SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 4pql TRUNCATED
REPLICATION PROTEIN
REPA
(Staphylococcus
aureus) 		5 / 12 LEU A  89
LEU A 108
LEU A 110
ILE A  42
LEU A  82
 None
 1.25A 1g50B-4pqlA:
undetectable		 1g50B-4pqlA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 4pql TRUNCATED
REPLICATION PROTEIN
REPA
(Staphylococcus
aureus) 		5 / 11 LEU A  89
LEU A 108
LEU A 110
ILE A  42
LEU A  82
 None
 1.24A 1g50C-4pqlA:
undetectable		 1g50C-4pqlA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4pql TRUNCATED
REPLICATION PROTEIN
REPA
(Staphylococcus
aureus) 		4 / 7 ALA A  41
TYR A  40
ARG A  44
TYR A  66
 EDO  A 203 (-3.8A)
None
EDO  A 203 (-4.2A)
None
 1.01A 2ajvH-4pqlA:
undetectable
2ajvL-4pqlA:
undetectable		 2ajvH-4pqlA:
15.32
2ajvL-4pqlA:
20.83