A 199
THR A 228
ARG A 271
 None
 1.26A 3bjwD-4pmzA:
undetectable		 3bjwD-4pmzA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 8 LEU A 317
TYR A 269
PHE A 255
LEU A 287
 None
 0.65A 3i45A-4pmzA:
undetectable		 3i45A-4pmzA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_C_T1CC392_1
(TETX2 PROTEIN)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 11 ASN A 137
GLY A  58
SER A  62
PRO A 101
GLY A 151
 BXP  A 402 (-3.4A)
None
None
None
None
 1.47A 4a6nC-4pmzA:
undetectable		 4a6nC-4pmzA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 6 GLY A 219
ARG A 177
ILE A 187
LEU A 243
 None
 0.97A 4acbC-4pmzA:
2.5		 4acbC-4pmzA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 11 GLY A  57
GLY A  58
ALA A  78
LEU A  75
GLN A  90
 None
 1.08A 4l8fD-4pmzA:
undetectable		 4l8fD-4pmzA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 12 ALA A 217
ILE A 192
SER A 191
TYR A 190
PRO A 139
 None
 1.21A 4rtpA-4pmzA:
undetectable		 4rtpA-4pmzA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 11 LEU A 133
GLU A 134
GLN A  90
PHE A  89
LEU A  52
 None
 1.18A 4wnuA-4pmzA:
undetectable		 4wnuA-4pmzA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 4pmz XYLANASE
(Xanthomonas
citri) 		5 / 12 GLY A  38
GLY A 289
ASP A 256
TRP A 288
GLY A  57
 None
None
None
BXP  A 402 (-4.1A)
None
 1.24A 5hikA-4pmzA:
2.1		 5hikA-4pmzA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 5 LEU A 303
PHE A 290
LEU A 317
PHE A 273
 None
 1.13A 5iy5P-4pmzA:
undetectable
5iy5W-4pmzA:
undetectable		 5iy5P-4pmzA:
21.94
5iy5W-4pmzA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 6 LEU A  52
ILE A 252
THR A 286
MET A 186
 None
 1.25A 5ljeA-4pmzA:
undetectable		 5ljeA-4pmzA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 4pmz XYLANASE
(Xanthomonas
citri) 		3 / 3 ARG A 311
PRO A 260
TYR A 269
 None
 0.95A 5tzoB-4pmzA:
undetectable		 5tzoB-4pmzA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 5 LEU A 303
PHE A 290
LEU A 317
PHE A 273
 None
 1.05A 5x1fC-4pmzA:
undetectable
5x1fJ-4pmzA:
undetectable		 5x1fC-4pmzA:
21.81
5x1fJ-4pmzA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 5 LEU A 303
PHE A 290
LEU A 317
PHE A 273
 None
 1.17A 5xdxC-4pmzA:
undetectable
5xdxJ-4pmzA:
undetectable		 5xdxC-4pmzA:
22.22
5xdxJ-4pmzA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4pmz XYLANASE
(Xanthomonas
citri) 		4 / 5 LEU A 303
PHE A 290
LEU A 317
PHE A 273
 None
 1.20A 5xdxP-4pmzA:
undetectable
5xdxW-4pmzA:
undetectable		 5xdxP-4pmzA:
22.22
5xdxW-4pmzA:
10.88