SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4po4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		5 / 12 LEU A 148
VAL A 162
LEU A 159
LEU A 167
LEU A 165
 None
 1.26A 1mx1C-4po4A:
undetectable		 1mx1C-4po4A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 4 VAL A 151
ALA A 155
LEU A 159
PHE A 132
 None
 1.19A 1q97B-4po4A:
undetectable		 1q97B-4po4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		5 / 12 LEU A  93
LEU A  69
LEU A  45
LEU A  79
LEU A  76
 None
 1.03A 1sqnB-4po4A:
undetectable		 1sqnB-4po4A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		5 / 12 LEU A 117
LEU A  93
LEU A  69
LEU A 103
LEU A 100
 None
 1.00A 1sqnB-4po4A:
undetectable		 1sqnB-4po4A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		5 / 12 LEU A  71
PHE A  60
GLN A  86
PRO A  56
VAL A 107
 None
 1.26A 1u72A-4po4A:
undetectable		 1u72A-4po4A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 7 ILE A 186
TYR A 181
PHE A 156
ASP A 157
 None
 1.11A 2qebA-4po4A:
undetectable		 2qebA-4po4A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 7 ILE A 186
TYR A 181
PHE A 156
ASP A 157
 None
 1.07A 2qebB-4po4A:
undetectable		 2qebB-4po4A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 4 GLU A  92
ARG A  94
ASN A  48
ASP A  72
 None
 1.41A 2zq9A-4po4A:
undetectable		 2zq9A-4po4A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 6 LEU A 119
PHE A 132
ALA A 155
LEU A 148
 None
 0.94A 3t3zA-4po4A:
undetectable		 3t3zA-4po4A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 6 LEU A 119
PHE A 132
ALA A 155
LEU A 148
 None
 0.95A 3t3zB-4po4A:
undetectable		 3t3zB-4po4A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 6 LEU A 119
PHE A 132
ALA A 155
LEU A 148
 None
 0.97A 3t3zD-4po4A:
undetectable		 3t3zD-4po4A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 8 LEU A 182
VAL A 208
LEU A 141
LEU A 165
 None
 0.81A 4l1xA-4po4A:
undetectable		 4l1xA-4po4A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		5 / 12 LEU A  93
LEU A  66
LEU A  71
ALA A  59
ILE A  55
 None
 1.15A 4x1yB-4po4A:
undetectable		 4x1yB-4po4A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		4 / 7 THR A  23
PRO A  21
THR A  17
SER A  14
 None
 1.27A 5b6iA-4po4A:
undetectable		 5b6iA-4po4A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NVP_A_ACAA18_1
(ENVELOPE
GLYCOPROTEIN,GP41)		 4po4 LAMPETRA PLANERI
VLRC
(Lampetra
planeri) 		5 / 12 ASN A  48
GLN A  46
LEU A  69
GLU A  92
LEU A  93
 None
 1.44A 5nvpA-4po4A:
undetectable		 5nvpA-4po4A:
15.03