SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ps0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 4ps0 CASPASE-3
(Homo
sapiens) 		4 / 7 LEU A 219
PRO A 155
VAL A 115
MET A  44
 None
 1.27A 2hrcA-4ps0A:
2.0		 2hrcA-4ps0A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 4ps0 CASPASE-3
(Homo
sapiens) 		4 / 4 GLU A 123
GLY A 165
THR A 166
GLU A 167
 None
 0.65A 3e9xA-4ps0A:
0.9		 3e9xA-4ps0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 4ps0 CASPASE-3
(Homo
sapiens) 		4 / 7 PRO A 201
GLU A 124
SER A 198
THR A  67
 None
 1.22A 4uacA-4ps0A:
undetectable		 4uacA-4ps0A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 4ps0 CASPASE-3
(Homo
sapiens) 		3 / 3 LYS A 110
ARG A 111
HIS A 108
 None
 0.84A 4zbrA-4ps0A:
undetectable		 4zbrA-4ps0A:
18.43