SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4poi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_A_SORA1343_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	4poi	PUTATIVE PERIPLASMIC PROTEIN (Bacteroides caccae)	4 / 6	ARG A 122 HIS A 44 ARG A 43 ILE A 98	None	0.92A	5a06A-4poiA: undetectable	5a06A-4poiA: 15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MRA_B_DM2B204_1 (SORCIN)	4poi	PUTATIVE PERIPLASMIC PROTEIN (Bacteroides caccae)	4 / 6	TYR A 65 THR A 63 ASP A 78 GLY A 81	None	1.10A	5mraA-4poiA: undetectable 5mraB-4poiA: undetectable	5mraA-4poiA: 21.47 5mraB-4poiA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_A_TLFA300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	4poi	PUTATIVE PERIPLASMIC PROTEIN (Bacteroides caccae)	5 / 12	PHE A 137 PHE A 139 VAL A 99 VAL A 135 HIS A 110	None	1.19A	6ap6A-4poiA: undetectable	6ap6A-4poiA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_B_TLFB300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	4poi	PUTATIVE PERIPLASMIC PROTEIN (Bacteroides caccae)	5 / 12	PHE A 137 PHE A 139 VAL A 99 VAL A 135 HIS A 110	None	1.19A	6ap6B-4poiA: undetectable	6ap6B-4poiA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_C_PCFC607_0 (CYTOCHROME B)	4poi	PUTATIVE PERIPLASMIC PROTEIN (Bacteroides caccae)	5 / 10	ALA A 103 TYR A 106 PHE A 139 PHE A 137 VAL A 129	None	1.36A	6hu9C-4poiA: undetectable	6hu9C-4poiA: 13.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5A06_A_SORA1343_0","ALDOSE-ALDOSE OXIDOREDUCTASE","4poi","PUTATIVE PERIPLASMIC PROTEIN","Bacteroides caccae",4,"ARG A 122;HIS A  44;ARG A  43;ILE A  98","None","0.92A","5a06A-4poiA:undetectable","5a06A-4poiA:15.68"],["5MRA_B_DM2B204_1","SORCIN;SORCIN","4poi","PUTATIVE PERIPLASMIC PROTEIN","Bacteroides caccae",4,"TYR A  65;THR A  63;ASP A  78;GLY A  81","None","1.10A","5mraA-4poiA:undetectable;5mraB-4poiA:undetectable","5mraA-4poiA:21.47;5mraB-4poiA:21.47"],["6AP6_A_TLFA300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","4poi","PUTATIVE PERIPLASMIC PROTEIN","Bacteroides caccae",5,"PHE A 137;PHE A 139;VAL A  99;VAL A 135;HIS A 110","None","1.19A","6ap6A-4poiA:undetectable","6ap6A-4poiA:20.36"],["6AP6_B_TLFB300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","4poi","PUTATIVE PERIPLASMIC PROTEIN","Bacteroides caccae",5,"PHE A 137;PHE A 139;VAL A  99;VAL A 135;HIS A 110","None","1.19A","6ap6B-4poiA:undetectable","6ap6B-4poiA:20.36"],["6HU9_C_PCFC607_0","CYTOCHROME B","4poi","PUTATIVE PERIPLASMIC PROTEIN","Bacteroides caccae",5,"ALA A 103;TYR A 106;PHE A 139;PHE A 137;VAL A 129","None","1.36A","6hu9C-4poiA:undetectable","6hu9C-4poiA:13.70"]]