SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 4pri TK3 TCR BETA CHAIN
(Homo
sapiens) 		3 / 3 PRO E  25
PHE E 115
LYS E   2
 None
 1.21A 3bjwG-4priE:
undetectable		 3bjwG-4priE:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 4pri TK3 TCR BETA CHAIN
(Homo
sapiens) 		4 / 8 GLN E   6
ALA E  78
GLN E  79
HIS E  86
 None
 1.14A 5km8A-4priE:
undetectable
5km8B-4priE:
undetectable		 5km8A-4priE:
19.59
5km8B-4priE:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 4pri TK3 TCR BETA CHAIN
(Homo
sapiens) 		3 / 3 GLU E  88
ASP E  84
PRO E  83
 None
 0.78A 6berA-4priE:
undetectable		 6berA-4priE:
6.61