SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ps6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 4ps6 INHIBITOR OF
VERTEBRATE LYSOZYME
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 131
PHE A  47
MET A  46
LEU A  93
 None
 1.12A 1ea1A-4ps6A:
undetectable		 1ea1A-4ps6A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 4ps6 INHIBITOR OF
VERTEBRATE LYSOZYME
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 142
GLY A 106
VAL A  95
VAL A  53
LEU A  93
 None
 1.44A 1mx1E-4ps6A:
undetectable		 1mx1E-4ps6A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 4ps6 INHIBITOR OF
VERTEBRATE LYSOZYME
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  97
ALA A  80
PHE A  47
ALA A  60
 None
 0.88A 3t3sF-4ps6A:
undetectable		 3t3sF-4ps6A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 4ps6 INHIBITOR OF
VERTEBRATE LYSOZYME
(Pseudomonas
aeruginosa) 		3 / 3 LYS A  55
TRP A  56
SER A  58
 None
 1.24A 5nwwA-4ps6A:
undetectable		 5nwwA-4ps6A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4ps6 INHIBITOR OF
VERTEBRATE LYSOZYME
(Pseudomonas
aeruginosa) 		4 / 8 VAL A  53
GLY A 106
GLN A 108
LEU A  93
 None
 0.93A 5sxqB-4ps6A:
undetectable		 5sxqB-4ps6A:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 4ps6 INHIBITOR OF
VERTEBRATE LYSOZYME
(Pseudomonas
aeruginosa) 		4 / 8 VAL A  53
GLY A 106
GLN A 108
LEU A  93
 None
 0.93A 5syjA-4ps6A:
undetectable		 5syjA-4ps6A:
12.48